“…NSAIDs-based local burn management currently relies upon the use of biodegradable and non-biodegradable biopolymers as potential carriers for controlled drug delivery systems (also called drug dressings) [ 23 ]. Such NSAIDs-based drug delivery systems (DDS) with non-biodegradable polymers support are to be avoided as they need frequent replacements that affect a patient’s comfort and can cause additional trauma to the new epithelial tissue formed, the risk of secondary infection being very high [ 7 , 9 , 24 , 25 , 26 , 27 ]. Therefore, biodegradable polymers are considered to be ideal vehicles for drugs delivery [ 28 ], collagen being preferred due to its properties such as biodegradability, bioresorbability, biocompatibility, hemostasis ability, well-known structure, and reduced manufacturing cost [ 29 , 30 , 31 , 32 , 33 , 34 , 35 ].…”