In vitro Antioxidant and Chemical Constituents from the Leaves of 
 Ormocarpum cochinchinense Elumbotti

Sivakumar, T.; Gajalakshmi, D.

doi:10.3923/ajpp.2013.114.122

Cited by 8 publications

(9 citation statements)

References 6 publications

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“…The ethanol extracts showed best antioxidant activity and contained a high amount of flavonoids, tannins and saponins. Compared to an earlier study, where chloroform extract contained varied phytochemicals and showed significant antioxidant activity [15], the chloroform extract in this study contained sterols alone and showed very less antioxidant activity. In earlier studies on the antioxidant activity of O. cochinchinense methanol, chloroform and ethyl acetate extracts showed more activity than ethanol rather in the present study ethanol tops the chart followed by acetone and ethyl acetate [15].…”

Section: Discussioncontrasting

confidence: 82%

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A Comparative Study on the Effect of Solvents on the Phytochemical Profile and Biological Potential of Ormocarpum Cochinchinense Auct. Non (Lour.) Merrill

Hepsibah¹,

Jothi²

2016

Int J Pharm Pharm Sci

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Objective: Plants contain different classes of phytochemicals which have different levels of solubility in solvents, based on their polarity. Hence, this study aims to compare the effects of various solvents on the phytochemical profile and biological potential of Ormocarpum cochinchinense. The present study is the first to evaluate the antifungal activity of the plant.Methods: The sequential extraction was carried out using two sets of solvent systems namely hexane, ethyl acetate, ethanol and chloroform, acetone, methanol. The extracts were subjected to standard phytochemical analysis, antimicrobial activity by disc diffusion method against eight bacteria and six fungi and antioxidant activity by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay.Results: Varied range of phytochemicals was found in the extracts. Acetone extract was rich in phenolic compounds, whereas terpenoids were extracted only in methanol. Acetone extracts showed highest antibacterial activity with a maximum zone of 14.5 mm against Shigella flexineri whereas ethyl acetate extract showed the best antifungal activity with the highest zone of inhibition of 12 mm against Trichophyton menta agrophytes. Hexane and chloroform extracts did not show any antimicrobial activity. For DPPH assay, the ethanol extracts showed the highest percentage inhibition of 92.87%. Conclusion: The present investigation on the plant O. cochinchinense has proved that the selection of solvent for extraction should be based on the target compounds and their bioactivity and concludes that acetone was the best for the extraction of antibacterial compounds and ethyl acetate for antifungal compounds whereas, ethanol was the best for extracting antioxidant compounds in O. cochinchinense.

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Section: Discussioncontrasting

confidence: 82%

“…Some of the pharmacological properties such as bone fracture healing activity [14] antioxidant activity of the leaf fraction [15] and antibacterial properties of leaves [16] of this plant have been reported.…”

Section: Introductionmentioning

confidence: 99%

A Comparative Study on the Effect of Solvents on the Phytochemical Profile and Biological Potential of Ormocarpum Cochinchinense Auct. Non (Lour.) Merrill

Hepsibah¹,

Jothi²

2016

Int J Pharm Pharm Sci

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“…Because of scavenging power, antioxidants turn to be effective in managing with disease like ulcer, stomach problems, cancer and AIDS. Antioxidant when reacts with nitric oxide forms peroxynitrite which can produce toxic radicals such as hydroxyl radicals (Halliwell, 1997;Sivakumar and Gajalakshmi, 2013). When compared the antioxidant activity of SNPs with standard ascorbic acid, it was found that antioxidant activity of nanoparticles was lower than standard in the DPPH free radicals scavenging assay.…”

Section: Discussionmentioning

confidence: 99%

Tuber Extract Mediated Biosynthesis of Silver Nanoparticles and its Antioxidant, Antibacterial Activity

Sivakumar¹,

Gajalakshmi²,

Subramania³

et al. 2015

J. of Biological Sciences

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A B S T R A C TThe biosynthesis of silver nanoparticles by the reduction of aqueous silver metal ions during revelation to both fresh, dry tuber extract and in vitro antioxidant, antibacterial activity of sweet potato were studied. Tuber extract of sweet potato was prepared for the synthesis of silver nanoparticles under different reaction time. The prepared materials were characterized by UV-visible spectroscopy, X-Ray Diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FT-IR). During incubation period, the intensity of colour increased and its characteristic absorption was recorded at 428 and 439 nm. X-ray diffraction showed that the average particles size 4.77 and 5.6 nm. The FT-IR spectra of the tuber extract and synthesized silver nanoparticles revealed the reducing and capping actions of biomolecules such as amine, peptide, amide, lactone, polyphenol groups in protein linkages and it was found to be involved in the stabilization and biosynthesis of AgNPs. Scanning Electron Microscopy (SEM) showed silver nanoparticles was pure and the sizes were ranging from 1-10 µm. Green synthesized silver nanoparticles exhibited strong antioxidant and effective antibacterial activity against human pathogenic bacteria. Thus, green synthesis seems to be cost effective and alternate to conventional methods of silver nanoparticles synthesis. No synthetic reagent were used in this investigation and thus it is an environmentally safe method with potential for biomedical and agriculture application.

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“…The shoot and flower extract of G. superba showed negative results for terpenoids and saponins as reported in Solanum torvum [20]. The tuber extract showed positive results for terpenoids, alkaloids, saponins, and sterols, phenols as mentioned in sweet potato, Asparagus racemosus, elumpotti, Ormocarpum cochinchinense, Datura, Camellia sinensis, and Guazuma ulmifolia [21][22][23][24][25][26][27][28].…”

Section: Qualitative Phytochemical Analysismentioning

confidence: 99%

Phytochemical Analysis and Evaluation of Antimicrobial Activity in the Whole Plant Extracts of Gloriosa Superba

Chimahali¹,

Jebamalar

Gajalakshmi³

et al. 2019

Asian J Pharm Clin Res

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Objectives: The aim of this research work was to carry out the phytochemical screening and to evaluate the antibacterial and antifungal activity of the whole plant extract (shoot, flower, and tuber) of the flame lily (Gloriosa superba). Materials and Methods: In the current work, phytochemicals were extracted from different parts of the plant using different solvents dimethyl sulfoxide, ethyl acetate, and ethanol (ETOH). These phytochemicals contained alkaloids, flavonoids, terpenoids, tannins, saponins, aromatic acids, phenolic compounds, xanthoproteins, triterpenoids, amino acids, philobatinins, carbohydrate, reducing sugar, and proteins and they were separated using standard methods. Furthermore, antimicrobial activities of methanolic separation were determined using various species of bacteria and fungi. Agar well diffusion method was used for the antimicrobial activity and the zone of the inhibition was analyzed. Results: The evaluation of preliminary phytochemical screening of extracts indicated the presence of carbohydrates, reducing sugars, proteins, amino acids, steroids, flavonoids, terpenoids, saponins, alkaloids, tannins, and phlobatannins. Tuber extracts highlighted effective antibacterial and antifungal activities compared with shoot and flower extracts against all the tested bacteria and fungi. ETOH extract of the tuber observed highest antibacterial activity against Staphylococcus aureus (19 mm), followed by Escherichia coli (18 mm), Micrococcus luteus (17 mm), Pseudomonas aeruginosa (17 mm), and Salmonella abony (16 mm) when compared to shoot and flower extracts. G. superba tuber extracts highlighted effective antifungal activities compared with shoot and flower extracts against all the tested fungi. ETOH extract of the tuber observed highest antifungal activity against Rhizopus oryzae (20.17 mm), followed by Mucor Sp. (19.87 mm), Aspergillus niger (18.02), Candida krusei (17.98 mm), and Candida albicans (16.88 mm) as compared to shoot and flower extracts. Conclusion: Results of the current studies flame lily ETOH extracts showed that the plant has significant antimicrobial activities. The strong antibacterial and antifungal activities of flame lily are due to the presence of tannins and flavonoids present in.

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In vitro Antioxidant and Chemical Constituents from the Leaves of Ormocarpum cochinchinense Elumbotti

Cited by 8 publications

References 6 publications

A Comparative Study on the Effect of Solvents on the Phytochemical Profile and Biological Potential of Ormocarpum Cochinchinense Auct. Non (Lour.) Merrill

A Comparative Study on the Effect of Solvents on the Phytochemical Profile and Biological Potential of Ormocarpum Cochinchinense Auct. Non (Lour.) Merrill

Tuber Extract Mediated Biosynthesis of Silver Nanoparticles and its Antioxidant, Antibacterial Activity

Phytochemical Analysis and Evaluation of Antimicrobial Activity in the Whole Plant Extracts of Gloriosa Superba

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