In Vitro Evaluation of Phenolics Content, Antioxidant and Antimicrobial Activities of Three Centaurea L. Species from Iran

Bioactive Compounds of Verbascum sinuatum L.: Health Benefits and Potential as New Ingredients for Industrial Applications

“…However, in these two assays, the results were not comparable with those of the control. As in the previous study, the antioxidant activity was correlated with the high content of phenolic compounds (TPC = 118.2 mg GAE/g DW, TFC = 4.87 QE/g DW) [ 50 ]. More recently, a study evaluated the antioxidant activity of three fractions (n-Hexane, ethyl acetate, and water fractions) of the methanolic extract of V. sinuatum , among other plants of Verbascum genus [ 7 ].…”

“…Nowadays, much research has been done on different traditional medicinal plants to determine their real potential in the treatment of diseases caused by bacteria, viruses, and fungi, and to seek alternatives to synthetic antimicrobials and deal with the emergence of antimicrobial resistance. Further, the antioxidant assays conducted with different extracts have shown satisfactory results [ 7 , 22 , 23 , 50 , 51 ]. As it has been widely described, oxidative stress is involved in the development of cardiovascular diseases, cancer, obesity, diabetes, inflammatory diseases, aging, and degenerative diseases [ 89 , 90 ].…”

“…For example, the bioactive ingredients of this plant can be used as natural food preservatives to prolong the shelf life of food products through their antioxidant properties or used as functional ingredients or nutraceuticals, intended to produce functional foods. Many studies have reported the antioxidant properties of extracts of V. sinuatum [ 6 , 21 , 22 , 49 , 49 , 50 ], which could be considered for the development of preservative agents. This is in line with market trends, which seek a lower use of synthetic antioxidants such as butylated hydroxyl anisole (BHA), butylated hydroxytoluene (BHT), and tert-butylhydroquinone (TBHQ) as they have been related to adverse effects on the health of consumers.…”

Fullerene‐C60/NH2: A recyclable heterogeneous catalyst for the green synthesis of chromene and pyrimidine derivatives and antibacterial evaluation

“…Antibacterial activity study of some synthesized compounds (4g-i, 4o, and 7j) using disk diffusion method was investigated on S. aureus as Gram-positive and S. marcescens as Gram-negative microorganisms (Figure 7 and Table 5). First of all, it should be noted that a control using only DMSO showed no inhibition of the growth of tested bacteria under our experimental conditions [52][53][54]. The chromene 4g, 4o, and pyrimidine 7j compounds exhibited a good activity against S. aureus, while the chromene 4o and pyrimidine 7j compounds were not active against S. marcescens (Figure 7).…”

Isolation, characterization and anticancer activity of secondary metabolites from Verbascum speciosum

“…Verbascum species have been shown to possess different biological activities, such as antihelmintic (Kozan et al, 2011), anti‐carcinogen (Tatlı & Akdemir, 2004; Zhao et al, 2011), wound healing (Demirci et al, 2014; Kayır et al, 2018; Süntar et al, 2010), anti‐inflammatory (Akdemir et al, 2011; Speranza et al, 2010; Tatli et al, 2008), anxiolytic, preanestetic, sedative (Rezaie et al, 2012), antifungal and antioxidant (Karamian & Ghasemlou, 2013; Nofouzi, 2015; Saltan et al, 2011) effects were studied and possible mechanisms of action were defined. Especially well‐known species that are V. thapsus , V. phlomoides , V. lychnitis and V. nigrum are well‐studied due to their widespread use in traditional medicine (Robbers & Tyler, 1999).…”