In-vitro antimicrobial activity and complement/macrophage stimulating effects of a hot-water extract from mycelium of the oyster mushroom Pleurotus sp.

Llauradó, Gabriel; Morris, Humberto J.; Ferrera, Leodán; Camacho, Miladis; Castán, Leniher; Lebeque, Yamila; Beltrán, Yaixa; Cos, Paul; Bermúdez, Rosa C.

doi:10.1016/j.ifset.2015.05.002

Cited by 13 publications

(14 citation statements)

References 44 publications

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“…The extract (5-100 µg/well) enhanced the acid phosphatase activity in murine peritoneal macrophages by 133-184% compared to controls. The findings introduce a novel "bifunctional" approach Llauradó et al (2015) 44 (antimicrobial-immunomodulatory) to the nutraceutical potential of the Pleurotus hot-water mycelial extract.…”

Section: Pleutorus Sppmentioning

confidence: 99%

Biotechnological, nutritional and therapeutic uses of Pleurotus spp. (Oyster mushroom) related with its chemical composition: A review on the past decade findings

Corrêa

Brugnari

Bracht

et al. 2016

Trends in Food Science & Technology

169

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Section: Pleutorus Sppmentioning

confidence: 99%

Biotechnological, nutritional and therapeutic uses of Pleurotus spp. (Oyster mushroom) related with its chemical composition: A review on the past decade findings

Corrêa

Brugnari

Bracht

et al. 2016

Trends in Food Science & Technology

169

View full text Add to dashboard Cite

show abstract

“…cytotoxicity on cancer cells, health-giving), potentially offers a route to safer foods with enhanced health-imparting characteristics. This approach makes use of the potential for ''bifunctional'' effects [24] of glucan materials derived from traditional food sources, including some species of mushrooms [21]. These natural foods have been shown to be a relatively unexplored source for improvements in food safety, preservation while providing extra health benefits [40].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Properties and Cytotoxicity of Sulfated (1,3)-��-D-Glucan from the Mycelium of the Mushroom Ganoderma lucidum

Wan‐Mohtar

Young

Abbott

et al. 2016

Journal of Microbiology and Biotechnology

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Ganoderma lucidum BCCM 31549 has a long established role for its therapeutic activities. In this context, much interest has focused on the possible functions of the (1,3)-β-D-glucan (G) produced by these cultures in a stirred-tank bioreactor and extracted from their underutilized mycelium. In the existing study, we report on the systematic production of G, and its sulfated derivative (GS). The aim of this study was to investigate G and its GS from G. lucidum in terms of their antibacterial properties and cytotoxicity spectrum against human prostate cells (PN2TA) and human caucasian histiocytic lymphoma cells (U937). (1)H NMR for both G and GS compounds showed β-glycosidic linkages and structural similarities when compared with two standards (laminarin and fucoidan). The existence of characteristic absorptions at 1,170 and 867 cm(-1) in the FTIR (Fourier Transform Infrared Spectroscopy) for GS demonstrated the successful sulfation of G. Only GS exhibited antimicrobial activity against a varied range of test bacteria of relevance to foodstuffs and human health. Moreover, both G and GS did not show any cytotoxic effects on PN2TA cells, thus helping demonstrate the safety of these polymers. Moreover, GS showed 40% antiproliferation against cancerous U937 cells at the low concentration (60 μg/ ml) applied in this study compared with G (10%). Together, this demonstrates that sulfation clearly improved the solubility and therapeutic activities of G. The water-soluble GS demonstrates the potential multifunctional effects of these materials in foodstuffs.

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“…In fact, numerous bioactive compounds with antimicrobial activity have been identified from the fruiting bodies, cultured mycelia and culture filtrates of Pleurotus ssp. and include polysaccharides (Llauradó et al, 2015), fatty acid esters (Suseem and Saral, 2013) and an organic acid identified as 3-(2-aminophenylthio)-3-hydroxypropanoic (Younis et al, 2015).…”

Section: Antifungal Testmentioning

confidence: 99%

Effects of Carbon Sources and Time of Cultivation on the Antimicrobial Activities of Intra and Extracellular Extracts of Pleurotus Pulmonarius Cultured in Submerged Conditions

Silva¹,

Abrahão²,

Peralta³

2016

Int.J.Curr.Microbiol.App.Sci

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In-vitro antimicrobial activity and complement/macrophage stimulating effects of a hot-water extract from mycelium of the oyster mushroom Pleurotus sp.

Cited by 13 publications

References 44 publications

Biotechnological, nutritional and therapeutic uses of Pleurotus spp. (Oyster mushroom) related with its chemical composition: A review on the past decade findings

Biotechnological, nutritional and therapeutic uses of Pleurotus spp. (Oyster mushroom) related with its chemical composition: A review on the past decade findings

Antimicrobial Properties and Cytotoxicity of Sulfated (1,3)-��-D-Glucan from the Mycelium of the Mushroom Ganoderma lucidum

Effects of Carbon Sources and Time of Cultivation on the Antimicrobial Activities of Intra and Extracellular Extracts of Pleurotus Pulmonarius Cultured in Submerged Conditions

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