Incidence and risk factors of atrial fibrillation and atrial arrhythmias in people living with HIV: a systematic review and meta-analysis

Park, Dae Yong; An, Seokyung; Romero, Maria Emilia; Kaur, Amandeep; Ravi, Venkatesh; Huang, Henry; Vij, Aviral

doi:10.1007/s10840-022-01233-w

Cited by 6 publications

(6 citation statements)

References 31 publications

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“…This is further supported by another study that showed that a lower CD4 counts and higher viral loads were associated with an increased incidence of AF [69]. It has been proposed that chronic inflammation may be the trigger for AF in HIV [68].…”

Section: Human Immunodeficiency Virussupporting

confidence: 52%

“…In one study examining over 2 million HIV hospitalizations, AF was the most common arrhythmia (2110 per 100,000) [67]. A meta-analysis consisting of 94,928 pts also demonstrated an increased risk of atrial arrhythmia, including AF, in HIV [68]. This is further supported by another study that showed that a lower CD4 counts and higher viral loads were associated with an increased incidence of AF [69].…”

Section: Human Immunodeficiency Virusmentioning

confidence: 91%

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Cardiac arrhythmias in viral infections

Lee

Garan

Wan

et al. 2023

J Interv Card Electrophysiol

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Background The currentCOVID-19 pandemic has led to many studies examining its arrhythmogenic effects. However, there are many other viruses that are capable of inducing arrhythmias that have not received as much attention. The objective of this study was to review common viruses and identify studies highlighting their arrhythmogenic effects. Methods and resultsIn this review, we examined 15 viruses and the literature regarding their arrhythmogenic effects. The common mechanisms of action appear to be direct invasion of myocytes leading to immune mediated damage, infection of vascular endothelium, and alteration of cardiac ion channels. Conclusions This review highlights the growing evidence that supports the involvement of other viral infections in the development of arrhythmia. Physicians should be aware of these potentially life-threatening effects when caring for patients with these viruses, some of which are very common. Additional studies are required to better understand the complex mechanism and risk factors of cardiac arrhythmias in patients suffered from viral infections to determine whether the processes can be reversed or even prevented.

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Section: Human Immunodeficiency Virussupporting

confidence: 52%

Section: Human Immunodeficiency Virusmentioning

confidence: 91%

Cardiac arrhythmias in viral infections

Lee

Garan

Wan

et al. 2023

J Interv Card Electrophysiol

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“…From references of the retrieved articles and through conducting a hand search using Epistemonikos, we identified an additional 7 eligible studies. 47 , 48 , 49 , 50 , 51 , 52 , 53 Therefore, a total of 70 studies were included.…”

Section: Resultsmentioning

confidence: 99%

The Role of Social Determinants of Health in Cardiovascular Diseases: An Umbrella Review

Teshale

Htun

Owen

et al. 2023

JAHA

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Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Addressing social determinants of health (SDoH) may be the next forefront of reducing the enormous burden of CVD. SDoH can be defined as any social, economic, or environmental factor that influences a health outcome. Comprehensive evidence of the role of SDoH in CVD is lacking, nevertheless. This umbrella review aims to give a comprehensive overview of the role of SDoH in CVD. We searched systematic reviews (with or without meta‐analyses) using 8 databases and included review reference lists. Four themes (economic circumstances, social/community context, early childhood development, and neighbourhood/built environment) and health literacy in the health/health care theme were considered. Seventy reviews were eligible. Despite the quality of the included reviews being low or critically low, there was consistent evidence that factors relating to economic circumstances and early childhood development themes were associated with an increased risk of CVD and CVD mortality. We also found evidence that factors in the social/community context and neighbourhood/built environment themes, such as social isolation, fewer social roles, loneliness, discrimination, ethnicity, neighborhood socioeconomic status, violence, and environmental attributes, had a role in CVD. SDoH factors without (or with minimal) evidence synthesis for CVD were also identified. In sum, this umbrella review offers evidence that SDoH, especially economic circumstance and early childhood development, play a significant role in CVD. This calls for the strengthening of nonmedical interventions that address multiple factors simultaneously and the inclusion of SDoH in future CVD risk prediction models. Registration URL: https://www.crd.york.ac.uk/prospero/ ; Unique identifier: CRD42022346994.

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“…Ten were published by a student with a faculty appointment [34][35][36][37][38][39][40][41][42][43]. Overall, there were 3 case reports [34,44,45], one case series [46], 2 editorials [41,43], 2 letters [37,47], 2 review articles [48,49], 7 systematic reviews [35,36,[38][39][40]42,50], 2 retrospective cohort studies [51,52], an evaluation of mobile health applications [53], and a medical education report. [54] One case report noted the subject's race, without further comment [44].…”

Section: Course Evaluation and Student Publicationsmentioning

confidence: 99%