In vitro prospective effects of various traditional herbal coffees consumed in Anatolia linked to neurodegeneration

Chemical characterisation and the anti-inflammatory, anti-angiogenic and antibacterial properties of date fruit (Phoenix dactylifera L.)

“…In Palestine, consumption of 3-4 date fruits daily is 362 administered for memory increase (Daoud, 2008). "Hurma coffee" from date 363 fruit seeds is an herbal coffee consumed in Turkey for memory enhancing 364 purpose (Sekeroglu et al 2012). In Mauritius a decoction of a cup of date 365 leaves consumed for 1 week to reduce hyperglycemia (Mootoosamy and 366 …”

Simulated gastrointestinal digestion and in vitro colonic fermentation of date (Phoenix dactylifera L.) seed polyphenols

“…The same authors as well as Sekeroglu et al . () reported the absence of caffeine in DSP. In addition, food products with enhanced level of polyphenols and dietary fibre have been developed in laboratory scale by incorporating DSP.…”

Characterization of Date (Deglet Nour) Seed Free and Bound Polyphenols by High‐Performance Liquid Chromatography‐Mass Spectrometry

“…Date palm is highly valued for its nutritious fruit, while date seeds have been identified as a valuable by‐product of the well‐established date fruit industry (Besbes and others ; Gullon and others ). Date seed infusions (date seed coffee) have been consumed in Middle Eastern countries (Sekeroglu and others ), while hot‐drinks made from roasted or unroasted date seed powders are produced commercially and marketed as a caffeine‐free product. Various studies have shown that date seed extracts from many date varieties contain high amounts of polyphenols with significant antioxidant activity (Ali‐Mohamed and Khamis ; Al‐Farsi and Lee ).…”

“…Additionally, both in‐vitro and in‐vivo studies have shown that date seed extracts show a number of biological activities which can be beneficial to human health. For example, Sekeroglu and others () reported that date seeds extract significantly inhibited acetylcholinesterase and butyrylcholinesterase activities in vitro , which are critical enzymes linked to the development of dementia and Alzheimer's diseases. In another study by Takaeidi and others (), methanolic date seed extract was found to promote the serum antioxidant enzyme paraoxonase (PON1) activity in rats fed with normal and hypercholesterolemic diets.…”