Abstract:Motivation:Indoles have been shown to play a significant role in cardiometabolic disorders.While some individual bacterial species are known to produce indole-adducts, to our best knowledge no studies have made use of publicly available genome data to identify prokaryotes, specifically those associated with the human gut microbiota, contributing to the indole metabolic network.Results: Here, we propose a computational strategy, comprising the integration of KEGG and BLAST, to identify prokaryote-specific metab… Show more
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