“…Assessment of changes to the genetic make-up of aquatic organisms is one of the debilitating effect of chemical contaminants, which is why genotoxicity assessment has been widely investigated globally. 66,73,[141][142][143][144][145][146][147][148][149] Genotoxicity was mainly evaluated by Ames, comet and p53-based reporter assay. However, whole organism assessments for DNA damage were also common.…”