In vitro and in vivo comparison of argon-pumped and diode lasers for photodynamic therapy using second-generation photosensitizers

Hammer‐Wilson, Marie J.; Sun, Carlos; Ghahramanlou, Marjan; Berns, Michael W.

doi:10.1002/(sici)1096-9101(1998)23:5<274::aid-lsm7>3.0.co;2-o

Cited by 15 publications

(5 citation statements)

References 10 publications

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“…Now, several new types of laser light sources for PDT are available, 34,35 such as 532‐nm frequency‐doubled neodymium‐doped yttrium aluminum garnet (Nd:YAG), semiconductor, and helium‐neon (He‐Ne) lasers. These new lasers have several advantages over the copper vapor and argon ion lasers, including smaller volume, easier manipulation, and lower maintenance costs 36 . Currently, our group mostly uses the frequency‐doubled Nd:YAG lasers, including continuous wavelength and pulsed frequency‐doubled Nd:YAG lasers, for PWS PDT.…”

Section: Light Sourcesmentioning

confidence: 99%

Twenty Years of Clinical Experience with a New Modality of Vascular-Targeted Photodynamic Therapy for Port Wine Stains

Qiu

Wang

et al. 2011

Dermatologic Surgery

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Section: Light Sourcesmentioning

confidence: 99%

Twenty Years of Clinical Experience with a New Modality of Vascular-Targeted Photodynamic Therapy for Port Wine Stains

Qiu

Wang

et al. 2011

Dermatologic Surgery

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“…Wavelengths from UV to infrared can be obtained. Fluorescence diagnostics and PDT are typical application fields [75,76].…”

Section: Diode Lasersmentioning

confidence: 99%

Lasers in medicine

et al. 2008

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It is hard to imagine that a narrow, one-way, coherent, moving, amplified beam of light fired by excited atoms is powerful enough to slice through steel. In 1917, Albert Einstein speculated that under certain conditions atoms could absorb light and be stimulated to shed their borrowed energy. Charles Townes coined the term laser (light amplification by stimulated emission of radiation) in 1951. Theodore Maiman investigated the glare of a flash lamp in a rod of synthetic ruby, creating the first human-made laser in 1960. The laser involves exciting atoms and passing them through a medium such as crystal, gas or liquid. As the cascade of photon energy sweeps through the medium, bouncing off mirrors, it is reflected back and forth, and gains energy to produce a high wattage beam of light. Although lasers are today used by a large variety of professions, one of the most meaningful applications of laser technology has been through its use in medicine. Being faster and less invasive with a high precision, lasers have penetrated into most medical disciplines during the last half century including dermatology, ophthalmology, dentistry, otolaryngology, gastroenterology, urology, gynaecology, cardiology, neurosurgery and orthopaedics. In many ways the laser has revolutionized the diagnosis and treatment of a disease. As a surgical tool the laser is capable of three basic functions. When focused on a point it can cauterize deeply as it cuts, reducing the surgical trauma caused by a knife. It can vaporize the surface of a tissue. Or, through optical fibres, it can permit a doctor to see inside the body. Lasers have also become an indispensable tool in biological applications from high-resolution microscopy to subcellular nanosurgery. Indeed, medical lasers are a prime example of how the movement of an idea can truly change the medical world. This review will survey various applications of lasers in medicine including four major categories: types of lasers, laser-tissue interactions, therapeutics and diagnostics.

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“…Light is either scattered or absorbed when it enters tissues and the extent of both processes depends on the tissue type and the light wavelength. The traditional argon-dye and copper-dye lasers can be replaced by diode lasers, which are cheaper, very stable, reliable and easily transportable [89]. As a consequence, red light possesses a high penetration power into human tissues.…”

Section: 24mentioning

confidence: 99%

Nanoparticles for Photodynamic Therapy of Cancer

Zeisser‐Labouèbe

Vargas

Delié

2003

Nanotechnologies for the Life Sciences

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The sections in this article are Introduction Concept and Basis of Photodynamic Therapy and Photodetection Mechanisms of Photodynamic Therapy and Photodiagnosis Selective Tumor Uptake of Photosensitizers Photosensitizers Conventional Photosensitizers New Entities Photodynamic Therapy: Advantages and Limitations Photosensitizer Formulations Non‐biodegradable Nanoparticles for Photodynamic Therapy Metallic Nanoparticles Ceramic Nanoparticles Nanoparticles Made of Non‐biodegradable Polymers Biodegradable Polymeric Nanoparticles for Photodynamic Therapy Preparation of Biodegradable Polymeric Nanoparticles In situ Polymerization Dispersion of a Preformed Polymer “Stealth” Particles Targeted Nanoparticles In Vitro Relevance of Polymeric Nanoparticles in PDT on Cell Models Photodynamic Activity of PS ‐loaded Nanoparticles Uptake and Trafficking of Photosensitizers In Vivo Relevance of Polymeric Nanoparticles in PDT Biodistribution and Pharmacokinetics of Photosensitizers Coupled to Nanoparticles Vascular Effects In Vivo Efficacy on Tumor: Tumor Suppression Effects Adverse Effects Conclusions Acknowledgments

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In vitro and in vivo comparison of argon-pumped and diode lasers for photodynamic therapy using second-generation photosensitizers

Cited by 15 publications

References 10 publications

Twenty Years of Clinical Experience with a New Modality of Vascular-Targeted Photodynamic Therapy for Port Wine Stains

Twenty Years of Clinical Experience with a New Modality of Vascular-Targeted Photodynamic Therapy for Port Wine Stains

Lasers in medicine

Nanoparticles for Photodynamic Therapy of Cancer

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