In-vitro-Untersuchung unterschiedlicher PMMA-Knochenzemente - ein erster Vergleich neuer Materialien für die Endoprothetik

Abstract

In view of these differences in material properties, the clinical data from long-term use of the bone cements Refobacin Palacos R and Palacos R + G cannot be extrapolated to the newly developed PMMA cements Refobacin Bone Cement R and Smart GHV. Before broad clinical use of these cements, prospective clinical studies using RSA or DEXA and, as a second step, statistically powerful prospective comparative studies should be performed. Until these data are available, patients in whom Refobacin Bone Cement R and SmartSet GHV are used should be informed that the material employed deviates from the standard procedures for cemented joint replacement in the Scandinavian arthroplasty registers and that the long-term consequences cannot, in the final instance, be foreseen. This is essential in order to avoid later malpractice claims on the grounds of inadequate information.

Bone cement product and failure in total knee arthroplasty

“…(2008) conducted in vitro tests of different properties between the "Palacos" cements Refobacin Palacos R and Palacos R + G and the bone cements SmartSet GHV and Refobacin BCR. Their study included handling properties, chemical analysis, and testing according to the ISO standard for acrylic bone cements.…”

Revision of tibial TKA components: bone loss is independent of cementing type and technique: an in vitro cadaver study

“…Fully cemented stems were more difficult to remove during revision and were accompanied by increased bone loss in the metaphyseal area. Furthermore, the type of bone cement appeared to be important for long-term stability of the implant [6]. …”

“…In vitro studies demonstrated a significant influence of penetration on the initial component stability in TKA [11,22,23]. Limited experimental and clinical data exist for the material properties of the Refobacin ® Bone Cement R. Kock et al [6] compared the chemical composition, handling properties, and ISO standard mechanical testing of four different bone cements in vitro. Chemical analysis showed that the copolymers in Refobacin ® Bone Cement R differed from the Palacos ® cements.…”

“…To provide stable implant fixation and to reestablish the correct joint line bony defects can be treated with cement, modular augments, custom-made implants, and bone grafts [3-5]. Bone cements of different manufacturers have the same functional principles but have differences in chemical composition [6] which can effect their material properties. The varying viscosity of bone cements can lead to different depths of intrusion.…”

Biomaterials in skull base surgery

“…With respect to stability, however, great differences have been observed between various products and manufacturers of PMMA cement [46]. In principle, PMMA-based implants can also be preformed (see Neumann, Chap.…”