In vitro photoprotective, hemostatic, anti-inflammatory and antioxidant activities of the species Linaria scariosa Desf.

Mouffouk, Chaima; Mouffouk, Soumia; Oulmi, Kafia; Mouffouk, Sara; Haba, Hamada

doi:10.1016/j.sajb.2020.01.003

Cited by 19 publications

(7 citation statements)

References 28 publications

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“…The results of in vitro anti-inflammatory activity showed an excellent ability of this plant extract to maintain the three-dimensional structure of proteins. These findings are in agreement with the results obtained for diclofenac, whichis used as a standard by Mouffouk et al (2020) [69] and possesses an important anti-inflammatory effect (inhibition = 86.72%) at the same concentration as that in which A. gombiformis extract was tested (500 ug/mL). A good correlation was obtained between phenolic compounds and flavonoids identified previously via the LC-ESI-MS technique and anti-inflammatory activity.…”

Section: Discussionsupporting

confidence: 93%

Investigation of Photoprotective, Anti-Inflammatory, Antioxidant Capacities and LC–ESI–MS Phenolic Profile of Astragalus gombiformis Pomel

Lekmine

Boussekine

Akkal

et al. 2021

Foods

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Plant-derived compounds have recently been gaining popularity as skincare factors due to their ability to absorb ultraviolet radiations and their anti-inflammatory, and antioxidant properties. In this light, this work aimed to evaluate in vitro the pharmacological activities of the butanolic extract prepared from the aerial parts of Astragalus gombiformis Pomel, an endemic species to southern Algeria. The sun protection factor was used to assess the photoprotective effect (SPF), the protein denaturation method to determine the anti-inflammatory activity, and brine shrimp nauplii and OxHLIA assay, respectively, to assess the cytotoxicity and antioxidant capacity of A. gombiformis. In addition, LC–ESI–MS analysis was employed for the characterization of the phenolic constituents of A. gombiformis. The results showed that A. gombiformis had high capacity for absorbing UV radiations with an SPF of 37.78 ± 0.85 and significant anti-inflammatory activity with a percentage inhibition of 75.38% which is close to that of diclofenac and ketoprofen. In addition, A. gombiformis was found to have effective cytotoxicity against Artemia nauplii with a DC50 value of about 44.7 µg/mL, but a weak hemolytic effect against human erythrocytes. LC–ESI–MS results detected the presence of 17 phenolic compounds with a predominance of cirsiliol, silymarin, quercitrin (quercetin-3-O-rhamnoside), and kaempferol. Taken together, these results suggest that A. gombiformis extract could be used as a skincare agent in cosmetic formulations, providing excellent antioxidant and anti-inflammatory protection, allowing the treatment of skin conditions, as well as a pharmaceutical agent with multidimensional applications.

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Section: Discussionsupporting

confidence: 93%

Investigation of Photoprotective, Anti-Inflammatory, Antioxidant Capacities and LC–ESI–MS Phenolic Profile of Astragalus gombiformis Pomel

Lekmine

Boussekine

Akkal

et al. 2021

Foods

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“…This is related with a previous report that demonstrated the significant photoprotective effect of flavonoids in UV-B and UV-A range [1]. The protective factor of Ba-BuOH fraction (SPF=14.70±0.11) is higher than that of Ba-MeOH crude extract (8.20±0.22), indeed the higher SPF (290-320) value of Ba-BuOH is probably linked to its phenol and flavonoid contents, which is correlate well with several authors who demonstrated that the photoprotective effect is mainly associated with the levels of phenolics and flavonoids in plant extracts [33][34][35][36][37][38]. [23].…”

Section: Figure 4 Uv-absorbing Profile Of B Alpinumsupporting

confidence: 85%

Highlighting the Cosmeceutical Potential of the Edible Bunium alpinum Waldst& Kit (Apiaceae) Growing in Algeria: in vitro Antioxidant and Photoprotective Effects

Lefahal

Makhloufi

Ayad

et al. 2023

Gazi University Journal of Science

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“…Biological proteins lose their functionality when they are denatured ( Joshi et al, 2020 ). As a result, any agent that can prevent protein denaturation could significantly reduce inflammation ( Mouffouk et al, 2020 ). Several anti-inflammatory drugs, in varying degrees, suppress heat protein denaturation.…”

Section: Discussionmentioning

confidence: 99%

Anti-cholinesterase, anti-inflammatory and antioxidant properties of Combretum micranthum G. Don: Potential implications in neurodegenerative disease

Kpemissi

Kantati

Veerapur

et al. 2023

IBRO Neuroscience Reports

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In vitro photoprotective, hemostatic, anti-inflammatory and antioxidant activities of the species Linaria scariosa Desf.

Cited by 19 publications

References 28 publications

Investigation of Photoprotective, Anti-Inflammatory, Antioxidant Capacities and LC–ESI–MS Phenolic Profile of Astragalus gombiformis Pomel

Investigation of Photoprotective, Anti-Inflammatory, Antioxidant Capacities and LC–ESI–MS Phenolic Profile of Astragalus gombiformis Pomel

Highlighting the Cosmeceutical Potential of the Edible Bunium alpinum Waldst& Kit (Apiaceae) Growing in Algeria: in vitro Antioxidant and Photoprotective Effects

Anti-cholinesterase, anti-inflammatory and antioxidant properties of Combretum micranthum G. Don: Potential implications in neurodegenerative disease

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