In vitro antimicrobial activity of traditional plant used in mestizo shamanism from the Peruvian amazon in case of infectious diseases

Abstract

Context:Our survey was performed near Iquitos (Peruvian Amazon) and its surroundings and leads us to consider Mestizo ethnomedical practices. The plant species reported here are traditionally used for ailments related to microbial infections. Inhabitants of various ethnic origins were interviewed, and 52 selected plants extracts were evaluated for their antimicrobial properties against a panel of 36 sensitive and multi-resistant bacteria or yeast. The study aimed at providing information on antimicrobial plant extract activities and the ethnomedical context of Mestizo riverine populations from Loreto (Peru).Material and Method:The minimum inhibitory concentrations (MICs) of the plant crude extracts were carried out using the agar dilution method and ranged between 0.075 and 5.0 mg/ml.Results:Of the 40 plants analyzed, 9 species showed MIC ≤0.3 mg/ml (Anacardium occidentale, Couroupita guianensis, Croton lechleri, Davilla rugosa, Erythrina amazonica, Jacaranda copaia subsp. Spectabilis, Oenocarpus bataua, Peperomia macrostachya, and Phyllanthus urinaria) for one or several of the 36 microorganisms and only 6 drug extracts were inactive. Among the 40 plants, 13 were evaluated for the first time for an antibacterial activity.Conclusion:This evaluation of the antimicrobial activity of 40 plants using an approved standard methodology allowed comparing those activities against various microbes to establish antimicrobial spectra of standardized plant extracts, and give support to the traditional use of these plants. It may also help discovering new chemical classes of antimicrobial agents that could serve against multi-resistant bacteria.SUMMARY This study leads us to consider Mestizo ethnomedical practices near Iquitos (Peruvian Amazon) and its surroundings. The plant species reported here are traditionally used for ailments related to microbial infections. 52 selected plants extracts were evaluated for their antimicrobial properties against a panel of 36 sensitive and multi resistant bacteria or yeast. The study aimed at providing information on antimicrobial plant extract activities and the ethnomedical context of Mestizo riverine populations from Loreto.

Review of future insights of Dragon's Blood in dermatology

“…C. lechleri displayed MIC in every bacterial strain (Table ). Of the 40 Amazonian plants investigated, C. lechleri displayed a MIC ≤ 0.03 mg/ml in one or more strains (Roumy et al, ).…”

“…Although C. lechleri displayed antimicrobial, antifungal, and antiviral activity, existing efficacious agents limit Dragon Blood's clinical implication in dermatology (Gurgel et al, ; Orozco‐Topete et al, ; Roumy et al, ). Its spectrum of phytochemicals offers further exploration for its future implications.…”

Antibacterial magnetic nanoparticles for therapeutics: a review

“…Over the past centuries, many plants have been introduced in traditional medicine practises to treat diseases and infections. They are known to possess a wide variety of medicinal properties such as their antibiotic, antioxidant and wound healing qualities [54, 55]. Couroupita guianensis leaves, for instance, are traditionally known as the cure for skin diseases and malaria [56, 57].…”

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“…[2] In addition, the long-standing empirical use of herbal medicine against infectious ailments is consistent with the previous observation. [3] At this point, natural products have garnered substantial interest as lead sources for identification of new pharmaceutical agents. [4] Cashew (Anacardium occidentale L.) is well-known species belongs to the Anacardiaceae family, which is a ORIGINAL ARTICLE perennial-flowering plant and originates from Brazil.…”