In vitro and in vivo antioxidant activity of exopolysaccharides from endophytic bacterium Paenibacillus polymyxa EJS-3

Liu, Jun; Luo, Jianguang; Ye, Hong; Sun, Yi; Lu, Zhaoxin; Zeng, Xiaoxiong

doi:10.1016/j.carbpol.2010.07.008

Cited by 162 publications

(82 citation statements)

References 29 publications

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“…Antioxidant enzymes, including SOD, GSH-Px and CAT, which could convert active oxygen molecules into nontoxic compounds, formed the first line of defense against ROS in the organism during oxidative stress (Abuja, & Albertini, 2001;Liu et al, 2010). The mechanism may be that SOD could dismutate superoxide radicals to form hydrogen peroxide, which later could be decomposed to water and oxygen by GSH-Px and CAT, thereby the formation of ROS was prevented (Yao et al, 2005).…”

Section: Discussionmentioning

confidence: 98%

Purification, characterization and hepatoprotective activities of mycelia zinc polysaccharides by Pleurotus djamor

Zhang

Liu

Yang

et al. 2016

Carbohydrate Polymers

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Section: Discussionmentioning

confidence: 98%

Purification, characterization and hepatoprotective activities of mycelia zinc polysaccharides by Pleurotus djamor

Zhang

Liu

Yang

et al. 2016

Carbohydrate Polymers

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“…The absorbance was measured at 517 nm ( A 1 ). The absorbance of solvent instead of mycelium extract solution was measured as A 0 and that of sample solution without DPPH solution measured as A 2 (Liu et al 2010). Each sample was determined in triplicate.…”

Section: Methodsmentioning

confidence: 99%

Analysis of radical scavenging active components in the fermented mycelia of Ophiocordyceps formosana

Cheng

Da³

et al. 2017

Mycology

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The rates of 1,1-diphenyl-2-picryhydrazyl (DPPH)-free radical scavenging and hydroxyl radical eliminating were employed as indexes to qualitatively and quantitatively analyse the radical scavenging activity of the extracts with different solvents from fermented mycelia of Hirsutella huangshanensis RCEF0868, the anamorph of Ophiocordyceps formosana (FMOF). The results showed that both the aqueous extract and the methanol extract had significant radical scavenging activity. The half maximal inhibitory concentrations (IC50) of the aqueous extract on DPPH-free radical and hydroxyl radical are 0.85 and 1.37 mg/mL, respectively, while the IC50 of methanol extract is 1.23 and 2.91 mg/mL, respectively. The combined liquid chromatography-diode array detector-high resolution mass spectrometer(HRMS) analysis and activity determination revealed that the molecular formulas of three radical scavengers in aqueous extract were C6H14O6(1), C14H17N5O8(2) and C20H33N5O9(3). In addition to the compound 1, the methanol extract had another three radical scavengers as C30H22O11(4), C30H22O10(5) and C30H18O10(6). All the six kinds of components exhibited the DPPH radical scavenging activity, and compounds 1, 4 and 5 also showed the hydroxyl radical eliminating activity at the same time. By querying the database of natural products and reference to the relevant reports, compound 3 may be a new entity. The others were respectively cordycepic acid, succinoadenosine, 4α-oxyrugulosin, rugulosin and skyrin and, among them, succinoadenosine and 4α-oxyrugulosin were found in entomogenous fungi for the first time.

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“…During centrifugation at 4000 ×g for 10 min, the free Se that was released from the nanoparticles would penetrate the filtrate receiver and was quantitated by hydride generation atomic fluorescence spectrometry (Olson, Palmer, & Cary, 1975). The free radical systems used in this study contain ABTS (Re et al, 1999), DPPH (Xu, & Chang, 2007), ·OH (Yang, Guo, & Yuan, 2008), H 2 O 2 (Liu et al, 2010), lipid peroxide (Tsuda et al, 1994), and superoxide anion (Qiao et al, 2009). …”

Section: Measurement Of Controlled Release Efficiencymentioning

confidence: 99%

Synthesis, characterization, and controlled release of selenium nanoparticles stabilized by chitosan of different molecular weights

Zhang

Zhai

Zhao

et al. 2015

Carbohydrate Polymers

149

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In vitro and in vivo antioxidant activity of exopolysaccharides from endophytic bacterium Paenibacillus polymyxa EJS-3

Cited by 162 publications

References 29 publications

Purification, characterization and hepatoprotective activities of mycelia zinc polysaccharides by Pleurotus djamor

Purification, characterization and hepatoprotective activities of mycelia zinc polysaccharides by Pleurotus djamor

Analysis of radical scavenging active components in the fermented mycelia of Ophiocordyceps formosana

Synthesis, characterization, and controlled release of selenium nanoparticles stabilized by chitosan of different molecular weights

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