In vitro Antifungal Potentials of Hamelia patens Jacq. (Rubiaceae) Aqueous Extracts of Leaves, Flowers and Fruits

Abstract

Genetic variation provides the foundation for species to respond to changes in the natural environment. Self fertilization is a common mating system in plants, and is known to reduce genetic diversity; increase genetic structure and potentiality put population at greater risk of extinction. Hamelia patens Jacq. is an exotic ornamental plant, widely distributed in Indian garden. Even though the plant flowers throughout the year, it never produces seeds, and hence genetic diversity is lacking in this taxon. From the previous analysis it was found that, gametophytic self-incompatibility is operating in this plant. In the present study, 14 accessions of H. patens were collected from different parts of Kerala and found that, accession No.3 has significant morphological differences compared to other accessions. Crossing between morphologically similar plants from various localities failed to set-seeds, whereas crosses between morphologically dissimilar plants always set-seeds. This species have both self-incompatible (on selfing) and compatible (crossing) populations, and are there for ideal for understanding how the mating system affect genetic diversity and structure. In the present study, morphologically different plant shows genetic variability which is confirmed by random amplified polymorphic DNA analysis.

A Phytochemical and Ethnopharmacological Recapitulation on Hamelia patens

“…10 % concentration of fruit, leaf and flower extract cause 100 % inhibition of Fusarium oxysporum, Rhizo itonia solani. 100 % concentration of leaf, fruit and flower extract is comparable with the positive control, bavistin 0.5 % [45]. Another study also explained that Candida albicans was more susceptible to ethanolic extract than the Aspergillus Niger among the fungal isolates where Minimum Fungicidal Concentration (MFC) ranged from 25 mg/ml to > 100 mg/ml [43].…”

Avaliação da ação antioxidante e citotoxicológica do extrato etanólico de Hamelia patens Jacq. em células NIH 3T3

“…A principal função da H. patens é a ação anti-inflamatória. Há relatos também de melhoras em casos de diarreia, picada de mosquitos, cólicas menstruais e atividade citotóxica contra linhagem de células tumorais (ABUBACKER et al, 2013). Pesquisas realizadas em vários países têm mostrado que os extratos desta planta possuem propriedades bactericidas e antifúngicas (MARTINEZ & PACHECOII, 2008).…”

Identificação de fungos endofíticos em Hamelia patens Jacq. e avaliação do potencial antimicrobiano dos extratos fúngicos

“…Pesquisas revelaram o potencial terapêutico da planta, no controle de fungos oportunistas como C. albicans e Aspergillus sp (Abubacker et al, 2013). Também apresentou atividade citotóxica relevante frente a células do adenocarcinoma cervical e carcinoma escamoso do útero (Mena-Rejon et al, 2009).…”