In vivo Genotoxic Evaluation of Biological and Organic Pesticides and Fertilizers

Toxicity of Bacillus thuringiensis var. israelensis in aqueous suspension on the South American common frog Leptodactylus latrans (Anura: Leptodactylidae) tadpoles

“…However, using grasshoppers (Oxya chinensis) as animal model for chromosome aberration assays, Ren et al (2002) demonstrate genotoxicity of Bt to O. chinensis. In addition, in a genotoxic evaluation through a series of tests in vivo in rodents, including erythrocyte MN assay and bone marrow of chromosomal aberration test, Curbelo Valiente et al (2013) did not find an increase genetic damage. Nevertheless, our results indicate that Bti mixed with inert ingredients of the evaluated commercial formulation is potentially genotoxic.…”

Evaluation of the cytogenetic effects of Quantis biostimulant in Allium sativum cells

“…The biostimulant Quantis has not been tested on animal systems; instead, there are results of other researches carried out with other biological products. Thus, Gluticid, an biological fungicide, was found to be a causative agent of genotoxic and citotoxic effects in somatic cells of female mice at the tested doses (Valiente et al, 2013).…”

“…In spite of the supposed low toxicity of the biological and organic products, an evaluation system to assess its possible damage to humans and environment must be used (Valiente et al, 2013). The biostimulant Quantis has not been tested on animal systems; instead, there are results of other researches carried out with other biological products.…”