In vitro inhibitory effect of Streblus asper leaf-extract on adhesion of Candida albicans to human buccal epithelial cells

Taweechaisupapong, Suwimol; Choopan, T.; Singhara, S.; Chatrchaiwiwatana, Supaporn; Wongkham, Sopit

doi:10.1016/j.jep.2004.09.010

Cited by 41 publications

(26 citation statements)

References 44 publications

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“…The prevalence or trichomoniasis in this study was quite low at 2%, and it appears that there is a variation in the prevalence of this infection even in our environment with fi gures ranging from 2.8% to 18% [18,24,25]. However, the prevalence of trichomoniasis appears to be relatively lower than the other vaginal infections and seems to have declined when compared with earlier reports [26].…”

Section: Discussioncontrasting

confidence: 57%

Prevalence of vulvovaginal candidiasis, trichomoniasis and bacterial vaginosis among pregnant women receiving antenatal care in Southwestern Nigeria

Olowe¹,

Makanjuola²,

Olowe³

et al. 2014

European Journal of Microbiology and Immunology

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Vaginal infections in pregnancy are associated with considerable discomfort and adverse pregnancy outcomes including preterm delivery, low birth weight and increased infant mortality and also predisposition to HIV/AIDS. This study evaluated the prevalence and factors associated with vulvovaginal candidiasis, trichomoniasis and bacterial vaginosis among women attending antenatal clinic at a hospital in Nigeria. A semi-structured questionnaire was administered and high vaginal swab samples were obtained from consenting pregnant women. The samples were processed following standard protocols. The prevalence of vulvovaginal candidiasis was 36%, while those of trichomoniasis and bacterial vaginosis were 2% and 38%, respectively. Infections were higher in the third trimester and many women admitted to practices that increase risk of these infections. Significant association was found between recent intake of antibiotics and vaginal candidiasis, same association was also found with bacterial vaginosis. Adequate investigation and prompt treatment will reduce the morbidity and attendant effects of these prevalent infections on mother and fetus.

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Section: Discussioncontrasting

confidence: 57%

Prevalence of vulvovaginal candidiasis, trichomoniasis and bacterial vaginosis among pregnant women receiving antenatal care in Southwestern Nigeria

Olowe¹,

Makanjuola²,

Olowe³

et al. 2014

European Journal of Microbiology and Immunology

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“…Another study reported anti-candidal activity with leaf extract and exhibited potential controlling germ tube production by C. albicans adhesion. 30 The present study reports the moderate to least antifungal activity against Aspergillus spp. Fusarium spp.…”

Section: Resultsmentioning

confidence: 52%

Bioprospecting of some medicinal plants explored for antifungal activity

Kavitha¹,

Satish²

2015

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In the present study, evaluation of different plant parts of fifteen medicinal plants belonging to different families have been screened for in vitro efficacy of antifungal activity against phyto pathogenic (Aspergillus and Fusarium species) as well as human pathogenic fungi (Candida albicans and Microsporum species) using agar well diffusion assay. The results showed that among fifteen medicinal plants, crude extracts of different solvents viz., petroleum ether, chloroform, ethyl acetate and methanol tested for antifungal activity, twelve plants were found to be effective against one or the other test fungi, among these plants, solvent extracts of Callistemon lanceolatus showed significant activity against C. albicans, Microsporum gypseum, Cordia dichrotoma leaves extracts exhibited significant activity against A. niger, A. flavus and C. albicans. Sphaeranthus indicus L. whole plant extracts exhibited significant activity against Aspergillus spp., C. albicans and Microsporum canis. Leaves extracts of Vitex negundo exhibited significant activity against A. niger, A. flavus, F. verticillioides, C. albicans and moderate activity against F. crookwellense. Extracts of Butea monosperma exhibited significant to moderate activity against all test pathogens except C. albicans. The obtained results imparts a preliminary piece of significant information regarding the antifungal potentiality of screened medicinal plants with crude solvent extracts, which could be exploit for further isolation and investigation of antifungal agents for crop diseases management and human health.

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“…The other extracts and fractions of plants tested, amphotericin B and DMSO did not show a reduction in the viability of the murine macrophages. Taweechaisupapong et al (2005) demonstrated that Strebulus asper leaf extract interferes with in vitro adherence of C. albicans to BEC at a concentration of 1250 lg ml -1 . Polaquini et al (2006) reported an adhesion decrease in resin in two strains of C. albicans after contact with Neem (Azadirachta indica A. Juss) extract at a concentration of 1000 lg ml -1 .…”

Section: Resultsmentioning

confidence: 98%

Inhibitory effect of extracts from Brazilian medicinal plants on the adhesion of Candida albicans to buccal epithelial cells

Johann

Silva

Martins

et al. 2008

World J Microbiol Biotechnol

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Plants are known to produce a plethora of secondary metabolites which are recognized as a useful source of new drugs or drug leads. Extracts and fractions of Schinus terebinthifolius Raddi (Anacardiaceae), Piper regnellii C.D.C. (Piperaceae), Rumex acetosa L. (Polygonaceae), and Punica granatum L. (Punicaceae) were assessed for their antifungal activity against eight clinical isolates of C. albicans. They were also evaluated for their effect on the adhesion of these C. albicans isolates to buccal epithelial cells (BECs). The ethyl acetate fraction from the leaves of S. terebinthifolius showed promising activity, inhibiting the growth of three C. albicans isolates at 7.8 lg ml -1 and significantly inhibiting their adhesion to BEC at 15 lg ml -1 . In addition, this fraction did not show cytotoxic activity against murine macrophages. The results show the potential of the plant extracts studied as a source of new antifungal compounds. Further studies are necessary for isolation and characterization of the active compounds of these plants.

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In vitro inhibitory effect of Streblus asper leaf-extract on adhesion of Candida albicans to human buccal epithelial cells

Cited by 41 publications

References 44 publications

Prevalence of vulvovaginal candidiasis, trichomoniasis and bacterial vaginosis among pregnant women receiving antenatal care in Southwestern Nigeria

Prevalence of vulvovaginal candidiasis, trichomoniasis and bacterial vaginosis among pregnant women receiving antenatal care in Southwestern Nigeria

Bioprospecting of some medicinal plants explored for antifungal activity

Inhibitory effect of extracts from Brazilian medicinal plants on the adhesion of Candida albicans to buccal epithelial cells

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