The etiological factor for eosinophilia and hyperglobulinemia E in Brazilian school children.

Abstract

Abstract:The etiology of peripheral blood eosinophilia and hyperglobulinemia E, which are commonly found among residents in tropical area, were studied with two groups were mainly caused by soil-transmitted helminthiases. INTRODUCTIONPeripheral blood eosinophilia and hyperglobulinemia E (hyperIgE) are common laboratory findings among residents in tropical areas (Johansson et al., 1968;Mahmoud, 1984) . It has been empirically supposed that these abnormal findings are caused by helminth infections, which are major health problem in tropical areas. However, the comparisons in the number of eosinophils and serum IgE level between helminth infected and uninfected subjects in one community usually failed to show prominent differences (Bruce-Tagoe et al., 1977;Kaplan et al., 1980). Allergic diseases are another etiological factor for eosinophilia and hyperIgE especially in residents in temperate areas. It has been demonstrated that the morbidity of allergic diseases was not so low even in tropical residents (Lynch et al., 1984) . Therefore the participation of allergic diseases on eosinophilia and hyperIgE in tropical residents also