In vivo hypoglycemic effects of phenolics from the root bark of Morus alba

Zhang, Mi; Chen, Man; Zhang, Hanqing; Sun, Shi Yong; Xia, Bing; Wu, Feihua

doi:10.1016/j.fitote.2009.06.009

Cited by 95 publications

(51 citation statements)

References 7 publications

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“…The structures of the isolated compounds, identified by physical properties and spectroscopic data, including UV, IR, NMR and MS data and confirmed by comparison with previously reports are as (E)-2,4-dihydroxy-3-(3,7-dimethyl-2,6-octadienyl) benzaldehyde (1) [14], p-hydroxy benzoic acid methyl ester (2) [15], umbelliferone (3) [16], moracin M (4) [17] and trans-resveratrol (5) [18]. Their spectral data are given as follow: 2,4-Dihydroxy-3-(3,7-dimethyl-2 …”

Section: Structure Of Isolated Compoundssupporting

confidence: 83%

Determination of Phytochemical Compounds, and Tyrosinase Inhibitory and Antimicrobial Activities of Bioactive Compounds from <i>Streblus ilicifolius</i> (S Vidal) Corner

Dej-adisai

Parndaeng²,

Wattanapiromsakul³

2016

Trop. J. Pharm Res

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Purpose: To determine the phytochemical content, and tyrosinase inhibitory and antimicrobial activities of the wood from Streblus ilicifolius (S. Vidal) Corner aureus. Phytochemical investigation showed five compounds, namely, (E)-2,4-dihydroxy-3-(3,7-dimethyl-2,6-octadienyl) benzaldehyde (1), phydroxybenzoic acid methyl ester (2), umbelliferone (3), moracin M (4), trans-resveratrol (5). Compound 4 exhibited tyrosinase inhibition with half maximal inhibitory concentration (IC50)

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Section: Structure Of Isolated Compoundssupporting

confidence: 83%

Determination of Phytochemical Compounds, and Tyrosinase Inhibitory and Antimicrobial Activities of Bioactive Compounds from <i>Streblus ilicifolius</i> (S Vidal) Corner

Dej-adisai

Parndaeng²,

Wattanapiromsakul³

2016

Trop. J. Pharm Res

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“…Other groups have reported that moracin M and mullberroside A isolated from MB are hypoglycemic and that puerarin isolated from PR is antihyperglycemic (18,41). DW1029M failed to reduce blood glucose levels; however, DW1029M reduced the level of urinary albumin excretion in STZ-injected rats.…”

Section: Discussionmentioning

confidence: 93%

DW1029M, a novel botanical drug candidate, inhibits advanced glycation end-product formation, rat lens aldose reductase activity, and TGF-β₁signaling

Yoon

Lee

Chang

et al. 2014

American Journal of Physiology-Renal Physiology

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“…These compounds were also able to inhibit protein, tyrosine phosphatase as compared to ursolic acid. 97 In recent years a number of antidiabetic natural products have been discovered. Some of the important anti diabetic compounds have been summarized in Table 2 11…”

Section: Novel Isolated Anti Diabetic Compounds From Plantsmentioning

confidence: 99%

Botanical remedy for diabetes mellitus: Roadmap of last 10 years

Jayendra¹,

Mohanty²

2018

IJCTR

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:The mankind has received a gift from mother-nature in the form of natural laboratories present within diversified plant kingdom. The plants create secondary metabolites for their own safety and many of these secondary metabolites are useful for human beings in various kinds of ailments. Diabetes is not an exception to this, there are many secondary metabolites isolated from plants which are now being utilized for treatment. The significance of isolating metabolites from plants is that they have comparatively very less side effects as compared to allopathic system of medicine (oral hypoglycaemic agents). This review takes into account, the recent updates in the treatment of diabetes mellitus using herbal products and phytochemical constituents reported so far.A total number of 150 plant species belonging to numerous families are presented in this review which is useful in the treatment of diabetes mellitus. Article also contains more than fifty medicinal compounds recently updated in literature. The most important families in present review are fabaceae and cucurbitaceae. The plants from these families are found to be of high therapeutic value to treat diabetes mellitus however families like musaceae, punicaceae and aloaceae have been found to contain least number of effective plant species. The plant parts contributing mostly active compounds are leaves, fruit & seeds.

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In vivo hypoglycemic effects of phenolics from the root bark of Morus alba

Cited by 95 publications

References 7 publications

Determination of Phytochemical Compounds, and Tyrosinase Inhibitory and Antimicrobial Activities of Bioactive Compounds from <i>Streblus ilicifolius</i> (S Vidal) Corner

Determination of Phytochemical Compounds, and Tyrosinase Inhibitory and Antimicrobial Activities of Bioactive Compounds from <i>Streblus ilicifolius</i> (S Vidal) Corner

DW1029M, a novel botanical drug candidate, inhibits advanced glycation end-product formation, rat lens aldose reductase activity, and TGF-β₁signaling

Botanical remedy for diabetes mellitus: Roadmap of last 10 years

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In vivo hypoglycemic effects of phenolics from the root bark of Morus alba

Cited by 95 publications

References 7 publications

Determination of Phytochemical Compounds, and Tyrosinase Inhibitory and Antimicrobial Activities of Bioactive Compounds from <i>Streblus ilicifolius</i> (S Vidal) Corner

Determination of Phytochemical Compounds, and Tyrosinase Inhibitory and Antimicrobial Activities of Bioactive Compounds from <i>Streblus ilicifolius</i> (S Vidal) Corner

DW1029M, a novel botanical drug candidate, inhibits advanced glycation end-product formation, rat lens aldose reductase activity, and TGF-β1signaling

Botanical remedy for diabetes mellitus: Roadmap of last 10 years

Contact Info

Product

Resources

About

DW1029M, a novel botanical drug candidate, inhibits advanced glycation end-product formation, rat lens aldose reductase activity, and TGF-β₁signaling