In vitro effect of phospholipase C from bacillus cereus on tissue thromboplastin from different species

The secretion of clotting factors by rat spleen macrophages and human peripheral blood monocytes has been studied. The results show that the amount of clotting factors measured depends critically upon the characteristics of the assay system used. The presence of warfarin, salicylic acid or thrombin in the culture medium is shown to decrease the vitamin K dependent clotting factor activity in the supernatant after in vitro culture of rat spleen macrophages and human peripheral blood monocytes.

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Clotting factors secreted by monocytes and macrophages: Analytical considerations

Dam-Mieras¹,

Muller²,

Deijk³

et al. 1985

Thrombosis Research

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A simple method for determination of the factor VII-phospholipid complex using normotest

Dalaker

Janson

Johnsen

et al. 1987

Thrombosis Research

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A comparative study of conventional versus new, magnesium-poor Vacutainer® Sodium Citrate blood collection tubes for determination of prothrombin time and INR

Besselaar

Vlodrop

Berendes

et al. 2014

Thrombosis Research

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In vitro effect of phospholipase C from bacillus cereus on tissue thromboplastin from different species

Cited by 6 publications

References 16 publications

Clotting factors secreted by monocytes and macrophages: Analytical considerations

Clotting factors secreted by monocytes and macrophages: Analytical considerations

A simple method for determination of the factor VII-phospholipid complex using normotest

A comparative study of conventional versus new, magnesium-poor Vacutainer® Sodium Citrate blood collection tubes for determination of prothrombin time and INR

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