In vitro photoprotective effects of Marcetia taxifolia ethanolic extract and its potential for sunscreen formulations

Costa, Sônia Carine Cova; Detoni, Chaline; Branco, Carla Rodrigues Cardoso; Botura, Mariana Borges; Branco, Alexsandro

doi:10.1016/j.bjp.2015.07.013

Cited by 45 publications

(32 citation statements)

References 21 publications

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“…The ethyl acetate extract showed the lowest SPF value as 11.656±0.001. SPF values of methanol and ethanol extract are comparatively higher than reported in previous studies (Costa et al, 2015;Gajardo, 2016;Gonçalves et al, 2015;Napagoda et al, 2016). Whereas, SPF value obtained from hexane, chloroform and ethyl acetate had never been reported before.…”

Section: Preliminary Phytochemical Screeningcontrasting

confidence: 51%

“…Whereas, SPF value obtained from hexane, chloroform and ethyl acetate had never been reported before. According to the guidelines of international regulatory agencies, only SPF value equal or greater than 6 is suitable for use in cosmetic products (Costa et al, 2015). Hence, the results suggested that the G. pictum extract can be considered as a promising active ingredient because of its high SPF value in low concentration (200µg/ml).…”

Section: Preliminary Phytochemical Screeningmentioning

confidence: 86%

“…Hence, the results suggested that the G. pictum extract can be considered as a promising active ingredient because of its high SPF value in low concentration (200µg/ml). If higher SPF is required for formulation, it can be achieved by reducing the dilution factor when preparing the G. pictum extract because SPF is found to be concentration-dependent (Costa et al, 2015). One of the most important factors affecting the extraction efficiency of bioactive compounds from plant materials and their consequent health benefits is the extraction solvent ( Van et al, 2017).…”

Section: Preliminary Phytochemical Screeningmentioning

confidence: 99%

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In vitro evaluation of photoprotective potential of the different solvent extracts of Graptophyllum pictum leaves

2018

J App Pharm Sci

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Natural substances extracted from plants have been gaining attraction as protective agents due to their safety and responsible for multiple biological effects on skins. The present work evaluates the photoprotective potential of different solvent extracts of Graptophyllum pictum (G pictum) leaves, and the comparison of its Sun Protection Factor (SPF) value against photo-stability and thermal-stability under a 21-day of storage process. Preliminary phytochemical screening was also performed. The dried powdered leaves were extracted by cold maceration method, using five different solvent, i.e. methanol, ethanol, chloroform, ethyl acetate and hexane. The SPF of all extracts were analyzed by ultraviolet (UV) spectrophometry. The SPF results of the five types of extracts were found to have significant differences (P < 0.001). Methanol extract displayed the highest SPF value (15.303±0.045), while the lowest SPF value was showed by ethyl acetate extract. SPF reductions of all extracts under sun exposure condition were higher compared to the extracts placed in dark conditions at room temperature. As compared, the ethanol extract displayed better chemical and thermo-stability with higher in vitro SPF at 200 µg/ml. These findings suggested that ethanol was the solvent of choice for yielding high levels of photoprotective ingredients from G. pictum which can be used to formulate effective sunscreen preparations.

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Section: Preliminary Phytochemical Screeningcontrasting

confidence: 51%

Section: Preliminary Phytochemical Screeningmentioning

confidence: 86%

Section: Preliminary Phytochemical Screeningmentioning

confidence: 99%

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In vitro evaluation of photoprotective potential of the different solvent extracts of Graptophyllum pictum leaves

2018

J App Pharm Sci

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“…They also led to the generation of reactive oxygen species (ROS) [ 10 ]. Thus, protecting human skin against UV radiation is evident and the effective protection results in the use of formulations containing solar filters (chemicals that absorb UV radiations) known as sunscreens [ 11 ]. Recently, plant extracts with antioxidant properties have been used in phytocosmetic field to be used as sunscreens.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Assessment of Total Phenolic and Flavonoid Contents, Antioxidant and Photoprotective Activities of Crude Methanolic Extract of Aerial Parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria

et al. 2018

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Background: Capnophyllum peregrinum (L.) Lange (Apiaceae) is the unique taxon of capnophyllum genus in Algerian flora. It has never been investigated in regards to its total phenolic and flavonoid contents and antioxidant and photoprotective activities. Methods: C. peregrinum aerial parts extracted with absolute methanol. The total flavonoid and phenolic contents of the extract were evaluated to determine their correlation with the antioxidant and photoprotective activities of the extract. Results: The methanolic extract demonstrated a significant amount of phenolics and flavonoids (74.06 ± 1.23 mg GAE/g, 44.09 ± 2.13 mg QE/g, respectively) and exhibited good antioxidant activity in different systems, especially in 1,1-Diphenyl-2-picrylhydrazyl (DPPH), reducing power and total antioxidant capacity assays. Furthermore the extract showed high photoprotective activity with the sun protection factor (SPF) value = 35.21 ± 0.18. Conclusions: The results of the present study show, that the methanolic extract could be used as a natural sunscreen in pharmaceutics or cosmetic formulations and as a valuable source of natural antioxidants.

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“…Apple peels contain the flavonoid quercetin and polyphenol derivates, which have antioxidant potential. The polyphenol compounds contained in apple peel are quercetin glycosides, catechin, epicatechin, procyanidin, phloridzin, phloretin glycoside, and chlorogenic acid [9].…”

Section: Introductionmentioning

confidence: 99%

Transfersome Gel Formulation of an Ethanol Extract of Apples (Malus Domestica Mill) Containing Antioxidants and in Vitro Penetration Testing Using Franz Diffusion Cells

Zesiorani

Anwar

2017

Int J App Pharm

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Objective: This study aims to formulate and characterize a transfersome apple peel extract, formulate it into a gel, and compare it with a control gel made without transfersome.Methods: Both gels were evaluated, stability tested, and penetration tested using Franz diffusion cells on the skin of female Sprague-Dawley rats. The transfersome preparations were formulated with different concentrations of the active substance, quercetin: 0.5% (F1); 0.7% (F2), and 1.0% (F3).Results: Based on the characterization results, F1 was selected as the optimum gel formulation because it had spherical morphology, a D mean volume of 106.44±2.70 nm, a polydispersity index of 0.078±0.01, a zeta potential of −49.96±2.05 mV, and a drug efficiency entrapment percentage of 78.78±0.46%. The cumulative amount of quercetin that was penetrated with the transfersome gel was 1514.41±26.31 µg/cm 2 , whereas the penetration with the control gel extract was 1133.62±18.96 µg/cm 2 . The cumulative percentages of the penetrated gel transfersome and gel extract were 78.40±1.89% and 49.89±0.88%, respectively. The fluxes of transfersome gel and control gel extract were 52.33±0.11 µg/cm²/hrs and 40.89±0.68 µg/cm²/hrs, respectively. Conclusions:Based on these results, it can be concluded that the gel with transfersome exhibited better penetration than the gel extract alone.

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In vitro photoprotective effects of Marcetia taxifolia ethanolic extract and its potential for sunscreen formulations

Cited by 45 publications

References 21 publications

In vitro evaluation of photoprotective potential of the different solvent extracts of Graptophyllum pictum leaves

In vitro evaluation of photoprotective potential of the different solvent extracts of Graptophyllum pictum leaves

In Vitro Assessment of Total Phenolic and Flavonoid Contents, Antioxidant and Photoprotective Activities of Crude Methanolic Extract of Aerial Parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria

Transfersome Gel Formulation of an Ethanol Extract of Apples (Malus Domestica Mill) Containing Antioxidants and in Vitro Penetration Testing Using Franz Diffusion Cells

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