Incidence, mortality and risk factors of cervical cancer in the world

Momenimovahed, Zohre; Salehiniya, Hamid

doi:10.15419/bmrat.v4i12.386

Cited by 86 publications

(86 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Genetic factors play an essential role in the incidence of cervical cancer [ 35 ]. An important etiological factor for cancerous cervical lesions is a highly prevalent, sexually transmitted infection, HPV.…”

Section: Epidemiology Of Cervical Cancermentioning

confidence: 99%

“…HPV detection and vaccination measures need to be implemented as a means of cervical cancer prevention. Whilst 90% of HPV-induced lesions disappear within 6–12 months, others progress into cancer [ 35 ], with HPV types 16, 18, 45, 33, 35, 52, 51 and 31 associated with cervical cancer [ 45 ].…”

Section: Epidemiology Of Cervical Cancermentioning

confidence: 99%

“…HPVs 16 and 18 induce carcinogenesis by oncoprotein E6 and E7 activities, which inhibit the function of p53 and retinoblastoma tumour suppressor genes [ 5 ]. These oncoproteins are associated with changes in the methylation of both the host and viral DNA by altering cellular pathways that regulate cell adhesion, genetic integrity, cellular control, immune response and, most importantly, apoptosis [ 35 , 47 ].…”

Section: Epidemiology Of Cervical Cancermentioning

confidence: 99%

“…Hence, the introduction of additional synthetic hormones will accelerate cell growth and increase the risk of cancer [ 59 ]. It has been reported that the incidence of cervical cancer doubled in individuals who had consumed steroid hormones for longer than 5 years, with an increase in invasive cervical cancer prevalence in individuals taking injectable progesterone [ 35 , 57 ]. The additional hormones increase the incidence of cervical cancer by increasing the susceptibility of high-risk HPV infections [ 59 ].…”

Section: Epidemiology Of Cervical Cancermentioning

confidence: 99%

See 3 more Smart Citations

Cervical cancer: a meta-analysis, therapy and future of nanomedicine

Venkatas

Singh

2020

ecancer

View full text Add to dashboard Cite

Cervical cancer is one of the leading causes of female death, with an annual mortality rate exceeding 200,000 in developing communities. Despite the past decade bearing witness to a reduction in cervical cancer cases throughout developed countries, the prevalence in developing countries continues to rapidly rise. The increase in cervical cancer cases is attributed to the lack of financial resources and the unavoidable risk factors of the disease. Traditional means of anticancer therapy are compromised by reduced drug potency, non-specificity, negative side effects and the development of multiple drug resistance (MDR), which leads to a decrease in the long-term anticancer therapeutic efficacy. Recent advances in nanomedicine have elucidated the potential of nanoparticles to reduce the side effects and improve the survival rate of patients, by enhancing selective delivery and uptake of photosensitive, therapeutic and genetic material to cervical cancer cells, thereby enhancing antitumour efficiency. This review paper analyses the risk factors and epidemiology of cervical cancer globally, especially in developing communities, whilst demonstrating the enhanced anticancer treatment using selected nanoparticles.

show abstract

Section: Epidemiology Of Cervical Cancermentioning

confidence: 99%

Section: Epidemiology Of Cervical Cancermentioning

confidence: 99%

Section: Epidemiology Of Cervical Cancermentioning

confidence: 99%

Section: Epidemiology Of Cervical Cancermentioning

confidence: 99%

See 2 more Smart Citations

Cervical cancer: a meta-analysis, therapy and future of nanomedicine

Venkatas

Singh

2020

ecancer

View full text Add to dashboard Cite

show abstract

“…Cancer is one of the main causes of mortality worldwide [ 1 , 2 ]. In 2008, 8 million deaths were recorded as a result of malignant diseases, and this figure is estimated to reach 11 million by 2030 [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Investigation of the Association between Drinking Water Habits and the Occurrence of Women Breast Cancer

Keren

Magnezi

Carmon

et al. 2020

IJERPH

View full text Add to dashboard Cite

Risk and protective factors for breast cancer (BC) include lifestyle, diet, reproduction, and others. Increased risk for colon cancer was linked with low water intake. The link between water consumption and BC was scarcely studied. We investigated the association between water and fluid consumption and the occurrence of BC in a retrospective case–control study in the Shaare Zedek Medical Center, Jerusalem, in 206 women aged 25–65 years (106 with newly diagnosed BC, and 100 controls). A food frequency questionnaire (FFQ), consumption of water, foods, and beverages, lifestyle, and other risk and protective factors were recorded. The age of women in both groups was comparable ((M ± SD) 52.7 ± 9.8 and 50.6 ± 11.4 years, respectively (p = 0.29)). Women with BC consumed 20.2% less water (M ± SD=5.28 ± 4.2 and 6.62 ± 4.5 cups/day, respectively, p = 0.02) and 14% less total fluids than controls (M ± SD=2095 ± 937 mL/day and 2431 ± 1087 mL/day, respectively, p = 0.018). Multiple stepwise logistic regression showed that the differences remained significant both for daily water consumption (p = 0.031, CI = 0.462–0.964) and for total daily liquid intake (p = 0.029, CI = 0.938–0.997). Low water and liquids intake as a risk factor for BC may be related to the younger age of our subjects. The effect of age on the potential role of water intake in decreasing BC risk should be investigated.

show abstract

Characterizing online crowdfunding campaigns for patients with kidney cancer

et al. 2021

View full text Add to dashboard Cite

Background Cancer patients incur high care costs; however, there is a paucity of literature characterizing unmet financial obligations for patients with urologic cancers. Kidney cancer patients are particularly burdened by costs associated with novel systemic treatments. This study aimed to ascertain the characteristics of GoFundMe® crowdfunding campaigns for patients with kidney cancer, in order to better understand the financial needs of this population. Methods We performed a cross‐sectional, quantitative, and qualitative analysis of all kidney cancer GoFundMe® campaigns since 2010. Fundraising metrics such as goal funds and amount raised, were extracted. Eight independent investigators collected patient, disease and campaign‐level variables from campaign stories (κ = 0.72). In addition, we performed a content analysis of campaign narratives spotlighting the primary appeal of the patient's life story. Results A total of 486 GoFundMe® kidney cancer campaigns were reviewed. The median goal funds were 10,000USD [IQR = 5000, 20,000] and the median amount raised was 1450USD [IQR = 578, 4050]. Most campaigns were for adult males (53%) and 62% of adults had children. A minority were for pediatric patients (17%). Thirty‐seven percent of adult patients were primary wage earners and 43% reported losing their job or substantially reducing hours due to illness. Twenty‐nine percent reported no insurance or insufficient coverage. Campaigns most frequently sought funds for medical bills (60%), nonmedical bills (27%), and medical travel (23%). Qualitative campaign narratives mostly emphasized patients’ hardship (46.3%) or high moral character (35.2%). Only 8% of campaigns achieved their target funds. Conclusions Despite fundraising efforts, patients with kidney cancer face persistent financial barriers, incurring both medical and nonmedical cost burdens. This may be compounded by limited or no insurance. Cancer care providers should be aware of financial constraints placed on kidney cancer patients, and consider how these may impact treatment regimens.

show abstract

Incidence, mortality and risk factors of cervical cancer in the world

Cited by 86 publications

References 61 publications

Cervical cancer: a meta-analysis, therapy and future of nanomedicine

Cervical cancer: a meta-analysis, therapy and future of nanomedicine

Investigation of the Association between Drinking Water Habits and the Occurrence of Women Breast Cancer

Characterizing online crowdfunding campaigns for patients with kidney cancer

Contact Info

Product

Resources

About