In vivo evaluation of gelatin/hyaluronic acid nanofiber as Burn-wound healing and its comparison with ChitoHeal gel

Ebrahimi-Hosseinzadeh, Bahman; Pedram, Mir Sepehr; Hatamian-Zarmi, Ashrafalsadat; Salahshour-Kordestani, Soheila; Rasti, M.; Mokhtari-Hosseini, Zahra Beagom; Mir-Derikvand, Mohammad

doi:10.1007/s12221-016-6259-4

Cited by 41 publications

(31 citation statements)

References 30 publications

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“…Przykładowo, Ebrahimi-Hosseinzadeh i współpr. połączyli dwa naturalne polimery: żelatynę i kwas hialuronowy [32]. Wpływ uzyskanego kompozytu na gojenie się ran u szczurów z głębokimi oparzeniami drugiego stopnia porównywano z działaniem komercyj nie stosowanego środka -ChitoHeal.…”

Section: Materiały Opatrunkoweunclassified

“…Wpływ uzyskanego kompozytu na gojenie się ran u szczurów z głębokimi oparzeniami drugiego stopnia porównywano z działaniem komercyj nie stosowanego środka -ChitoHeal. Po 14 dniach za obserwowano, że rana opatrzona kompozytową nanow łókniną zamknęła się w 81,9%, rana opatrzona środkiem ChitoHeal w 77,8%, podczas gdy rana nieopatrzona (gru pa kontrolna) w 65% [32].…”

Section: Materiały Opatrunkoweunclassified

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Electrospun polymer nanofibers for medical applications

Winkler¹,

Maliszewska²,

Czapka³

2020

Polimery

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Streszczenie: Nanowłókna polimerowe wzbudzają obecnie ogromne zainteresowanie ze względu na ich potencjalne wykorzystanie w różnych procesach technologicznych, np. w produkcji tkanin lub wy twarzaniu membran. Włókna te wykazują wyjątkowe właściwości, takie jak: duży stosunek powierzch ni do objętości oraz duża porowatość. Znanych jest kilka metod wytwarzania nanowłókien, jednak ze względu na prostotę, powtarzalność i niewielkie koszty, najpowszechniej stosowane jest przędzenie elektrostatyczne. Przedstawiono przegląd najnowszych osiągnięć w zakresie zastosowań nanowłókien polimerowych w medycynie, obejmujący zagadnienia materiałów opatrunkowych, uwalniania sub stancji aktywnych oraz inżynierii tkankowej.Słowa kluczowe: elektroprzędzenie, nanowłókna, zastosowania medyczne.Abstract: Polymer nanofibers are currently of great interest in terms of their potential use in various technological processes, e.g. in the manufacture of textiles or membranes. These fibers are characterized by extraordinary properties such as high surface to volume ratio and high porosity. There are several methods of manufacturing nanofibers, but for reasons of simplicity, repeatability and low cost, elec trostatic spinning is the most common. The article presents a review of the latest developments in the application of polymer nanofibers in medicine, including such issues as bandage materials, release of active substances and tissue engineering.

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Section: Materiały Opatrunkoweunclassified

Electrospun polymer nanofibers for medical applications

Winkler¹,

Maliszewska²,

Czapka³

2020

Polimery

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“…Recently, in vivo evaluation of gelatin/hyaluronic acid hybrid nanofibers was also evaluated for wound healing purposes in comparison to Chitoheal gel. At the end of the 14th day, it was shown that the nanofibrous scaffold provided improved the wound healing property compared to the gel-based formulation (as shown in Figure 8 ) [ 240 ].…”

Section: Proteinsmentioning

confidence: 99%

“…( B ) The H&E stained section of granulation tissue of control, chitoheal gel and GE/HA nanofibrous scaffold shows that irregular collagen bands that are evident in control are absent in GE/HA nanofibrous scaffold. Reproduced with permission from [ 240 ].…”

Section: Figurementioning

confidence: 99%

Smart Carriers and Nanohealers: A Nanomedical Insight on Natural Polymers

et al. 2017

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Biodegradable polymers are popularly being used in an increasing number of fields in the past few decades. The popularity and favorability of these materials are due to their remarkable properties, enabling a wide range of applications and market requirements to be met. Polymer biodegradable systems are a promising arena of research for targeted and site-specific controlled drug delivery, for developing artificial limbs, 3D porous scaffolds for cellular regeneration or tissue engineering and biosensing applications. Several natural polymers have been identified, blended, functionalized and applied for designing nanoscaffolds and drug carriers as a prerequisite for enumerable bionano technological applications. Apart from these, natural polymers have been well studied and are widely used in material science and industrial fields. The present review explains the prominent features of commonly used natural polymers (polysaccharides and proteins) in various nanomedical applications and reveals the current status of the polymer research in bionanotechnology and science sectors.

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“…There have been a number of studies reported for the preparation of different polymeric nanofibers and incorporation of active agents for improved wound healing performances. Ebrahimi-Hosseinzadeh et al [56] reported preparation of nanofibrous scaffold by blending two natural polymers, namely, GE and HA. In vivo wound healing study in Wistar rats with deep second-degree burns has been investigated in comparison with ChitoHeal gel (a commercial wound dressing).…”

Section: Composite Polymer Nanofibers As Wound Healing Scaffoldsmentioning

confidence: 99%