In vitro Fluoride Uptake by Enamel from Different Amine Fluoride Concentrations

Abstract

The aim of this in vitro study was to examine whether the concentration of amine fluoride solution influences the uptake of fluoride by enamel after topical treatment. Four slabs were prepared from each of 31 impacted third molars and selected at random so that one slab from each tooth was present in each group. One group of slabs served as an untreated control (D). The slabs of the other three groups were shaken for 3 min in an amine fluoride solution on 3 successive days: group A (1% F), group B (0.5% F) and group C (0.25% F). The amounts of KOH-soluble fluoride produced with 1 and 0.5% amine fluoride solution did not differ significantly and were superior to 0.25% amine fluoride solution. A statistically significant increase in structurally bound fluoride was observed in groups A, B and C compared with control group D. The difference in the amounts of structurally bound fluoride was significant only between 1 and 0.25% F concentrations. These data suggest that the fluoride content in an amine fluoride solution (1%) can be decreased by half without reducing its ability to form alkali-soluble or structurally bound fluoride. The results of this study are consistent with those of previous clinical studies.

Influence of fluoride concentration and ethanol pre-treatment on the reduction of the acid susceptibility of enamel

“…39 As long as enough calcium ions are released from the enamel due to the low pH of the solutions, higher fluoride concentrations of the applied solutions consequently form more calcium fluoride. In contrast to the findings by Rosin-Grget et al 19 this evaluation revealed significant differences in the amount of formed KOH-soluble fluoride, increasing with the concentrations of the applied fluoride solutions (0.5, 1.0 and 1.5%). This can be explained by the pH-value of the solutions.…”

“…In the present study, the uptake of structurally bound fluoride showed a dose dependency with the concentration of the applied fluoride solutions, what is comparable with the findings of other studies 19,20 also there results were again not statistically significant. These minor differences could be again explained with the difference in the pH-values used in these studies.…”

“…This can be explained by the pH-value of the solutions. The pH-value of the solutions used in the present study was lower than the pH-values of the solutions used by Rosin-Grget et al 19 and so more calcium ions will be released from the enamel. Thus, more fluoride ions were able to form calcium fluoride like precipitates, resulting in an increase of calcium fluoride-like precipitate formation with increasing fluoride concentrations.…”

“…19,20 These studies were performed concerning the caries preventive effects of the calcium fluoride-like precipitate. The protective effect against erosions was not evaluated.…”

The Effect of Saliva on the Formation of KOH-Soluble Fluoride after Topical Application of Amine Fluoride Solutions of Varying Fluoride Concentration and pH

“…The present study was designed similarly to our previous in vitro studies [Rošin-Grget et al 2002, 2005 using similar concentrations and acidity of amine fluoride solution. The results show that saliva could increase the formation of KOH-soluble fluoride if the topical agents are not highly acidified.…”