In-Vitro Studies on Antitumour and Antimicrobial Activities of Methanolic Kernel Extract of Mangifera Indica L. Cultivar Banganapalli

Raju, Nadakuditi Venkata; Sukumar, Karuganti; Reddy, G. Babul; Pankaj, P. K.; Muralitharan, Gangatharan; Annapareddy, Shanti; Rao, Yakkala Revanth Subramanyam Sai*, Dr Ch. Prasad, Dr T.K.V. Kesav; Chintagunta, Anjani Devi

doi:10.13005/bpj/1648

Cited by 14 publications

(5 citation statements)

References 24 publications

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“…In the year 2016-2017, the total estimated area under guava cultivation was 2,61,700 hectares (ha) with the production of 36,48,200 million tons (MT) (Horticultural Statistics at a Glance 2017). Guava is considered as multipurpose medicinal tree similar to Mangifera indica and Azadirachta indica because of myriad medicinal values from various parts viz., leaf, roots, bark and fruit (Sravani et al 2015;Naidu et al 2016;Raju et al 2019). The leaf extract of guava has pharmacological activity (Uzzaman et al 2018) due to the presence of bioactive compounds that treat dysentery, diarrhoea, flatulence, gastric problems and regulate blood glucose levels.…”

Section: Introductionmentioning

confidence: 99%

Extraction of bioactive compounds from Psidium guajava and their application in dentistry

et al. 2019

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Guava is considered as poor man's apple rich in phytochemicals with medicinal value and hence it is highly consumed. Gas chromatography-mass spectroscopy (GC-MS) analysis of guava leaf extract revealed the presence of various bioactive compounds with antimicrobial, antioxidant, anticancer, and antitumor properties. Hence, it is used in tooth paste formulations along with other ingredients such as Acacia arabica gum powder, stevia herb powder, sea salt, extra virgin coconut oil, peppermint oil in the present study. Three formulations F1, F2 and F3 have been made by varying the concentration of these ingredients and the prepared formulations were studied for their antimicrobial activity and physico-chemical parameters such as pH, abrasiveness, foaming activity, spreading and cleaning ability. Among these, F3 showed significant antioxidant and antimicrobial properties, minimal cytotoxicity, maximum spreadability and very high cleaning ability. This study surmises that the herbal toothpaste formulation is greener, rich in medicinal values and imparts oral hygiene.

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Section: Introductionmentioning

confidence: 99%

Extraction of bioactive compounds from Psidium guajava and their application in dentistry

et al. 2019

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“…Studies have reported that M. indica kernel extract showed good antimicrobial activity when used as a methanolic preparation; hence, a similar preparation was used in the present study [ 15 , 16 ]. It was considered not to exceed the acute toxic dose of M. indica kernel extract [ 17 ]; hence, 50 and 40 μ l of M. indica kernel extract were used to test the herbal agents.…”

Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Antimicrobial and Smear Layer Removal Efficacy of Mangifera indica Kernel Extract as Root Canal Irrigant in Primary Molar: An In Vitro Study

Haripriya,

Farzan,

Baghkomeh

et al. 2024

International Journal of Dentistry

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Background. Endodontic therapy aims to disinfect the entire root canal system. Extracts from the kernel of Mangifera indica has the potential to be a novel root canal irrigant that has yet to be studied. Hence, the present study evaluated the antimicrobial, and smear layer removal efficacy of the M. indica kernel extract as a root canal irrigant in primary molars. Materials and Methods. Methanolic extract of M. indica was prepared using the standard method. The antimicrobial efficacy of M. indica kernel extract was determined by agar diffusion method with 3% sodium hypochlorite and distilled water as controls, and the smear layer removal efficacy was assessed under the SEM after processing the root samples with different concentrations of M. indica kernel extract with 17% EDTA and distilled water as positive and negative controls, respectively. Results. A statistically significant antimicrobial efficacy was observed with the largest mean zone of inhibition recorded with 50 μl of M. indica kernel extract at 24 hr of incubation period, when compared to sodium hypochlorite as a root canal irrigant against Enterococcus faecalis using agar diffusion method at MIC value of 0.625 mg/ml. The smear layer removal efficacy of the M. indica kernel extract was not satisfactory, when compared with EDTA as a root canal irrigant in primary molars and observed under SEM. In contrast, a complete smear layer removal was observed with 17% EDTA solution. Conclusion. M. indica kernel extract has an enhanced antimicrobial efficacy but poor smear layer removal efficacy when used as a root canal irrigant.

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“…Anti-inflamatória e antioxidante (Khumpook et al 2019); antitumoral e antimicrobiana (Raju et al 2019).…”

Section: Diarreia E Estômagounclassified

Plantas medicinais, usos e memória na Aldeia do Cajueiro, Pará

Silva

Conceição

Gois

et al. 2020

G. Sci.

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Quintais tradicionais na Amazônia representam fontes de recursos naturais terapêuticos e expressam conhecimentos relacionados a cultura local. Realizou-se um estudo etnobotânico sobre usos e memória com plantas medicinais na Aldeia Indígena do Cajueiro, município de Paragominas, Pará. Os dados foram obtidos por meio de observação não participante e entrevistas semiestruturadas com especialistas locais, selecionados por seleção racional. A partir das entrevistas foi calculado valor de importância das espécies segundo cada especialista. Trabalhou-se com a História Oral para estimular a busca pela memória de uso e os conhecimentos ainda preservados com a medicina tradicional. Identificaram-se 39 espécies, distribuídas em 22 famílias botânicas. As espécies que obtiveram o maior valor de importância foram caju (Anacardium occidentale L.), manga (Mangifera indica L.), seguidas com pariri (Fridericia chica (Bonpl.) L.G.Lohmann), cidreira (Lippia alba (Mill) N. E. Brown.), capim santo (Cymbopogon citratus (DC.) Stapf). As plantas existentes apenas na memória de alguns dos moradores trouxe a tona fragilidades na transmissão de informações bioculturais entre os membros da comunidade. Modificações nas formas de vida, alteração da paisagem e abandono de práticas tradicionais têm prejudicado o compartilhamento de saberes entre especialistas e moradores.

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In-Vitro Studies on Antitumour and Antimicrobial Activities of Methanolic Kernel Extract of Mangifera Indica L. Cultivar Banganapalli

Cited by 14 publications

References 24 publications

Extraction of bioactive compounds from Psidium guajava and their application in dentistry

Extraction of bioactive compounds from Psidium guajava and their application in dentistry

Comparative Evaluation of Antimicrobial and Smear Layer Removal Efficacy of Mangifera indica Kernel Extract as Root Canal Irrigant in Primary Molar: An In Vitro Study

Plantas medicinais, usos e memória na Aldeia do Cajueiro, Pará

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