Incidence of biopsy-proven glomerulonephritis

Wirta, Ole; Mustonen, Jukka; Helin, H; Pasternack, Amos

doi:10.1093/ndt/gfm564

Cited by 51 publications

(63 citation statements)

References 20 publications

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“…Since 128,057,352 people resided in Japan in 2010, the estimated rate of renal biopsy was 140.6 to 164.0 per million population. This rate was higher than that in Romania [24], Spain [25], the Czech Republic [10], Denmark [26], and Scotland [27], was similar to that in France [28], and was lower than that in USA, Finland [29], and Australia [30].…”

Section: Discussion and Commentsmentioning

confidence: 61%

Japan Renal Biopsy Registry and Japan Kidney Disease Registry: Committee Report for 2009 and 2010

et al. 2013

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123Clin Exp Nephrol (2013) 17:155-173 DOI 10.1007 nephritic syndrome (55.4 % and 50.0 % in 2009 and 2010, respectively), followed by nephrotic syndrome (22.4 % and 27.0 %); the most frequent pathological diagnosis as classified by the pathogenesis was IgA nephropathy (31.6 % and 30.4 %), followed by primary glomerular diseases (except IgA nephropathy) (27.2 % and 28.1 %). Among the primary glomerular diseases (except IgA nephropathy) in the patients with nephrotic syndrome, membranous nephropathy was the most common histopathology in 2009 (40.3 %) and minor glomerular abnormalities (50.0 %) were the most common in 2010 in native kidneys in the J-RBR. Five new secondary and longitudinal research studies by the J-KDR were started in 2009 and one was started in 2010.

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Section: Discussion and Commentsmentioning

confidence: 61%

Japan Renal Biopsy Registry and Japan Kidney Disease Registry: Committee Report for 2009 and 2010

et al. 2013

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“…In addition, data from local or limited national registries of renal biopsy have been reported from South Korea [10,11], Bahrain [12,13], Brazil [14], Romania [15], China [16], Finland [17], Serbia [18], Pakistan [19] and Belgium [20]. Finally, there are also reports that include epidemiological data only on glomerular diseases from Australia [21], Macedonia [22], France [23], USA [24], Iran [25], Germany [26], Lebanon [27], Peru [28] and Poland [29].…”

Section: Introductionmentioning

confidence: 99%

Epidemiologic data of adult native biopsy-proven renal diseases in Croatia

et al. 2013

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PURPOSE: There is a paucity of epidemiological data on biopsy-proven renal disease in Croatia. The purpose of this report is a review of clinical and histological data, over a period of 15 years, from the single biggest adult native renal biopsy centre in Croatia.METHODS: This report includes data from 922 adult native renal biopsies in patients referred from the whole country and performed in our centre from 1996 till February 2012. Data on age, gender, serum creatinine, urine sediment, 24-hour proteinuria, clinical syndrome and histological diagnosis were collected and analyzed retrospectively. In all patients light, immunofluorescence and electron microscopic analysis was performed.RESULTS: The median age of the patients was 48 years (interquartile range 36-59 years), and the majority of patients were men (57.8%). The most common indication for renal biopsy was nephrotic syndrome (40.3%) followed by asymptomatic urinary abnormalities (31.7%). The most common biopsy-proven renal disease in total was IgA glomerulonephritis (19.3%), followed by FSGS (15.8%) and membranous glomerulonephritis (9.2%). In men similar results were found, while in women the most common were hereditary nephritis (13.4%), FSGS (12.9%) and connective tissue disease-related glomerular disorders (11.6%).CONCLUSION: The presented data are an important contribution to the better understanding of the epidemiology of biopsy-proven renal disease in Croatia and Europe throughout comparison with other registry data. This data should be the basis for the formation of Croatian Registry of Renal Biopsies.

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“…Membranous nephropathy (MGN) is the most common cause of nephrotic syndrome in adults and it remains an important cause of renal failure (1)(2)(3). The design and conduct of therapeutic studies for treatment of MGN remains a challenge because of its relatively slow evolution and highly variable natural history.…”

Section: Introductionmentioning

confidence: 99%

Have We Changed the Outcome in Membranous Nephropathy? A Propensity Study on the Role of Immunosuppressive Therapy

Cattran

Reich

Kim

et al. 2011

Clinical Journal of the American Society of Nephrology

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SummaryBackground and objectives The long-term effect of immunosuppressive therapy (IS) on kidney survival in idiopathic membranous nephropathy (MGN) is debated. The introduction of renin angiotensin blockade, rigorous BP control, and the increasing age at presentation of patients with MGN adds further uncertainty. Given these important changes, we sought to determine whether implementation of IS has altered outcome. Design, setting, participants, & methodsWe prospectively evaluated 280 incident MGN patients from three distinct 10-year periods starting from 1975. ResultsWe found expected changes in treatment regimens but also variations in age, renal function, severity of proteinuria, and BP at presentation over this time. Outcomes did not differ over time if these significant variations in clinical characteristics were not accounted for across the eras. The effect of IS in the 57 patients treated with currently recommended regimens was assessed using propensity adjustment to address selection bias and the effect of newer, conservative therapies. A propensity score estimating the probability of receiving IS permitted the pairing of 39 treated patients with controls with similar high risk of progression of clinical features. Using this approach, IS was associated not only with remissions in proteinuria but also with substantially improved renal survival. ConclusionsThe study confirms that patient presenting characteristics and management regimens have changed significantly over time and the natural history of MGN has been altered. A study of propensitymatched patients confirms that current recommendations for IS have improved outcomes in MGN patients at high risk of progression.

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Incidence of biopsy-proven glomerulonephritis

Abstract: Background. The reported biopsy-proven glomerulonephritis incidence varies according to population characteristics, the unknown true glomerulonephritis incidence and biopsy rate. Reported glomerulonephritis incidence should be evaluated against the biopsy rate.

Cited by 51 publications

References 20 publications

Japan Renal Biopsy Registry and Japan Kidney Disease Registry: Committee Report for 2009 and 2010

Japan Renal Biopsy Registry and Japan Kidney Disease Registry: Committee Report for 2009 and 2010

Epidemiologic data of adult native biopsy-proven renal diseases in Croatia

Have We Changed the Outcome in Membranous Nephropathy? A Propensity Study on the Role of Immunosuppressive Therapy

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