In Vitro Antioxidant, Anti-Inflammatory And Anti-Microbial Activity of Carica Papaya Seeds

Singh, Pooja G; B, Madhu S.; Shailasreesekhar, Shailasreesekhar; Ts, Gopenath; Basalingappa, Kanthesh M.; Bv, Sushma

doi:10.34257/gjmrbvol20is2pg19

Cited by 9 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We found that the concentration-dependent activity of AgNPs was 56% for synthesised AgNPs and 38% for commercially available CPPE [ 39 ]. According to a recent study, the antioxidant activity of methanolic extract of papaya leaf was assessed by measuring its ability to neutralise free radicals (DPPH) [ 40 ]. DPPH free radical scavenging capacity was found to be best in hexane extract and lowest in aqueous extract in another investigation using papaya seed extracts and the results showed [ 41 ].…”

Section: Bioactivities Of Papaya Leaf Extractmentioning

confidence: 99%

Carica papaya L. Leaves: Deciphering Its Antioxidant Bioactives, Biological Activities, Innovative Products, and Safety Aspects

Sharma

et al. 2022

Oxidative Medicine and Cellular Longevity

View full text Add to dashboard Cite

The prevalence of viral infections, cancer, and diabetes is increasing at an alarming rate around the world, and these diseases are now considered to be the most serious risks to human well-being in the modern period. There is a widespread practice in Asian countries of using papaya leaves (C. papaya L.) as herbal medicine, either alone or in combination with prescribed medications, to treat a variety of ailments. The importance of conducting the necessary descriptive studies in order to determine the safety of papaya leaf consumption is also emphasized in the context of their application in the healthcare sector. Electronic databases such as Google Scholar, Scopus, and PubMed were used to gather information on papaya leaves, their therapeutic potential, and clinical evidence-based studies. The literature was gathered from publications on papaya leaves, their therapeutic potential, and clinical evidence-based studies. The antidengue, anticancer, antidiabetic, neuroprotective, and anti-inflammatory effects of papaya leaves discussed in this article are supported by evidence from preclinical, in vivo, in vitro, and clinical trial studies, as well as from other sources. Leaves have been investigated for their mechanism of action as well as their potential to be used in the development of novel herbal products for the health business. According to the reports gathered, only a small number of research demonstrated that leaf extract at high concentrations was hazardous to certain organs. The collective literature reviewed in this review provides insights into the use of papaya leaves as a cure for epidemic diseases, highlighting the phytochemical composition and pharmacological attributes of papaya leaves, as well as the results of various preclinical and clinical studies that have been conducted so far on the subject. The review clearly demonstrates the successful medical evidence for the use of papaya leaf extracts in the healthcare system as a supplemental herbal medication in a variety of clinical settings.

show abstract

Section: Bioactivities Of Papaya Leaf Extractmentioning

confidence: 99%

Carica papaya L. Leaves: Deciphering Its Antioxidant Bioactives, Biological Activities, Innovative Products, and Safety Aspects

Sharma

et al. 2022

Oxidative Medicine and Cellular Longevity

View full text Add to dashboard Cite

show abstract

“…According to Singh et al [9], the antioxidant activity of Carica family plants comes from the secondary metabolite content in the form of salicylic acid, p−hydroxybenzoic acid, phenolic compounds in the form of hyperosids, antioxidant compounds of gentisyl alcohol, gallotannin ester compounds, and kaemferol hexoside which is a flavonol glucoside.…”

Section: Antioxidant Capacitymentioning

confidence: 99%

Effect of Roasting Process on Antioxidant Activity of Carica Seeds Coffee (Carica pubescens)

Sukowati¹,

Arif²,

Heryanto³

2022

Indones. J. Chem. Stud.

View full text Add to dashboard Cite

Carica seeds (Carica pubescens), one of the diversification of coffee drinks, served as antioxidants. The roasting process generated degradation of secondary metabolic compounds but produced Maillard reactions products (MRPs). The study aimed to determine the effect of the roasting process on the antioxidant activity of Carica coffee beans and its correlation to the Maillard reaction. The samples roasting temperatures were 100–115, 150–165, and 200–215 °C. The samples were analyzed for proximate, total phenolic, antioxidant, and FTIR. The moisture and ash content of dry seeds were according to SNI 01-2907-2008. The total phenolic content was 3.21–8.99 µgGAE/g, with the highest contents at 200–215 °C. The antioxidant activity was 83–459.67 ppm AEAC. The high phenolic content and antioxidant at 200–215 °C were thought to come from MRPs compounds. The FTIR spectra showed stretching of OH, C=C (aromatic), C=N, C=O, and C-OH (phenol). The spectrum intensity weakened at higher temperatures. However, only the nC–H stretching at 200–215 °C became stronger. The Cluster Ward analysis showed resemblance spectra at roasting temperature levels of 100–115 and 150–165 °C. The roasting process affected the antioxidant activity of Carica coffee beans, thereby increasing the roasting temperature level. This condition resulted in higher levels of antioxidants.

show abstract

“…In recent years, the flavonoids and non-flavonoids phenolics, in all their types and structures (Figure 1), obtained from tropical fruits and their coproducts have aroused the interest of different fields, such as biomedical science and food technology. This interest in these bioactive compounds is due to their numerous biological effects including antioxidant [12,13], hypo-cholesterolemic [14,15], anticancer [16,17], immunomodulatory [18], anti-inflammatory [19,20], anti-diabetic [21,22] and anti-hypertensive [23,24], among others. Figure 1.…”

Section: Introductionmentioning

confidence: 99%

Tropical Fruits and Their Co-Products as Bioactive Compounds and Their Health Effects: A Review

Sáyago‐Ayerdi

García-Martínez

Ramírez-Castillo

et al. 2021

Foods

View full text Add to dashboard Cite

Tropical and subtropical fruits are recognized as a source of a high content of bioactive compounds and health promoting properties due to their nutritional composition. These beneficial health effects are related to the content of several of these bioactive compounds, mainly flavonoids and non-flavonoid phenolics. Many of these compounds are common in different tropical fruits, such as epicatechin in mango, pineapple, and banana, or catechin in pineapple, cocoa or avocado. Many studies of tropical fruits had been carried out, but in this work an examination is made in the current literature of the flavonoids and non-flavonoid phenolics content of some tropical fruits and their coproducts, comparing the content in the same units, as well as examining the role that these compounds play in health benefits.

show abstract

In Vitro Antioxidant, Anti-Inflammatory And Anti-Microbial Activity of Carica Papaya Seeds

Cited by 9 publications

References 0 publications

Carica papaya L. Leaves: Deciphering Its Antioxidant Bioactives, Biological Activities, Innovative Products, and Safety Aspects

Carica papaya L. Leaves: Deciphering Its Antioxidant Bioactives, Biological Activities, Innovative Products, and Safety Aspects

Effect of Roasting Process on Antioxidant Activity of Carica Seeds Coffee (Carica pubescens)

Tropical Fruits and Their Co-Products as Bioactive Compounds and Their Health Effects: A Review

Contact Info

Product

Resources

About