In vitro Antimicrobial Activity of Crude Extracts of Some Medicinal Plants from Al-Baha Region in Saudi Arabia

Abstract

Abstract:Medicinal plants are the wealthy source of antibacterial agents and curatives. There is an urgent need for new antimicrobial agents, so the antimicrobial activity for Ruta graveolens L. and Ficus carica Linn. Crude extracts were evaluated for its inhibitory activity against some disease causing selected microorganisms. Root extract of Ruta graveolens L gave 8 and 7 mm inhibition zone against Escherichia coli 254607 and Pseudomonas aeruginosa 254992 respectively. Latex of Ficus carica Linn plants showed that it is a good inhibitor for Candida albicans 254625; whereas the rest of microorganisms (Escherichia coli 254607, Proteus mirabilis 257440, Microsporium canis, Staphylococcus aureus 254996, Klebsiella pneumoniae 254656 and Staphylococcus epidermidis 254997) gave almost a similar inhibition zone around 2-3 mm. The tested crude extract from Ruta graveolens L. and Ficus carica Linn. have proved to be promising treating agents against the tested pathogenic microbes, but it needs to be concentrated and furthermore evaluated.

"Evaluation of the Phenolic Contents, Antioxidant and Antimicrobial Activities of Leaves Extracts of Ruta Graveolens"

“…Kumar, et al [58] noticed an important antibacterial activity against Pseudomonas aeruginosa (P. aeruginosa) only with the methanolic extract from R. graveolens' leaves (from India). Ethyl acetate Root extract of R. graveolens gave a good antibacterial activity against P. aeruginosa (7 mm) and E. coli (8 mm) [59].…”

Antibacterial Effect of Some Palestinian Plant Extracts against Clinical Multidrug-Resistant Gram- Negative Bacteria: A possible synergism with antibiotics

“…There has been an increasing incidence of multiple antibiotic resistances in human pathogenic microorganisms in recent years, largely due to indiscriminate use of commercial antibacterial drugs commonly employed in the treatment of infectious diseases, which have led to the emergence of new bacterial strains that are multi-drug resistant which have resulted in increase in morbidity, mortality and creates enormous health problems. However, the situation is alarming in developing as well as developed countries due to indiscriminate use of antibiotics [3][4][5]54 . The development of drug resistance as well as the appearance of side effects of certain antibiotics has led to the search of new antimicrobial agents mainly among plant extracts with the goal to discover new chemical structures which overcome the above disadvantages [6][7][8][9] .…”

Antimicrobial activity of extracts from olive and basil leaves against pathogenic microbial isolates from outpatient clinics of the Research Institute of Ophthalmology

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