In vitro degradation and biomineralization ability of hydroxyapatite coated Mg-9Li-7Al-1Sn and Mg-9Li-5Al-3Sn-1Zn alloys

Maurya, Rita; Siddiqui, Abdul Rahim; Balani, Kantesh

doi:10.1016/j.surfcoat.2017.06.027

Cited by 24 publications

(11 citation statements)

References 53 publications

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“…Table 3 , n 1 for coating, n 2 for double layer), j is an imaginary unit, and ω is the angular frequency. To obtain an improved quality of fit, it is frequently applied to replace the capacitor ( Jayaraj et al, 2016 ; Maurya et al, 2017 ). R ads and L ads represent the inductive loop at low frequencies and are normally related to the exposure of the Mg substrate and the release of Mg 2+ and Mg(OH) 2 ( Cui et al, 2019 ).…”

Section: Resultsmentioning

confidence: 99%

“…Moreover, the Ca and P content on the surface of all coated samples and the Ca/P atomic ratio of samples treated at pH 5.5 and 8.5 increase after the electrochemical test (ref. Figure 4 ) probably because when the nacre coating is immersed in SBF, the ion exchange controls its dissolution, and electrostatic interactions between negatively charged groups on the surface and ions in SBF trigger further biomineralization ( Maurya et al, 2017 ).…”

Section: Resultsmentioning

confidence: 99%

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Corrosion Behavior and Biocompatibility of Na2EDTA-Induced Nacre Coatings on AZ91D Alloys Prepared via Hydrothermal Treatment

et al. 2022

Front. Chem.

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An effective method for controlling the corrosion rate of Mg-based implants must be urgently developed to meet the requirements of clinical applications. As a naturally occurring osteoid material, nacre offers a strategy to endow biomedical Mg alloys with excellent biocompatibility, and corrosion resistance. In this study, pearl powder and NaH2PO4 were used as precursors to deposit coatings on AZ91D alloy substrates hydrothermally based on Na2EDTA-assisted induction. Na2EDTA-induced nacre coatings were fabricated at various pH values, and its chemical composition and microstructure were analyzed via energy-dispersive X-ray, scanning electron microscopy, and X-ray diffraction spectroscopy. The corrosion-resistant performance and cytocompatibility of the samples were evaluated via electrochemical measurements and in vitro cell experiments. Results showed that the samples hydrothermally treated under faint acid conditions present excellent corrosion resistance, whereas the samples treated under slight alkaline conditions demonstrate improved biocompatibility due to high Ca and P content and large Ca/P atomic ratio. This study provides substantial evidence of the potential value of nacre coatings in expanding the biological applications of implanted biomaterials.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Corrosion Behavior and Biocompatibility of Na2EDTA-Induced Nacre Coatings on AZ91D Alloys Prepared via Hydrothermal Treatment

et al. 2022

Front. Chem.

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“…Previous studies reported that the degradation rate of PDLLA under alkaline conditions was higher than that under acidic conditions. (Maurya et al, 2017, Rodenas-Rochina et al, 2015. Therefore, the results showed that the PDLLA and 10% HA/PDLLA composite had higher degradation rates and the weight loss rate of 10% HA/PDLLA composite was faster.…”

Section: Biological Properties Of Selective Laser Sintering Samplesmentioning

confidence: 91%

Selective laser sintered nano-HA/PDLLA composite microspheres for bone scaffolds applications

Lin

Liu

et al. 2020

RPJ

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Purpose The main cause of aseptic inflammation after an in vivo implantation is that Poly(L-lactide) (PLLA) and Poly(D-lactide) have a slower degradation and absorption rate, while Poly(D, L-lactide) (PDLLA) has a much faster degradation rate than PLLA because of its amorphous structure. Also, the hydrolyzate of Hydroxyapatite (HA) is alkaline, which can neutralize local tissue peracid caused by hydrolysis of Polylactic acid. Design/methodology/approach In this study, the selective laser sintering (SLS) technique was chosen to prepare bone scaffolds using nano-HA/PDLLA composite microspheres, which were prepared by the solid-in-oil-in-water (S/O/W) method. First, the SLS parameters range of bulk was determined by the result of a single-layer experiment and the optimized parameters were then obtained by the orthogonal experiment. The tensile property, hydrophobicity, biocompatibility, biological toxicity and in vitro degradation of the samples with optimized SLS parameters were characterized. Findings As a result, the samples showed a lower tensile strength because of the many holes in their interior, which was conducive to better cell adhesion and nutrient transport. In addition, the samples retained their inherent properties after SLS and the hydrophobicity was improved after adding nano-HA because of the OH group. Furthermore, the samples showed good biocompatibility with the large number of cells adhering to the material through pseudopods and there was no significant difference between the pure PDLLA and 10% HA/PDLLA in terms of biological toxicity. Finally, the degradation rate of the composites could be tailored by the amount of nano-HA. Originality/value This study combined the S/O/W and SLS technique and provides a theoretical future basis for the preparation of drug-loaded microsphere scaffolds through SLS using HA/PDLLA composites.

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“…Numerous materials and techniques have been tested for this purpose (Kannan, Walter, Yamamoto, Khakbaz, & Blawert, 2018;Müller et al, 2005;Surmeneva, Mukhametkaliyev, Khakbaz, Surmenev, & Bobby Kannan, 2015); however, calcium phosphate (CaP) coating has been very popular for a number of reasons, including bone composition being ~69 wt% of CaP and it is relatively easy to deposit CaP on metals. The biocompatibility and osteoconductivity of CaP and its tendency to accelerate bone growth are well documented in the literature (Maurya, Siddiqui, & Balani, 2017;Paital & Dahotre, 2009).…”

Section: Introductionmentioning

confidence: 99%

Biodegradable 3D porous zinc alloy scaffold for bone fracture fixation devices

et al. 2020

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et al., 2016) metal that has potential implant applications such as bone fracture fixation devices. Being an essential nutrient for human body, zinc is required for many different biological functions such as wound healing (Andrews & Gallagher-Allred, 1999), cell proliferation and DNA stabilization (MacDonald, 2000; Wu & Wu, 1987). Furthermore, zinc possesses anti-inflammatory effects and is haemocompatible and used by the human body as a hormone mediator (Beyersmann & Haase, 2001; Tapiero & Tew, 2003). Although the daily recommended dietary allowance (RDA) for zinc is limited to 8-11 mg/day, zinc overdose (10 times the RDA) has shown no adverse effects in humans (Samman & Roberts, 1987). In fact, a study has shown that high concentrations of zinc prevent conditions like osteoporosis (Luo et al., 2014). The physical and mechanical properties of metallic zinc (density = 7.14 g/cm 3 ; young's modulus = 70 GPa, and ultimate tensile strength (UTS) = 126-246 MPa; Porter, 1991) are similar to those of other metallic implant materials. For orthopaedic temporary implants for bone fracture fixation (e.g. bone plates), the implant material should possess excellent load-bearing capacity during service.

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In vitro degradation and biomineralization ability of hydroxyapatite coated Mg-9Li-7Al-1Sn and Mg-9Li-5Al-3Sn-1Zn alloys

Cited by 24 publications

References 53 publications

Corrosion Behavior and Biocompatibility of Na2EDTA-Induced Nacre Coatings on AZ91D Alloys Prepared via Hydrothermal Treatment

Corrosion Behavior and Biocompatibility of Na2EDTA-Induced Nacre Coatings on AZ91D Alloys Prepared via Hydrothermal Treatment

Selective laser sintered nano-HA/PDLLA composite microspheres for bone scaffolds applications

Biodegradable 3D porous zinc alloy scaffold for bone fracture fixation devices

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