In vitro cytotoxicity against human cancer cell lines (MCF-7 and AGS), antileishmanial and antibacterial activities of green synthesized silver nanoparticles using Scrophularia striata extract

Ebrahimzadeh, Mohammad Ali; Hashemi, Zahra; Mohammadyan, Mahsa; Fakhar, Mahdi; Mortazavi‐Derazkola, Sobhan

doi:10.1016/j.surfin.2021.100963

Cited by 45 publications

(14 citation statements)

References 30 publications

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“…The results of this study are comparable with previous studies on green-synthesized nanosilver with different plants in anti-cancer effect with AGS cell line. 84–86 The results also suggest a potential anticancer effect of P. trimera against gastric cancer cell lines. This result is similar to previous reports on the anti-cancer effect of P. trimera on the cell lines MCF-7, HT29, H460….…”

Section: Resultsmentioning

confidence: 81%

Green, facile and fast synthesis of silver nanoparticles by using solution plasma techniques and their antibacterial and anticancer activities

et al. 2023

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Section: Resultsmentioning

confidence: 81%

Green, facile and fast synthesis of silver nanoparticles by using solution plasma techniques and their antibacterial and anticancer activities

et al. 2023

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“…Figure 8 showed that the maximum zone of inhibition was found to be 29.3±0.9, 48.48±0.7 and 54.52±1.1 when used FeGANF‐20 in the presence of 20 % H 2 O 2 against E. coli , S. aureus and C. albicans , respectively. The mechanism of antimicrobial activity of nanomaterials have not been fully explained [39] . But our proposed mechanism of antimicrobial activity can be reported as rapid denaturation of cells via ⋅OH induced membrane damage [40,41] …”

Section: Resultsmentioning

confidence: 96%

“…The mechanism of antimicrobial activity of nanomaterials have not been fully explained. [39] But our proposed mechanism of antimicrobial activity can be reported as rapid denaturation of cells via * OH induced membrane damage. [40,41]…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Natural Molecule‐Incorporated Magnetic Organic‐Inorganic Nanoflower: Investigation of Its Dual Fenton Reaction‐Dependent Enzyme‐Like Catalytic Activities with Cyclic Use

et al. 2023

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The functional organic‐inorganic hybrid nanoflowers (hNFs) have recently attracted considerable attention due to enhanced catalytic activity and stability. The main purpose of this study is to synthesize new Fenton reagents and investigate their catalytic activity, dye degradation performance and antimicrobial activity. This magnetic gallic acid nanoflowers (FeGANF) were self‐assembled via incorporating magnetic nanoparticles (Fe3O4 NPs) into gallic acid (GA) as organic part and copper(II) phosphate (Cu3(PO4)2) as inorganic parts. The FeGANF were characterized by SEM, EDX, FT‐IR and XRD. The peroxidase‐like activity and dye degradation performance of FeGANF and GANF based on Fenton reaction in the presence of H2O2 was studied toward guaiacol as substrate, using methylene blue (MB) and congo red (CR) as a cationic and anionic dyes, respectively. FeGANF shows much high catalytic activity and decoloration efficiency (97 % for MB and 99 % for CR) because of dual active center in Fenton reaction on the surface of FeGANF. FeGANF exhibited more antimicrobial activity against Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923, and Candida albicans ATCC 10231 than that of the GA and GANF. The results of these studies suggest that magnetic hNFs has proved to be promising Fenton reagents for biological and environmental applications including treatment of wastewater.

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“…Consequently, drugs, cosmetics, and animal food supplements are just a few of the applications for ZnO-NPs [15]. Besides zinc, silver (Ag) and gold have been observed for their killing activities against bacteria, viruses, fungi, microbes, and cancer [16][17][18][19][20]. As a result, research into silver and gold nanoparticles and their positive effects on medicine and human health has become a potential concern.…”

Section: Introductionmentioning

confidence: 99%

The Promising Antibacterial and Anticancer Activity of Green Synthesized Zinc Nanoparticles in Combination with Silver and Gold Nanoparticles

Abdelsattar

Kamel

Hussein

et al. 2023

J Inorg Organomet Polym

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Zinc nanoparticles (ZnNPs) are showing promising medical applications. However, their cytotoxicity is relatively high. This study aims to use a green synthesis technique based on the natural propolis (honeybees glue) and produce three counterparts of Zinc nanoparticles (ZnO-NPs, AuNPs@ZnO and AgNPs@ZnO). Then, the three would be analyzed for their potential antibacterial activity and cytotoxicity. The study compares the antibacterial activity and cytotoxicity of ZnO-NPs alone to its combination with gold and silver (AuNPs@ZnO and AgNPs@ZnO). The results showed that AgNPs@ZnO had contributed significantly to antibacterial activity against Gram-positive and Gram-negative bacteria. Moreover, AuNPs@ZnO and AgNPs@ZnO showed similar cytotoxicity to ZnO-NPs with higher safety. Furthermore, the Scanning and Transmission Electron Microscopes’ micrographs (SEM and TEM) displayed the biosynthesized ZnNPs that have a spherical shape with sizes ranging from 17 to 70 nm, from 45 to 75 nm, and from 22 to 73 nm for ZnONPs, ZnO-AgNPs, free AgNPs, and ZnO-AuNPs, respectively. In addition, zeta potential values for ZnONPs were 11.4 mV, while ZnO-AgNPs and ZnO-AuNPs have a higher overall charge of 13.6 mV and 23.9 mV, respectively. Furthermore, ZnNPs exhibited antibacterial activity, yet AgNPs@ZnO demonstrated the highest antibacterial action against Gram-negative and Gram-positive bacteria. In addition, cytotoxicity analyses of biosynthesized ZnNPs on three cell lines; breast cancer cell (MCF-7), liver cancer cell (HepG-2) and Human skin fibroblast (HSF) revealed that Zn-NPs in a combination could function as an anticancer agent. Therefore, there are promising medical applications for the biosynthesized ZnNPs in combinations with other metals, such as ZnO-AgNPs, as safe antibacterial and anticancer medicines. Graphical Abstract

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In vitro cytotoxicity against human cancer cell lines (MCF-7 and AGS), antileishmanial and antibacterial activities of green synthesized silver nanoparticles using Scrophularia striata extract

Cited by 45 publications

References 30 publications

Green, facile and fast synthesis of silver nanoparticles by using solution plasma techniques and their antibacterial and anticancer activities

Green, facile and fast synthesis of silver nanoparticles by using solution plasma techniques and their antibacterial and anticancer activities

Natural Molecule‐Incorporated Magnetic Organic‐Inorganic Nanoflower: Investigation of Its Dual Fenton Reaction‐Dependent Enzyme‐Like Catalytic Activities with Cyclic Use

The Promising Antibacterial and Anticancer Activity of Green Synthesized Zinc Nanoparticles in Combination with Silver and Gold Nanoparticles

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