2009
DOI: 10.1080/10496470903378854
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In Vitro HIV Type-1 Reverse Transcriptase Inhibitory Activity from Leaf Extracts ofScoparia dulcisL.

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Cited by 5 publications
(3 citation statements)
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“…This plant has been intensively studied as a traditional herbal medicine (Latha et al 2004). Previous studies have revealed that the presence of numerous phytochemicals, such as coumarins, saponins, tannins, flavonoids and various terpenoids like scoparic acid A, scoparic acid B, scopadulciol and scopadulin, in this plant species are responsible for its medicinal properties (Latha et al 2006(Latha et al , 2009Babincová et al 2008;Riel et al 2002;Porika et al 2009;Ahsan et al 2003). Some of these properties include antitumor-promoting activity, antihyperalgesic, antimalarial, antiulcer, antipyretic and aphrodisiac activities, as well as cytotoxicity activity against cancer cells (Taylor 2006).…”
Section: Introductionmentioning
confidence: 98%
“…This plant has been intensively studied as a traditional herbal medicine (Latha et al 2004). Previous studies have revealed that the presence of numerous phytochemicals, such as coumarins, saponins, tannins, flavonoids and various terpenoids like scoparic acid A, scoparic acid B, scopadulciol and scopadulin, in this plant species are responsible for its medicinal properties (Latha et al 2006(Latha et al , 2009Babincová et al 2008;Riel et al 2002;Porika et al 2009;Ahsan et al 2003). Some of these properties include antitumor-promoting activity, antihyperalgesic, antimalarial, antiulcer, antipyretic and aphrodisiac activities, as well as cytotoxicity activity against cancer cells (Taylor 2006).…”
Section: Introductionmentioning
confidence: 98%
“…Hispidulin, a steroidal glycoside isolated using an aqueous extract of S. dulcis exhibited anti HIV activity (Osei-Safo et al 2009). HIV type 1 reverse transcriptase inhibitory activity of methanolic extracts of leaf was also reported (Porika et al 2009).…”
Section: Introductionmentioning
confidence: 89%
“…Hydroxamic acid has been isolated from dried roots and aerial parts (Chiu-Ming and Ming-Tyan 1976), which exhibits insecticidal, antifungal and antibacterial activity. Moreover, our research group evaluated its efficacy towards reverse transcriptase (Porika et al 2009). In view of its wide ethnomedical acceptance it has attracted the attention of scientific community for its therapeutical values and thus remained as subject of intensified research.…”
Section: Introductionmentioning
confidence: 99%