Extraction of bioactive compounds from Psidium guajava and their application in dentistry

Shaheena, Shaik; Chintagunta, Anjani Devi; Dirisala, Vijaya R.; Kumar, N. S. Sampath

doi:10.1186/s13568-019-0935-x

Cited by 45 publications

(28 citation statements)

References 13 publications

(13 reference statements)

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“…Lignocellulosics are considered among the most promising alternatives to fossil resources ( Keegan et al, 2013 ; Shaheena et al, 2019 ), as they are generated from available atmospheric CO 2 , water, and sunlight through biological photosynthesis. They are sustainable sources of organic carbon and account for excess of 90% of worldwide plant biomass, corresponding to annual biomass of approximately 200 × 10 9 tons ( Kuhad and Singh, 1993 ).…”

Section: Lignocellulosics and Their Potential For Biodiesel Productionmentioning

confidence: 99%

Biodiesel Production From Lignocellulosic Biomass Using Oleaginous Microbes: Prospects for Integrated Biofuel Production

et al. 2021

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Biodiesel is an eco-friendly, renewable, and potential liquid biofuel mitigating greenhouse gas emissions. Biodiesel has been produced initially from vegetable oils, non-edible oils, and waste oils. However, these feedstocks have several disadvantages such as requirement of land and labor and remain expensive. Similarly, in reference to waste oils, the feedstock content is succinct in supply and unable to meet the demand. Recent studies demonstrated utilization of lignocellulosic substrates for biodiesel production using oleaginous microorganisms. These microbes accumulate higher lipid content under stress conditions, whose lipid composition is similar to vegetable oils. In this paper, feedstocks used for biodiesel production such as vegetable oils, non-edible oils, oleaginous microalgae, fungi, yeast, and bacteria have been illustrated. Thereafter, steps enumerated in biodiesel production from lignocellulosic substrates through pretreatment, saccharification and oleaginous microbe-mediated fermentation, lipid extraction, transesterification, and purification of biodiesel are discussed. Besides, the importance of metabolic engineering in ensuring biofuels and biorefinery and a brief note on integration of liquid biofuels have been included that have significant importance in terms of circular economy aspects.

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Section: Lignocellulosics and Their Potential For Biodiesel Productionmentioning

confidence: 99%

Biodiesel Production From Lignocellulosic Biomass Using Oleaginous Microbes: Prospects for Integrated Biofuel Production

et al. 2021

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“…The mixture was incubation in the dark for 30 min and absorbance was measured at 517 nm. Ascorbic acid was used as standard and blank was prepared using methanol (Shaheena et al 2019).…”

Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

Purification and Characterization of Bioactive Compounds Extracted from Suaeda Maritima Leaf and its Impact on Pathogenicity of Pseudomonas Aeruginosa in Catla Catla Fingerlings

Beulah

Divya

Sampath

et al. 2021

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Incidence of various dreadful microbial infections and the development of antibiotic resistance by infection causative microbes are the main reasons for reducing aquaculture productivity. Hence, there is an immense need for the discovery of alternative and efficient treatment for quick recovery of diseased fishes. In the present study, Suaeda maritima leaf extracts (hexane, diethyl ether, ethanol, and water) were screened for in vitro and in vivo antibacterial and antioxidant activities. Out of all the four extracts, ethanolic extract showed highest antibacterial activity against S.aureus (4.9±1.3 mm), B.subtilis (1.6±0.3 mm), K.pneumonia (4.2±1.8 mm), and P.aeruginosa (4.1±1.2 mm). Similarly, antioxidant activity was also higher for ethanolic extract (500 µg/ml) based on DPPH radical scavenging ability (71.6±1.4 %) and reducing potential (149 μg/mL) assays. Further, ethanolic extract was purified consecutively via column chromatography and preparative TLC where an active fraction was selected based on highest antibacterial (10.1±1.4 mm) and antioxidant properties (82.3±2.8 %). Active fraction was loaded onto mass spectroscopy and identified the presence of four active constituents such as 1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-3-yl) methanol; 3',7-Dimethoxy-3-hydroxyflavone; Saponin and (19R)9acetyl19hydroxy10,14dimethyl20oxopentacyclo[11.8.0.0<2,10>.0<4,9>.0<14,19>]henicos-17-yl-acetate. Besides, in vivo studies were conducted on Catla catla fingerlings infected with P. aeruginosa under laboratory conditions. The fingerlings were segregated into 5 groups, among which group 4 and 5 were treated with crude and purified extracts. Both the extracts were efficient in treating infected fingerlings and recorded 100% survival rate which is even better than group-3 treated with a synthetic antibiotic (77%). Hence, S. maritima leaf extract can be considered as a possible alternative medicine in aquaculture

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“…It is rich in phenolics, flavonoids, triterpenoids, tannins, vitamins, essential oils and sesquiterpene alcohols (Altemimi et al 2017 ; Singh et al 2019 ). Guava leaves mainly constitute rutin, naringenin, gallic acid, catechin, epicatechin, kaempferol, isoflavonoids, and flavonoids such as quercetin and guaijaverin that are well known for their antimicrobial, antioxidant and anti-inflammatory actions (Gutiérrez-Grijalva et al 2018 ; Shaheena et al 2019 ). Due to the copious benefits, guava is cultivated worldwide where, India stands in the first position with the production of 40,54,000 million tons (MT) from 2,65,000 hectares (ha) in the year 2017–18 (Horticultural Statistics at a Glance 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Extraction of bioactive compounds from Psidium guajava leaves and its utilization in preparation of jellies

et al. 2021

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Psidium guajava L. (guava) is predominantly grown throughout the world and known for its medicinal properties in treating various diseases and disorders. The present work focuses on aqueous extraction of bioactive compounds from the guava leaf and its utilization in the formulation of jelly to improve the public health. The guava leaf extract has been used in the preparation of jelly with pectin (1.5 g), sugar (28 g) and lemon juice (2 mL). The prepared guava leaf extract jelly (GJ) and the control jelly (CJ, without extract) were subjected to proximate, nutritional and textural analyses besides determination of antioxidant and antimicrobial activities. GJ was found to contain carbohydrate (45.78 g/100 g), protein (3.0 g/100 g), vitamin C (6.15 mg/100 g), vitamin B3 (2.90 mg/100 g) and energy (120.6 kcal). Further, the texture analysis of CJ and GJ indicated that both the jellies showed similar properties emphasizing that the addition of guava leaf extract does not bring any change in the texture properties of jelly. GJ exhibited antimicrobial activity against various bacteria ranging from 11.4 to 13.6 mm. Similarly, GJ showed antioxidant activity of 42.38% against DPPH radical and 33.45% against hydroxyl radical. Mass spectroscopic analysis of aqueous extract confirmed the presence of esculin, quercetin, gallocatechin, 3-sinapoylquinic acid, gallic acid, citric acid and ellagic acid which are responsible for antioxidant and antimicrobial properties.

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Extraction of bioactive compounds from Psidium guajava and their application in dentistry

Cited by 45 publications

References 13 publications

Biodiesel Production From Lignocellulosic Biomass Using Oleaginous Microbes: Prospects for Integrated Biofuel Production

Biodiesel Production From Lignocellulosic Biomass Using Oleaginous Microbes: Prospects for Integrated Biofuel Production

Purification and Characterization of Bioactive Compounds Extracted from Suaeda Maritima Leaf and its Impact on Pathogenicity of Pseudomonas Aeruginosa in Catla Catla Fingerlings

Extraction of bioactive compounds from Psidium guajava leaves and its utilization in preparation of jellies

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