In vivo antimutagenic effects of the Barbados cherry fruit (Malpighia glabra Linnaeus) in a chromosomal aberration assay

Düsman, Elisângela; Almeida, Igor Vivian de; Tonin, Lilian Tatiani Düsman; Vicentini, Verônica Elisa Pimenta

doi:10.4238/gmr15049036

Cited by 6 publications

(2 citation statements)

References 25 publications

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“…Plants extracts belonging to the Malpighiaceae family also present other potential pharmacological properties, such as antimicrobial, wound healing and antitumor (Düsman et al 2016, Specian et al 2016.…”

Section: Discussionmentioning

confidence: 99%

Saline extract from Malpighia emarginata DC leaves showed higher polyphenol presence, antioxidant and antifungal activity and promoted cell proliferation in mice splenocytes.

Barros

Barboza

Ramos

et al. 2019

An. Acad. Bras. Ciênc.

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Currently, the research of new natural compounds with biological potential demonstrates great ethnopharmacological importance. In this study, we evaluated the biological properties promoted by saline extract from Malpighia emarginata DC leaves, whose objective is to evaluate the antioxidant, antimicrobial and cytotoxicity potential. Phytochemical characterization was performed by UPlC-MS chromatography to identify the chemical compounds. For the antioxidant potential, DPPH, ATT and FRAP methods were used. The antibacterial and antifungal tests were performed evaluating the MIC50, MIC90, CMB and CMF parameters. Moreover, antibiofilm action was evaluated. Cytotoxicity and proliferation were performed using splenocytes from Balb/c mice and were evaluated by cytometry. We found a list of phenolic compounds among other bioactive compounds in the M. emarginata saline extract. In addition, higher antioxidant profile and antifungal activity against different strains of Candida spp. was promoted by the saline extract. Splenocytes showed greater cell viability (more than 90%) and showed higher proliferate index in 24 and 48 hours of incubation with the extract. Saline extract from Malpighia emarginata DC has potential action like antioxidant and antifungal agent without promote animal cell damage.

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Section: Discussionmentioning

confidence: 99%

Saline extract from Malpighia emarginata DC leaves showed higher polyphenol presence, antioxidant and antifungal activity and promoted cell proliferation in mice splenocytes.

Barros

Barboza

Ramos

et al. 2019

An. Acad. Bras. Ciênc.

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show abstract

“…Os resultados justificam o uso adicional das misturas para enriquecimento de produtos para prevenção de doenças crônicas. É demonstrado em pesquisas diversas atividades biológicas como: atividade antioxidante, antimutagênica, antidiabética, antitumoral e hepatoprotetora (Paz et al, 2015;Düsman, Almeida, Tonin, & Vicentini, 2016;Barbalho et al, 2011;Luveena, Karthiayini, & Sreekumar, 2012).…”

Section: Acerola (Malpighia Spp)unclassified

Viabilidade da obtenção de polpa de acerola (malpighia spp) microencapsulada e liofilizada: Uma revisão

Saqueti

Alves

Ponhozi

et al. 2021

RSD

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O objetivo desta revisão é fornecer uma compreensão profunda das técnicas que induzem os processamentos de qualidade da acerola e preservação de seus compostos bioativos. Foi possível concluir que a acerola é um fruto com grande potencial antioxidante, devido seus compostos bioativos, sendo necessário a aplicação de tecnologias como a microencapsulação e liofilização para conservação dos mesmos. Novos estudos se tornam necessários para a avaliação do comportamento da polpa de acerola em diferentes parâmetros de aplicação, além da realização de analises físico-química, “in vitro” e “in vivo”.

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Grape Bagasse Extracts: Antioxidant and Cytotoxic Activity in HTC Cells

Rocha

Viega

Fontana

et al. 2023

Waste Biomass Valor

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In vivo antimutagenic effects of the Barbados cherry fruit (Malpighia glabra Linnaeus) in a chromosomal aberration assay

Cited by 6 publications

References 25 publications

Saline extract from Malpighia emarginata DC leaves showed higher polyphenol presence, antioxidant and antifungal activity and promoted cell proliferation in mice splenocytes.

Saline extract from Malpighia emarginata DC leaves showed higher polyphenol presence, antioxidant and antifungal activity and promoted cell proliferation in mice splenocytes.

Viabilidade da obtenção de polpa de acerola (malpighia spp) microencapsulada e liofilizada: Uma revisão

Grape Bagasse Extracts: Antioxidant and Cytotoxic Activity in HTC Cells

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