“…griseus. [8,9] Sequencea lignment with someo ther aminotransferases (Figure S1 in the Supporting Information) showedt hat the amino acids important for the formation of the tertiarya nd the quaternary structure of the protein (determined by protein BLAST against conservedd omains) are highly conserved among all these proteins. Thus, the PLP-binding site of ThdN might be formed by G115, S116, G117, F141, N189,Y 219, T245, S247, K248, and R256, with K248 as the catalytic residue, whereas G118, S151, V212, G254, L255, R256, and G283 seem to constitute the homodimer interface.…”