Abstract:The in vitro study of the interactions between S. mutans and S. sobrinus is important to determine the role of these microorganisms in the formation of biofilms on dental structures and their potential to induce carious lesions. The objective of this research was to study the suppression of bacterial plaque formation and its recolonization by rifampycin-resistant S.mutans and streptomycin-resistant S. sobrinus. To study the competitive relationship between these species, previously standardized strains were in… Show more
“…The association between the species S. mutans and S. sobrinus appears to favor an increase in caries index of individuals. The occurrence of the species S. mutans in 69.0% of the individuals in this study can be related to their capacity to inhibit the formation of bacterial biofilm by other species and recolonize the tooth surface as shown in a study by Pereira et al [27]. The results obtained in the present study regarding the identification of S. mutans and S. sobrinus coincided with those of cited studies and show that these species had a high prevalence in the specimens isolated as well as in the individuals studied.…”
This study investigated the association between clinical and salivary or molecular parameters in Down syndrome subjects. Sixty individuals (1- to 48-year old) were clinically examined using DMFT/DMFS. Stimulated saliva was collected; salivary flow was calculated (mL/min), buffering capacity was measured using a standard pH tape. In addition, 25 μL of saliva was diluted using 10-fold-dilution method and then placed on Mitis-Salivarius-Bacitracin agar to count colony forming units (CFU/mL) of mutans streptococci. Polymerase chain reaction analysis identified species. Caries indexes were 0.65-13.5 (DMFT) and 0.65-26.0 (DMFS) according to groups. Ninety-four percent of subjects had low flow rate (0.7-1.0 mL/min) and 44% had low buffering capacity (pH < 4). Besides, 60% had more than 1 × 10(6) CFU/mL, 60% had S. mutans, and 41.4% had S. sobrinus. Caries indexes did not significantly correlate with flow rate, buffering capacity, CFU/mL by Pearson's correlation (p > 0.05), and showed no significant association with prevalence of species by Chi-square (p > 0.05). There is no association between clinical picture and salivary or molecular parameters in Down syndrome subjects.
“…The association between the species S. mutans and S. sobrinus appears to favor an increase in caries index of individuals. The occurrence of the species S. mutans in 69.0% of the individuals in this study can be related to their capacity to inhibit the formation of bacterial biofilm by other species and recolonize the tooth surface as shown in a study by Pereira et al [27]. The results obtained in the present study regarding the identification of S. mutans and S. sobrinus coincided with those of cited studies and show that these species had a high prevalence in the specimens isolated as well as in the individuals studied.…”
This study investigated the association between clinical and salivary or molecular parameters in Down syndrome subjects. Sixty individuals (1- to 48-year old) were clinically examined using DMFT/DMFS. Stimulated saliva was collected; salivary flow was calculated (mL/min), buffering capacity was measured using a standard pH tape. In addition, 25 μL of saliva was diluted using 10-fold-dilution method and then placed on Mitis-Salivarius-Bacitracin agar to count colony forming units (CFU/mL) of mutans streptococci. Polymerase chain reaction analysis identified species. Caries indexes were 0.65-13.5 (DMFT) and 0.65-26.0 (DMFS) according to groups. Ninety-four percent of subjects had low flow rate (0.7-1.0 mL/min) and 44% had low buffering capacity (pH < 4). Besides, 60% had more than 1 × 10(6) CFU/mL, 60% had S. mutans, and 41.4% had S. sobrinus. Caries indexes did not significantly correlate with flow rate, buffering capacity, CFU/mL by Pearson's correlation (p > 0.05), and showed no significant association with prevalence of species by Chi-square (p > 0.05). There is no association between clinical picture and salivary or molecular parameters in Down syndrome subjects.
“…Moreover, S. mutans colocalized with S. sobrinus in the biofilm ( Fig. 4 A), which indicated that the two species might have a symbiotic relationship and accelerate the progression of caries when combined [ 42 , 43 ]. Fig.…”
“…Streptococcus mutans is closely associated with dental caries, mainly those involving smooth surfaces [2]. The primary habitats for S. mutans are mouth, pharynx and intestine.…”
This work was carried out in collaboration between all authors. Author PSJ designed the study, performed the statistical analysis, wrote the protocol, and wrote the first draft of the manuscript and managed literature searches. Authors MC, SGJR, BPH and RSK managed the analyses of the study and literature searches. All authors read and approved the final manuscript.
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