Incidence of carcinoma of the oesophagus and gastric cardia. Changes over time and geographical differences.

Abstract

The results show an increasing incidence of adenocarcinoma in both oesophagus and gastric cardia. Squamous cell carcinomas show a more stable development with a slight decrease of incidence. Adenocarcinoma is now the most common histological type of cancer in the oesophageal/cardia region in Sweden. Results also suggest a possible drift in location of adenocarcinoma from gastric cardia towards oesophagus. Overall a higher incidence was found in the male population and no trends in patient age at onset could be found. Squamous cell carcinoma is still slightly more common in urban regions.

Decreasing morbidity and mortality in 100 consecutive minimally invasive esophagectomies

“…Furthermore, even when performed by expert surgeons at high-volume centers, esophagectomy is associated with high rates of postoperative morbidity, including anastomotic leaks, pneumonia, and tachyarrhythmias [4]. Although operative mortality has progressively declined with the decreasing rate of complications related to the surgery, esophageal cancer continues to have a poor prognosis with an overall 5-year survival rate of approximately 13% [25][26][27][28][29][30].…”

Cancer patients without a known primary: Incidence and survival trends in Sweden 1960–2007

“…Another possibility is that the proportion of adenocarcinomas has increased among tumour types giving rise to CUP cases. Such as shift Á the cause of which remains unknown Á has been reported among patients with oesophageal and gastric cardia cancer [10] as well as among lung cancer cases [11]. One may speculate that it might be related to shifts in population exposure to etiologic factors.…”

Association of C-Reactive Protein Levels and Long-Term Survival after Neoadjuvant Therapy and Esophagectomy for Esophageal Cancer

“…Despite advances in staging, patient selection, and more aggressive treatment, 5-year survival rates are still poor at approximately 30-35%. 1,2 Patients receiving CRT followed by surgery have been shown to have a survival advantage compared to patients undergoing surgery alone. 3 Neoadjuvant CRT downstages tumors and allows higher rates of complete resection.…”