Incidence of atopic disease in a tropical environment: Partial independence from intestinal helminthiasis

The etiological factor for eosinophilia and hyperglobulinemia E in Brazilian school children.

“…It has been reported that the incidence of allergic diseases in tropical area is identical to those in temperate area, especially in urban district (Lynch et al ., 1984) . Anti-house dust IgE antibody was chosen as a marker of allergic diseases in this study , since house dust antigen is the most popular allergen in tropical residents (Lynch et al ., 1984) .…”

“…Anti-house dust IgE antibody was chosen as a marker of allergic diseases in this study , since house dust antigen is the most popular allergen in tropical residents (Lynch et al ., 1984) . The prevalence rates of anti-house dust IgE antibodies were almost the same in children of both VAR and MAD , suggesting that allergic diseases were not involved in the major etiologies for eosinophilia and hyperIgE in VAR children.…”

“…Allergic diseases are another etiological factor for eosinophilia and hyperIgE especially in residents in temperate areas. It has been demonstrated that the morbidity of allergic diseases was not so low even in tropical residents (Lynch et al, 1984) . Therefore the participation of allergic diseases on eosinophilia and hyperIgE in tropical residents also…”

The effect of Enterobius vermicularis infection (oxyuriasis) on eosinophil and IgE levels in allergic rhinitis

“…Lynch et al [5] reported that a history of a strong IgE response in atopic children led to an increased protective response against helminths. The infection intensity was significantly lower compared to nonatopic subjects in that study.…”

Derived Products of Helminth in the Treatment of Inflammation, Allergic Reactions and Anaphylaxis

“…Individuals exposed to helminthes for a short time often have allergic-like manifestations (Cooper, 2009). Lynch and collaborators (Lynch et al, 1984(Lynch et al, , 1987(Lynch et al, , 1992(Lynch et al, , 1997 have shown that the intensity of helminth transmission determines the effect of helminth infection on allergic reactivity -in high income urban areas where the transmission is low, the allergic reactivity is high whereas in urban and rural areas where people are chronically infected by helminthes, the allergic reactivity is low. Geohelminth parasite with pulmonary larval stages, such as Ascaris lumbricoides, Necator americanus, Ancylostoma duodenale and Strongyloides stercoralis, are found to cause Loeffler's syndrome which is characterized by eosinophilic infiltrate into the lungs after parasitic infection (Loefller, 1959).…”