In vitro antimicrobial activity of Caesalpinia ferrea Martius fruits against oral pathogens

Sampaio, Fábio Correia; Pereira, Maria do Socorro Vieira; Dias, Celidarque S.; Costa, Vicente Carlos O.; Conde, Nikeila C. O.; Buzalaf, Marília Afonso Rabelo

doi:10.1016/j.jep.2009.04.034

Cited by 107 publications

(90 citation statements)

References 37 publications

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“…Anti-infl ammatory, analgesic and antimicrobial properties have been demonstrated, causing interest in continuing with analysis of its pharmacological and therapeutic characteristics [9][10][11][12] . Studies with L. ferrea have demonstrated promising results, and there is a perspective for its use as a mouth wash for dental biofi lm control, because it has antibacterial activity against the microorganisms present in the oral cavity 10,12 .…”

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confidence: 99%

Herbal mouthwash based on Libidibia ferrea: microbiological control, sensory characteristics, sedimentation, pH and density

Venâncio

Rodrigues

Souza

et al. 2015

Rev. odontol. UNESP

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Introduction Phytotherapy is the study of herbal medicines and their applicability to cure diseases in general, being a therapeutic method which can be used for the prevention and treatment of mouth diseases. Among the herbal studied, the Libidibia ferrea, known as jucá or ironwood, is widely used in folk medicine by presenting anti-inflammatory, analgesic, antimicrobial and antipyretic therapeutic properties. Objective To evaluate in vitro pharmacological stability of the Libidibia ferrea extract’s mouthwash (INPA - 228 022). Material and method It was held the mouthwash microbiological control by determining the total number of microorganisms and Salmonella sp, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus; stability characteristics (color, odor, brightness and consistency), sedimentation test (centrifuge), the pH measurement (pH meter) and density evaluation (pycnometer) were analyzed. Result The mouthwash showed to be absent from microorganisms and no changes were observed in the organoleptics and sedimentation characteristics. The average pH values were 6.21, 6.15 and 5.85 at 0, 30 and 60 days, respectively, and 1.029, 1.033 and 1.035 g/ mL density values, respectively, without interfering with the final characteristic of the formulation. Conclusion The mouthwash presented pharmacological stability and quality conditions.

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mentioning

confidence: 99%

Herbal mouthwash based on Libidibia ferrea: microbiological control, sensory characteristics, sedimentation, pH and density

Venâncio

Rodrigues

Souza

et al. 2015

Rev. odontol. UNESP

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“…Spelman et al [20] studied the jambu (Spilanthes acmella), and the findings provided the first evidence supporting the use of the plant against malaria and showing that it has active ingredients against Plasmodium falciparum.…”

Section: Discussionmentioning

confidence: 99%

Atividade antimicrobiana in vitro de plantas da Amazônia sobre alguns micro-organismos formadores do biofilme dental

Conde

Pereira

Bandeira

et al. 2015

Rev. Odonto Ciênc. (Online)

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“…Hence, inhibition of glucosyltransferases by PA in turn inhibits caries. 7,10,11 Bioflavanoids from other sources have also been demonstrated to inhibit other oral Streptococci, Actinomycetes and Lactobacilli at concentrations of 1.56 to 6.25 mg/mL. 12 Grape seed extracts inhibit the growth of anaerobic bacteria, such as Porphyromonas gingivalis and Fusobacterium nucleatum, associated with periodontal disease.…”

Section: Discussionmentioning

confidence: 99%

Grape Seed Extract as a Potential Remineralizing Agent: A Comparative in vitro Study

Benjamin

Sharma²,

Thomas³

et al. 2012

The Journal of Contemporary Dental Practice

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Objective: Remineralization is an effective treatment that may stop or reverse early tooth decay. Grape seed extract (GSE) is the potential remineralizing agent under investigation. Materials and methods:Sound human tooth sections were obtained from the cervical portion of the root and stored in demineralizing solution at 37°C for 96 hours to induce artificial root caries lesions. The sections were divided into four treatment groups including 6.5% grape seed extract, sodium monofluorophosphate (220 ppm) with 0.05% calcium glycerophosphate, 0.5% calcium glycerophosphate and control (no treatment). An in vitro pH cycling model was used to cycle the demineralized specimens through treatment solutions, acidic buffer and neutral buffer for 8 days at 6 cycles per day. Subsequently, they were evaluated using confocal laser scanning microscope. Data were analyzed using analysis of variance (p < 0.05).Results: GSE revealed less demineralization and more remineralization compared with other groups. Conclusion: GSE promotes remineralization of artificial root caries lesions.Clinical significance: The search for the perfect remineralizing agent continues to this day. GSE could be a welcome addition to the remineralization armamentarium.

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In vitro antimicrobial activity of Caesalpinia ferrea Martius fruits against oral pathogens

Abstract: Caesalpinia ferrea fruit extract can inhibit in vitro growth of oral pathogens in planktonic and biofilm models supporting its use for oral infections.

Cited by 107 publications

References 37 publications

Herbal mouthwash based on Libidibia ferrea: microbiological control, sensory characteristics, sedimentation, pH and density

Herbal mouthwash based on Libidibia ferrea: microbiological control, sensory characteristics, sedimentation, pH and density

Atividade antimicrobiana in vitro de plantas da Amazônia sobre alguns micro-organismos formadores do biofilme dental

Grape Seed Extract as a Potential Remineralizing Agent: A Comparative in vitro Study

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