In vitro efficacy of eugenol in inhibiting single and mixed-biofilms of drug-resistant strains of Candida albicans and Streptococcus mutans

Gomes

2019

JoF

The ability to form biofilms is a common feature of microorganisms, such as bacteria or fungi. These consortiums can colonize a variety of surfaces, such as host tissues, dentures, and catheters, resulting in infections highly resistant to drugs, when compared with their planktonic counterparts. This refractory effect is particularly critical in polymicrobial biofilms involving both fungi and bacteria. This review emphasizes Candida spp.-bacteria biofilms, the epidemiology of this community, the challenges in the eradication of such biofilms, and the most relevant treatments.

Section: Innovative Treatments Of Other Diseasesmentioning

confidence: 97%

Section: Innovative Treatments Of Other Diseasesmentioning

confidence: 99%

Candida spp./Bacteria Mixed Biofilms

Gomes

2019

JoF

“…A significant decrease in the expression of six virulence factor genes was also reported. A significant antibiofilm activity of eugenol against C. albicans and S. mutans was also observed in single and mixed biofilms [ 109 ]. Another study on the suppression effects of eugenol on biofilm- and quorum-sensing-related genes of S. mutans showed the significant effects of this compound at the sub-MIC [ 110 ].…”

Section: Main Constituents Of Cinnamomum Spp Amentioning

confidence: 99%

Effects of Cinnamon (Cinnamomum spp.) in Dentistry: A Review

Yanakiev

2020

Molecules

Dental medicine is one of the fields of medicine where the most common pathologies are of bacterial and fungal origins. This review is mainly focused on the antimicrobial effects of cinnamon essential oil (EO), cinnamon extracts, and pure compounds against different oral pathogens and the oral biofilm and the possible effects on soft mouth tissue. Basic information is provided about cinnamon, as is a review of its antimicrobial properties against the most common microorganisms causing dental caries, endodontic and periodontal lesions, and candidiasis. Cinnamon EO, cinnamon extracts, and pure compounds show significant antimicrobial activities against oral pathogens and could be beneficial in caries and periodontal disease prevention, endodontics, and candidiasis treatment.

Essential Oils - Oils of Nature

“…Also in this case, such capability cannot be expanded to every strain of C. albicans neither to all strains of S. mutans. In fact, Jafri and co-workers [98] ascertained that eugenol is effective against the biofilm formed by two of more than ten strains of C. albicans (in particular, the strain CAJ-01) and S. mutans (strain MTCC497), studied singularly on in mixed form, with a concurrent reduction of cell viability and a disruption of cell membrane.…”

Section: Action Of Eos On Biofilm Of Eukaryotesmentioning

confidence: 99%

Essential Oils and Microbial Communication

Nazzaro¹,

Fratianni²,

d’Acierno³

et al. 2020

The World Health Organization highlighted the increase in the resistance to conventional antibiotics for most pathogens and observed also a decrease of the threshold for all mechanisms of cell-cell microbial communication, leading to the formation of biofilms and to the increase of microbial pathogenicity. Scientific community is therefore oriented to the identification and study of alternative substances to antibiotics. In such context, substances of vegetal source, such as essential oils (EOs), always used in traditional medicine, stimulated-particularly in recent decades-the scientific world to discover and identify substances, intended as a mixture or single components capable to fight pathogenic microorganisms. From this point of view, the study of plants is very interesting and offers many interesting ideas and results. This brief chapter describes the basis of the microbial communication, until the formation of biofilm, and some mechanisms through which essential oils, or some of their main components, may decrease or inactivate the complex mechanisms that lead to pathogenicity, both of prokaryotes and eukaryotes.