In vivo evaluation of plasma-sprayed wollastonite coating

Xue, Weichang; Liu, Xuanyong; Zheng, Xuebin; Ding, Chuanxian

doi:10.1016/j.biomaterials.2004.09.027

Cited by 222 publications

(139 citation statements)

References 10 publications

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“…Owing to their good bioactivity, CaSiO 3 ceramics have been used as coating on Ti-6Al-4V for biomedical applications (De Aza et al 2000;Liu et al 2004a,b;Xue et al 2005). The results showed enhanced bonding strength of the plasma-sprayed CaSiO 3 coating, compared with HAp (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…Ti-6Al-4V coated with bioactive ceramics such as plasma-sprayed hydroxyapatite (HAp; Ha et al 1998;Harle et al 2006;Balani et al 2007) and calcium silicate (CaSiO 3 ; Liu et al 2001;Xue et al 2005) showed improved stability of Ti-6Al-4V, providing a strong interface between the coating and the alloy and enhanced bone growth and mineralization (Soballe et al 1991). However, these too have drawbacks (Kweh et al 2002;Liu et al 2004a,b;Xue et al 2004).…”

Section: Introductionmentioning

confidence: 99%

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Plasma-sprayed CaTiSiO ₅ ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity

Ramaswamy

Liu

et al. 2008

J. R. Soc. Interface.

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Novel Ca-Si-Ti-based sphene (CaTiSiO 5 ) ceramics possess excellent chemical stability and cytocompatibility. The aim of this study was to prepare sphene coating on titanium alloy (Ti-6Al-4V) for orthopaedic applications using the plasma spray method. The phase composition, surface and interface microstructure, coating thickness, surface roughness and bonding strength of the plasma-sprayed sphene coating were analysed using X-ray diffraction, scanning electron microscopy, atomic force microscopy and the standard mechanical testing of the American Society for Testing and Materials, respectively. The results indicated that sphene coating was obtained with a uniform and dense microstructure at the interface of the Ti-6Al-4V surface and the thickness and surface roughness of the coating were approximately 150 and 10 mm, respectively. Plasma-sprayed sphene coating on Ti-6Al-4V possessed a significantly improved bonding strength and chemical stability compared with plasma-sprayed hydroxyapatite (HAp) coating. Plasma-sprayed sphene coating supported human osteoblast-like cell (HOB) attachment and significantly enhanced HOB proliferation and differentiation compared with plasma-sprayed HAp coating and uncoated Ti-6Al-4V. Taken together, plasma-sprayed sphene coating on Ti-6Al-4V possessed excellent bonding strength, chemical stability and cellular bioactivity, indicating its potential application for orthopaedic implants.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Plasma-sprayed CaTiSiO ₅ ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity

Ramaswamy

Liu

et al. 2008

J. R. Soc. Interface.

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“…After 17 permeabilisation with buffered 0.5% (v/v) Triton X-100 in PBS (300 mM sucrose, 50 mM 18 NaCl, 3 mM MgCl2, 20 mM HEPES and pH 7.2) and blocking with 10 mg ml -1 BSA in PBS, 19 samples were incubated with relevant primary antisera (diluted appropriately using 10 mg ml -20 1 BSA in PBS) at 4 °C overnight. This was followed by 1 h incubation with Alexa Fluor ® 21 488-conjugated secondary antibody.…”

mentioning

confidence: 99%

“…The modal diameter of interconnects of 8 pores was 181 μm for Ak and 160 μm for WD foams, both above 100 m. unindexed peaks could contain Na and/or B, or these could be present in a glass phase around 19 silicate crystals, although the amount of glass would be small (too small to analyse by EDX).…”

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confidence: 99%

Biocompatibility and bioactivity of porous polymer-derived Ca-Mg silicate ceramics

Fiocco

Stevens

et al. 2017

Acta Biomaterialia

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“…31 an additional study showed that when the wollastonite was used in vivo, an apatite layer was formed by which the new bone tissue bonded to the implant. 32 Thence, the chemical fixation of biomaterials to bone tissue and ultimately in vivo success of the bone grafting materials was facilitated. Besides, incorporation of microspheres into scaffolds can abolish the initial burst by a combination of pore diffusion and polymer erosion.…”

Section: Biodegradable Materialsmentioning

confidence: 99%

Recent advances in materials for extended-release antibiotic delivery system

et al. 2011

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To maintain antimicrobial activity, frequent administration of conventional formulations of many antibiotics with short half-life is necessary. Otherwise, concentration under MIC occurs frequently in the course of anti-infective treatment, which induces antibiotic resistance. By maintaining a constant plasma drug concentration over MIC for a prolonged period, extended-release dosage forms maximize the therapeutic effect of antibiotics while minimizing antibiotic resistance. Another undoubted advantage of extended-release formulation is improved patient compliance. For better release properties, many materials have been introduced into the matrix and coating extended-release system in the past few years. Materials that have been widely used in industry are hydrophilic matrix materials such as hydroxypropylmethylcellulose. The excellent biocompatibility and extensive laboratory studies provide biodegradable polymers great potential for industrial applications. In addition, it seems like the researches on tailored materials that are obtained by chemical modification of the existing materials or combination of different carriers in physical mixtures have a long way to go. Meanwhile, with the development of polymers and inorganic porous nanocarriers, nanotechnology is applied increasingly for the extended delivery of antibiotics. This review highlights the development of materials used in extended-release formulation and nanoparticles for antibiotic delivery. We also provide an overview of the antibiotic extended-release products that have provided clinical benefit or are undergoing the clinical trial.

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In vivo evaluation of plasma-sprayed wollastonite coating

Cited by 222 publications

References 10 publications

Plasma-sprayed CaTiSiO ₅ ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity

Plasma-sprayed CaTiSiO ₅ ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity

Biocompatibility and bioactivity of porous polymer-derived Ca-Mg silicate ceramics

Recent advances in materials for extended-release antibiotic delivery system

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In vivo evaluation of plasma-sprayed wollastonite coating

Cited by 222 publications

References 10 publications

Plasma-sprayed CaTiSiO 5 ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity

Plasma-sprayed CaTiSiO 5 ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity

Biocompatibility and bioactivity of porous polymer-derived Ca-Mg silicate ceramics

Recent advances in materials for extended-release antibiotic delivery system

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Plasma-sprayed CaTiSiO ₅ ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity

Plasma-sprayed CaTiSiO ₅ ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity