In vitro activity of tosufloxacin against bacterial enteric pathogens

Glick, Ellen J.; Segreti, John; Goodman, Larry J.; Trenholme, Gordon M.

doi:10.1016/0732-8893(90)90026-r

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2011

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Cited by 3 publications

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“…The effect of this medicine is 2-4 times stronger than ciprofloxacin while having a lower toxicity to the central nervous system. It has great antibiotic effect on gram-positive, gram-negative and anaerobic bacteria, showing a healing potential of broad spectrum, low toxicity and side effects, and high clinical efficiency [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Analysis of the spectroscopic characteristics on the binding interaction between tosufloxacin and bovine lactoferrin

Guo

Zhang

Lü

et al. 2011

Journal of Luminescence

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Section: Introductionmentioning

confidence: 99%

Analysis of the spectroscopic characteristics on the binding interaction between tosufloxacin and bovine lactoferrin

Guo

Zhang

Lü

et al. 2011

Journal of Luminescence

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99mTc(CO)3-tosufloxacin dithiocarbamate complexation and radiobiological evaluation in male Wister rat model

Shah

Khan

2011

J Radioanal Nucl Chem

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Lomefloxacin

Wadworth¹,

Goa²

1991

Drugs

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The antibacterial efficacy of oral lomefloxacin has been investigated in a wide variety of infections, including respiratory and uncomplicated and complicated urinary tract infections, obstetric, gynaecological, joint, skin, oral, ear, nose, throat and eye infections. It has also been used as an otic solution in patients with otitis media and as an ophthalmic solution in the treatment of eye infections. In clinical trials its efficacy is equivalent to that of other quinolones and it is at least as effective as other antibacterial drugs ordinarily used in these infections. Lomefloxacin offers certain advantages compared with other quinolone antibacterial drugs in that it may be conveniently administered once daily and theophylline dosage adjustment does not appear to be necessary in patients receiving this bronchodilator concomitantly. Thus, orally administered lomefloxacin should prove a useful broad spectrum antibacterial drug for a wide variety of clinical infections.

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In vitro activity of tosufloxacin against bacterial enteric pathogens

Cited by 3 publications

References 16 publications

Analysis of the spectroscopic characteristics on the binding interaction between tosufloxacin and bovine lactoferrin

Analysis of the spectroscopic characteristics on the binding interaction between tosufloxacin and bovine lactoferrin

99mTc(CO)3-tosufloxacin dithiocarbamate complexation and radiobiological evaluation in male Wister rat model

Lomefloxacin

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