In vitro evaluation of H2O2 hydrothermal treatment of aged titanium surface to enhance biofunctional activity

Abstract

Surface modification of titanium has been extensively investigated in implant science and technology in an effort to improve its osteoconductivity. The rate of protein adsorption on titanium surfaces is known to vary depending on the chemistry, structure, morphology, and titanium-specific biological aging of the surface. It is thus desirable to modify smooth titanium surfaces of miniimplants used as orthodontic anchors immediately prior to use. In this study, we have developed a simple surface modification of titanium alloy that improves its biofunctional activity. The surface of a Ti-6Al-4V disk was modified by applying 3% H 2 O 2 hydrothermal treatment using an autoclave. A nanostructured porous network TiO 2 was observed on the treated surface. Treated surfaces exhibited higher hydrophilicity, protein adsorption, and cell proliferation than untreated surfaces. 3% H 2 O 2 hydrothermal treatment is thought to provide biofunctional activity for aged titanium surface.

Three-dimensional finite element analysis of the stability of mini-implants close to the roots of adjacent teeth upon application of bite force

“…The implant surface treatment technology can increase the total surface area of the implant and enhance bone formation around the implant [12][13][14] . In recent years, surface modification techniques have been applied to the mini-implants to improve the initial stability 15) . Kim et al 16) observed the stability of a surface modified implant (1.8 mm in diameter) that was closer to the root and considered that the proximity of the implant to the tooth root only does not necessarily lead to mini-implant loss, and the underlying cause for implant loosening when close to the root remains unclear.…”

In Vitro and In Vivo Evaluation of Titanium Surface Modification for Biological Aging by Electrolytic Reducing Ionic Water

“…On the other hand, we have developed and reported an original technique in which aged Ti-6Al-4V disks were immersed in 3% H 2 O 2 and treated with hydrothermal oxidation at 121 • C /0.2 MPa for 20 min using an autoclave to form a new titanium oxide layer with an about 90 nm thickness, changing the titanium surface to hydrophilic [11]. Using this method, a hydrophilic titanium surface was acquired and protein adsorption and cell adhesion increased.…”

Manufacture of nanosized apatite coatings on titanium with different surface treatments using a supersaturated calcification solution

“…Acid etching and their combination with heat treatments (thermochemical treatments) are used for the surface modification of titanium, because they modify its elemental and phase composition, but also the topography and wettability. [29][30][31] In addition, this treatment improves the in vitro and in vivo behavior of titanium and its alloys. 9,29,32 Within the chemical procedures used to activate the surface of titanium and its alloys are treatments that enhance the formation of oxides or hydroxides, 30,31,33 and others which enable the formation of titanates (treatments in sodium hydroxide or calcium-ion solutions).…”

“…[29][30][31] In addition, this treatment improves the in vitro and in vivo behavior of titanium and its alloys. 9,29,32 Within the chemical procedures used to activate the surface of titanium and its alloys are treatments that enhance the formation of oxides or hydroxides, 30,31,33 and others which enable the formation of titanates (treatments in sodium hydroxide or calcium-ion solutions). 16,[34][35][36] The aim of this study is to determine the effect of four treatments of surface activation applied to the commercially pure titanium on the deposition of apatite coatings in a supersaturated calcification solution.…”