In vitro evaluation of bioactivity of SiO2-CaO-P2O5-Na2O-CaF2-ZnO glass-ceramics

Riaz, Madeeha; Zia, Rehana; Saleemi, Farhat; Bashir, Furrukh; Hossain, Tousif; Kayani, Zohra Nazir

doi:10.2478/s13536-014-0206-0

Cited by 10 publications

(1 citation statement)

References 21 publications

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“…The glass network connectivity of unsubstituted glass reduced upon the addition of CeO 2 , which mainly acts as a network modifier. Particularly, the oxygen buffering capacity of ceria is well recognized [23].Cerium oxide as redox-active rare earth ions grown wide interest in the biomedical field owing to its potential therapeutic applications in metabolic bone, cancer and infectious diseases.Whereas, ZnO doing as intermediate ions is a crucial trace element that stimulates bone formation [24,25]. Copper oxide (CuO) is an indispensable ion in the human body aimed at its significant role in the course of angiogenesis and the maturation of blood vessels.…”

Section: Resultsmentioning

confidence: 99%

Processing, Characterization and Application of Some Borophosphate Glasses Containing Antibacterial and Antifungal Oxides in Bioactive Demands

et al. 2018

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A SERIES of borophosphate glasses doped individually with few antimicrobial oxides; CeO 2 , ZnO and CuO were prepared by melt quenching technique. The structure and bioactivity of the prepared samples were analyzed through FTIR spectral technique and corrosion behavior before and after immersion for 2 weeks in simulated body fluid (SBF) under static condition. The microstructure of the glass was examined using SEM to confirm the bioactivity of glass through the formation of calcium phosphate (CaP) layer on the surface. FTIR spectra of the glass after immersion in SBF show characteristic peaks of calcium phosphate. Weight loss% display a difference in solubility in the SBF solution in relation to the antibacterial oxide added. SEM results show clear nodular microcrystalline calcium phosphate. The prepared glasses revealed effect against some microbes and bacteria. It was established that the addition of the antimicrobial oxides had a positive effect on the glass bioactivity and may find a part in the biomedical applications.

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Section: Resultsmentioning

confidence: 99%

Processing, Characterization and Application of Some Borophosphate Glasses Containing Antibacterial and Antifungal Oxides in Bioactive Demands

et al. 2018

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In vitro antimicrobial activity of ZnO based glass–ceramics against pathogenic bacteria

Riaz

Zia

Saleemi³

et al. 2015

J Mater Sci: Mater Med

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The antibacterial activity of ZnO (0-15.53 mol%) based SiO2-CaO-P2O5-Na2O-CaF2 bioactive glass-ceramics synthesized by controlled crystallisation were studied against eight micro-organisms using modified Kirby Bauer method. The antibacterial activity of the specimens was statistically evaluated using one-way analysis of variance and P < 0.05 was used as the level of significance. In vitro dissolution tests were performed in stimulated body fluid for 48 h at 37 °C for different time intervals to correlate the dissolution behaviour of test samples with antibacterial effects. The results illustrate that specimen BZn15.53 having the highest concentration of ZnO (15.53 mol%) demonstrated the strongest effect against Staph.aureus, S. epidermidis, B. subtilis and K. pneumonia. The effectiveness of BZn15.53 in inhibiting bacteria was due to accumulation of Zn(+2) ions around the surface of the bacteria cell release that caused the death of the cell, besides the presence of hydroxyapatite phase was also responsible for damaging the cell membrane of bacteria.

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Enhancing the properties of bone China ceramics by treatment with microporous SiO2 nanoparticles

Elmaaty¹,

Sayed-Ahmed

Gohari

et al. 2022

Chem. Pap.

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In this study, microporous silicon dioxide nanoparticles (SiO2–NPs) were used to improve the physical, chemical, and mechanical properties of bone China ceramics. Microporous SiO2–NPs were prepared economically from sodium metasilicate (SMS) as a precursor with cetyltrimethylammonium bromide (CTAB) as a surfactant at different concentrations. The prepared SiO2–NPs were characterized using scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and Raman spectroscopy to confirm the formation of microporous SiO2–NPs. The optimum concentrations of the precursor and surfactant used in the SiO2–NPs synthesis were set to be 1.5% and 2 g/200 ml, with a size range of 7–96 nm. SiO2–NPs prepared at the optimum concentrations were incorporated into bone China at different concentrations to evaluate their effect on flexural strength and elasticity. The bone China prepared using 1% SiO2–NPs (B1) had the highest flexural strength and Young's modulus values. Sample characteristics, including self-cleaning, differential scanning calorimetry, thermogravimetric analysis, bulk density (BD), apparent porosity (AP), and water absorption (WA), were investigated. The results revealed outstanding characteristic such as self-cleaning ability, remarkable increase in AP and WA, and a decrease in BD.

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In vitro evaluation of bioactivity of SiO2-CaO-P2O5-Na2O-CaF2-ZnO glass-ceramics

Cited by 10 publications

References 21 publications

Processing, Characterization and Application of Some Borophosphate Glasses Containing Antibacterial and Antifungal Oxides in Bioactive Demands

Processing, Characterization and Application of Some Borophosphate Glasses Containing Antibacterial and Antifungal Oxides in Bioactive Demands

In vitro antimicrobial activity of ZnO based glass–ceramics against pathogenic bacteria

Enhancing the properties of bone China ceramics by treatment with microporous SiO2 nanoparticles

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