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Objectives: The present study was designed to screen the antibacterial and synergistic effects of Allium sativum, Ecballiumelaterium, Pelargoniumgraveolens, Rosmarinusofficinalis, Phagnalonrupestre and Rutagraveolens plant extracts and essential oils against the followingclinical multidrug-resistant(MDR) Gram negative pathogenic isolates: Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. Methods: All extracts and essential oils were screened for their antibacterial activity and synergistic effect in combination with known antibiotics.The minimum inhibitory concentrations (MICs) and the minimum bactericidal concentrations (MBCs) of the plant extracts were assessed. Results: Our results revealed that, the average diameter of inhibition zones ranged from: 7-14 mm, 7-17 mm, 8-17 mm and 7-13 mm for water, ethanol, methanol and EOs extracts, respectively. The MICs and MBCs were determined for extracts which showed antibacterial activity. The average MICs values ranged from 1.6-100 mg/ml, 1.6-50 mg/ml, 0.39 -50 mg/ml and 3.13-100 μl/ml for water, ethanol, methanol and EOs extracts, respectively. While MBCs values ranged from 25->200 mg/ml, 25- 200 mg/ml and 50->200 μl/ml for water, ethanol, methanol and EOs extracts, respectively. The antibacterial activity of the afore mentioned plant extracts combined with Ciprofloxacin (CIP), Ampicillin (AM), Cefotaxime (CTX), Nalidixic acid (NA), Norofloxacin (NOR), Cefuroxime (CXM), Cefaclor (CF), Ofloxacin (OFX), Cefalexin (CL), Tetracycline (TE), Rifampicin (RIF), Amoxyclav (AMC) and Amikacin (AK) had different degrees of synergism against the selectedbacteria.Essential oils (Eos) of screened plants had the best synergism with antibiotics than the plant extracts against the tested bacteria. The best synergism was noticed in the Eos of A. sativum, P. graveolens and R. officinalis. Conclusion: It was concluded that the synergistic effect of antibiotics and plant extracts is promising approach fortreating infectious diseases caused byMDR Gram negative bacteria. Bangladesh Journal of Medical Science Vol.19(3) 2020 p.509-519

The aim of this study is to assess dyslipidemia status among hypertensive pregnant women and to correlate with preeclampsia in Gaza Strip. A cross sectional study was conducted on 85 pregnant women attending the Gynecology and Obstetrics Department of tertiary care in Gaza Strip (49-hypertension pregnant woman as patients and 36 normal pregnant women without hypertension as a control). Pregnancy induced hypertension (PIH) was found to be associated with fetus sex and it was higher with male fetus 28.6 % and twins 12.2% compared with control. The majority of the PIH patient were obese BMI (32.9 ±4.6) compared with control (25.7±3.5) (P < 0.001). Serum cholesterol, triglycerides, LDL-C, among PIH patients were high (175.3±56.6, 226.9±130.1, 67.4±51.4 mg/dl) respectively, compared with control (143.8±44.1, 186.3 ±101.3, 48.9±46.5 mg/dl) respectively. Abnormal lipid profile and low HDL-C levels may add to the promotion of vascular dysfunction during pregnancy and may induce hypertension and eventually pre-eclampsia and serious complications of fetus.

Background: COVID-19 is an emerging infectious disease that affected multiple countries and sustained person-to-person transmission making it a concerning and serious public health threat. This pandemic has emphasized that good nutrition and a healthy life is the key to strengthening immunity. Aim of the study: To assess knowledge of nutrition toward the COVID-19 among the Palestinian population. Methods: A cross-sectional online survey was launched at West Bank and Gaza Strip. A total number of 554 participants have shared the completion of this survey and the response rate was 90.2%. Results: The mean level of knowledge among participants was 65.38% and the study indicated that 55.8% behaving healthy nutritional habits. The analysis revealed that the mean score of knowledge increased by 1.61 comparing the oldest age groups (>30 years) against the youngest group. As the same as, the knowledge mean score increased by 2.46 among the obese individuals according to BMI classification (>30). Whereas, the knowledge mean score was increased significantly among those who work in medical sectors compared to others unemployed individuals. As well, the knowledge score increased by 2.04 among individuals with comorbidity than healthy ones. Conclusion: Nutritional knowledge score during COVID-19 was 67.03% and the knowledge about the body immunity system and the protective measures against COVID-19, scored a weighted mean of 76.21%. The level of knowledge among all participants did not reflect a satisfactory level of knowledge among the public regard COVID-19 while the level of behaving healthy nutritional habits illustrated that nearly 45% of the participants were practicing unhealthy nutritional behaviors. Bangladesh Journal of Medical Science Vol. 22 No. 01 January’23 Page : 57-67