Incidence and cost of hypoglycemic events requiring medical assistance in a hospital setting in Denmark

Lyngsie, Pavika J; Lopes, Sandra Ribeiro de Almeida; Olsen, Jens

doi:10.2217/cer.15.68

Cited by 7 publications

(3 citation statements)

References 26 publications

(32 reference statements)

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“…Furthermore, this study only assessed costs of hypoglycaemic events that were classified as severe events in our study. Second, some studies were limited to healthcare costs, 8 9 while we also took into account informal care costs and productivity costs. Third, different assumptions were made regarding the incidence of hypoglycaemia: while one study assumed an event rate of 0.09 per patient with T2DM per year (ie, 0.24 in insulin users and 0.04 in patients using oral antidiabetic agents), 6 the incidence among insulin-treated patients with T2DM in our study varied from 571 to 584 events in the 4-week follow-up period (ie, 15.8–16.2 per patient per year).…”

Section: Discussionmentioning

confidence: 99%

A cost of illness study of hypoglycaemic events in insulin-treated diabetes in the Netherlands

et al. 2018

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ObjectivesPatients with diabetes mellitus are at a risk for hypoglycaemia. Besides the burden of hypoglycaemia for patients, hypoglycaemia poses an economic burden to society. The aim of this study was to calculate the per patient societal costs of hypoglycaemia among patients with type1 diabetes (T1DM) and type 2 diabetes (T2DM) on insulin therapy in the Netherlands.MethodsTo calculate the costs of hypoglycaemia, data from the Global Hypoglycaemia Assessment Tool (HAT) study were used. Dutch patients were selected from the HAT study database and data regarding healthcare resource use, informal care use and productivity losses were combined with Dutch unit costs to calculate the per patient 4-week costs of patients experiencing hypoglycaemia. Besides these 4-week costs, costs per hypoglycaemic event were calculated by dividing the study population total 4-week costs by the total number of events in this period.ResultsMean 4-week total costs of hypoglycaemia amounted to €163 (SD, €870) in T1DM and €134 (SD, €364) in T2DM. While productivity costs were the most important cost driver of hypoglycaemia in patients with T1DM (accounting for 72% of the total costs), costs of hypoglycaemia in patients with T2DM were almost entirely driven by costs within the healthcare sector (accounting for 98% of the total costs). Mean costs of a severe hypoglycaemic event were €828 and €508 in T1DM and T2DM, respectively, whereas mean costs of a non-severe event were almost zero.ConclusionsThis study showed that the economic burden of severe hypoglycaemia is substantial. The prevention of hypoglycaemia could therefore not only reduce the burden for patients, but also the economic burden to society.

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Section: Discussionmentioning

confidence: 99%

A cost of illness study of hypoglycaemic events in insulin-treated diabetes in the Netherlands

et al. 2018

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“…5 Hypoglycemia is uncomfortable and tracks with anxiety, in both experimental models 6 and clinical settings. 7,8 Thus, despite strong evidence that tight glycemic control reduces long-term complications of diabetes, such control may have a "dark side", with a substantial number of people with T1D developing an understandable, but ultimately counterproductive, cycle of fear of hypoglycemia (FoH) leading to anxiety, with a consequent reduction in quality of life as well as worsening control and complication rates.…”

mentioning

confidence: 99%

“…Few people with diabetes have lasting ill effects of hypoglycemia on cognitive function, and hypoglycemic encephalopathy appears to occur quite infrequently, but there is no doubt that hypoglycemia is a common, and costly, complication of treatment of type 1 diabetes (T1D) . Hypoglycemia is uncomfortable and tracks with anxiety, in both experimental models and clinical settings .…”

mentioning

confidence: 99%

Fear of hypoglycemia

Bloomgarden

2016

Journal of Diabetes

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Incidence and prevalence of hypoglycaemia in type 1 and type 2 diabetes individuals: A systematic review and meta-analysis

Alwafi

Alsharif

et al. 2020

Diabetes Research and Clinical Practice

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Incidence and cost of hypoglycemic events requiring medical assistance in a hospital setting in Denmark

Abstract: HEs represent a major burden for the Danish healthcare system.

Cited by 7 publications

References 26 publications

A cost of illness study of hypoglycaemic events in insulin-treated diabetes in the Netherlands

A cost of illness study of hypoglycaemic events in insulin-treated diabetes in the Netherlands

Fear of hypoglycemia

Incidence and prevalence of hypoglycaemia in type 1 and type 2 diabetes individuals: A systematic review and meta-analysis

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