In-vitro assessment of HA-Nb coating on Mg alloy ZK60 for biomedical applications

Singh, Balwinder; Singh, Gurpreet; Sidhu, Buta Singh; Bhatia, Nitish

doi:10.1016/j.matchemphys.2019.04.037

Cited by 46 publications

(14 citation statements)

References 78 publications

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“…The mechanism of pore formation during the potentiodynamic polarization technique with Hanks' solution follows two processes: (i) the formation of H+ ions on the implant surface, and (ii) the acidification of the medium by producing H+ ions that dissolve the HAp and form larger pores [64]. Hence, to resolve these issues, researchers around the world have recently been attempting to amalgamate reinforcement agents such as CNT, Nb, Ag, Sr, Fe 3 O 4 , Si, Mg, and so on with HAp to prevent this manner of dissolution, which significantly improves the mechanical properties, including the microhardness, wear resistance, and corrosion resistance [39,174,175,[177][178][179].…”

Section: Importance Of Hap-based Coatings For the Corrosion Behavior Of Biomaterialsmentioning

confidence: 99%

“…The modified surface responses, such as the coating properties, microhardness, and resistance to wear and corrosion, significantly influence the biocompatibility, biofunctions, and durability of the biomaterials [38][39][40]. Hydroxyapatite (HA) is considered a bio-ceramic powder that is used to form a biocompatible coating on the machined biomaterial surface to enhance the biological response because it serves Ca, P, and O [9,11].…”

Section: Introductionmentioning

confidence: 99%

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Investigation of Coatings, Corrosion and Wear Characteristics of Machined Biomaterials through Hydroxyapatite Mixed-EDM Process: A Review

et al. 2021

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Together, 316L steel, magnesium-alloy, Ni-Ti, titanium-alloy, and cobalt-alloy are commonly employed biomaterials for biomedical applications due to their excellent mechanical characteristics and resistance to corrosion, even though at times they can be incompatible with the body. This is attributed to their poor biofunction, whereby they tend to release contaminants from their attenuated surfaces. Coating of the surface is therefore required to mitigate the release of contaminants. The coating of biomaterials can be achieved through either physical or chemical deposition techniques. However, a newly developed manufacturing process, known as powder mixed-electro discharge machining (PM-EDM), is enabling these biomaterials to be concurrently machined and coated. Thermoelectrical processes allow the migration and removal of the materials from the machined surface caused by melting and chemical reactions during the machining. Hydroxyapatite powder (HAp), yielding Ca, P, and O, is widely used to form biocompatible coatings. The HAp added-EDM process has been reported to significantly improve the coating properties, corrosion, and wear resistance, and biofunctions of biomaterials. This article extensively explores the current development of bio-coatings and the wear and corrosion characteristics of biomaterials through the HAp mixed-EDM process, including the importance of these for biomaterial performance. This review presents a comparative analysis of machined surface properties using the existing deposition methods and the EDM technique employing HAp. The dominance of the process factors over the performance is discussed thoroughly. This study also discusses challenges and areas for future research.

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Section: Importance Of Hap-based Coatings For the Corrosion Behavior Of Biomaterialsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Investigation of Coatings, Corrosion and Wear Characteristics of Machined Biomaterials through Hydroxyapatite Mixed-EDM Process: A Review

et al. 2021

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“…With a progressive increment in the Nb content in HA, the protection efficiency (Pe) for HA–Nb coatings was increased (~4, 12, and 18%), in comparison to the pure HA coating. The HA–Nb coatings exhibited no adverse effect on the erythrocytes, and the hemolysis rate (HR) was within the domain of safe values (<5%) for implant materials [ 21 ]. However, there are still problems for plasma spraying, for example, due to the high temperature of spraying, the HA coating would produce an amorphous phase after spraying, which might affect the interface integrity of the bone implant.…”

Section: Preparation and Properties Of Ha Coatingmentioning

confidence: 99%

Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review

et al. 2021

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The wide application of magnesium alloys as biodegradable implant materials is limited because of their fast degradation rate. Hydroxyapatite (HA) coating can reduce the degradation rate of Mg alloys and improve the biological activity of Mg alloys, and has the ability of bone induction and bone conduction. The preparation of HA coating on the surface of degradable Mg alloys can improve the existing problems, to a certain extent. This paper reviewed different preparation methods of HA coatings on biodegradable Mg alloys, and their effects on magnesium alloys’ degradation, biocompatibility, and osteogenic properties. However, no coating prepared can meet the above requirements. There was a lack of systematic research on the degradation of coating samples in vivo, and the osteogenic performance. Therefore, future research can focus on combining existing coating preparation technology and complementary advantages to develop new coating preparation techniques, to obtain more balanced coatings. Second, further study on the metabolic mechanism of HA-coated Mg alloys in vivo can help to predict its degradation behavior, and finally achieve controllable degradation, and further promote the study of the osteogenic effect of HA-coated Mg alloys in vivo.

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“…NaOH and ZnSO 4 as accelerators were added to phosphatizing baths, with an aim to form a dense and uniform protective phosphate coating. It Types of protective coatings used to delay/reduce the degradation rate of magnesium alloys [68][69][70][71][72][73][74][75][76][77].…”

Section: Methods Of Reducing the Degradation Rate Of Magnesium Alloysmentioning

confidence: 99%

Amorphous and Crystalline Magnesium Alloys for Biomedical Applications

Cesarz-Andraczke¹,

Kania²,

Młynarek³

et al. 2022

Magnesium Alloys Structure and Properties

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Amorphous and crystalline magnesium alloys, developed for medical applications – especially implantology – present the characteristics of biocompatible magnesium alloys (Mg-Zn, Mg-Zn-Ca, Mg-Ca etc.). This chapter provides a brief description of the role of magnesium in the human body and the use of Mg in medicine. It presents the concept of using magnesium alloys in medicine (advantages and limitations) and the scope of their potential applications (orthopedic implantology, cardiac surgery etc.). The chapter shows classification of magnesium alloys as potential biomaterials, due to their structure (amorphous, crystalline) and alloying elements (rare earth elements, noble metals etc.). The mechanism and in vitro degradation behavior of magnesium alloys with amorphous and crystalline structures are described. The chapter also discusses the influence of alloying elements (rare earth elements, noble metals) on the in vitro degradation process. It also presents the methods of reducing the degradation rate of magnesium alloys by modifying their surface (application of protective layers).

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In-vitro assessment of HA-Nb coating on Mg alloy ZK60 for biomedical applications

Cited by 46 publications

References 78 publications

Investigation of Coatings, Corrosion and Wear Characteristics of Machined Biomaterials through Hydroxyapatite Mixed-EDM Process: A Review

Investigation of Coatings, Corrosion and Wear Characteristics of Machined Biomaterials through Hydroxyapatite Mixed-EDM Process: A Review

Recent Advances on Development of Hydroxyapatite Coating on Biodegradable Magnesium Alloys: A Review

Amorphous and Crystalline Magnesium Alloys for Biomedical Applications

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