Incidence and significance of gastroesophageal reflux following repair of esophageal atresia and tracheoesophageal fistula and the need for anti-reflux procedures

Parker, A; Christie, Dennis L.; Cahill, John L.

doi:10.1016/s0022-3468(79)80568-0

Cited by 96 publications

(5 citation statements)

References 9 publications

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“…It was later noted that this disorder could be reversed by feeding extracts of alfalfa (3). The active principle was later identified as vitamin K) or phylloquinone, reflecting its origin from plants (4).…”

Section: Questions About Quinones In Infant Nutritionmentioning

confidence: 99%

Reflux and Related Phenomena

Byrne

1989

J. pediatr. gastroenterol. nutr.

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Section: Questions About Quinones In Infant Nutritionmentioning

confidence: 99%

Reflux and Related Phenomena

Byrne

1989

J. pediatr. gastroenterol. nutr.

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“…The prognosis of EA has dramatically improved with recent advances in medical care, but the rate of postoperative complications is still high. One of the most frequent complications after repair of EA is gastroesophageal reflux disease (GERD), which occurs in about 40%–65% of patients 1–3 . GERD may cause regurgitation or vomiting, failure to thrive, apneic spells, barking cough, recurrent pneumonia, chronic respiratory tract disease, and recurrent anastomotic stricture.…”

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confidence: 99%

Predictive factors for fundoplication following esophageal atresia repair

Kambe

Fumino

Sakai

et al. 2022

Pediatrics International

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Background One of the most frequent complications after repair of esophageal atresia (EA) is gastroesophageal reflux disease (GERD). Although GERD‐associated EA is known to often require anti‐reflux surgery, the predicting factors remain unclear. We retrospectively analyzed EA in our institution. Methods Of 65 children with EA treated in our hospital from 1995 to 2018, 45 with Gross C type EA, followed for over 1 year, were enrolled in this study. The patients were divided into fundoplication and non‐fundoplication groups and compared in terms of their clinical features. Results The fundoplication and non‐fundoplication groups included 13 and 32 cases, respectively. On univariate analysis, gestational age, body weight, prenatal diagnosis, polyhydramnios, re‐do surgery, and gap length of the esophagus differed significantly between the groups (P < 0.05). Conclusion Early delivery, low body weight, and a long gap length are, are considered to be risk factors for fundoplication. However, the present study further showed that prenatal diagnosis and polyhydramnios were also significant contributing factors. The presence of a prenatal diagnosis and polyhydramnios may induce preterm delivery, therefore, cases of polyhydramnios due to suspected EA should be managed to prevent early delivery. Better understanding of the postnatal course after surgery is required, especially for prenatal diagnosis cases.

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“…Gastroesophageal reflux (GER) is a common event following EA repair in about 40-65% of patients (1)(2)(3). The cause of GER seems to be secondary to the EA repair itself; however most people believe that an associated factor may be linked to a primary congenital deficiency in the motor function of the esophagus (2)(3)(4). Although the majority of these patients can be successfully treated with a trial of pharmacological treatment, about 28% are refractory to medication and require surgical correction (1,(5)(6)(7).…”

mentioning

confidence: 99%

“…Gastroesophageal reflux (GER) is a common event following EA repair in about 40‐65% of patients (1‐3). The cause of GER seems to be secondary to the EA repair itself; however most people believe that an associated factor may be linked to a primary congenital deficiency in the motor function of the esophagus (2‐4).…”

mentioning

confidence: 99%

“…Conclusions: In our experience laparoscopic antireflux surgery is an appropriate treatment of GER in children operated for EA at birth, independently of the antireflux mechanism adopted; the 31.2% rate of short-term dysphagia presenting as residual respiratory symptoms may be due to a primary dysmotility of the esophagus consequent to the esophageal atresia. Gastroesophageal reflux (GER) is a common event following EA repair in about 40-65% of patients (1)(2)(3). The cause of GER seems to be secondary to the EA repair itself; however most people believe that an associated factor may be linked to a primary congenital deficiency in the motor function of the esophagus (2)(3)(4).…”

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confidence: 99%

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