In vitro activity of ciprofloxacin, moxifloxacin, vancomycin and erythromycin against planktonic and biofilm forms of Corynebacterium urealyticum

Soriano, Francisco; Huelves, Lorena; Naves, Plínio Lázaro Faleiro; Rodríguez-Cerrato, Violeta; Prado, Gema del; Ruiz, Vicente Ausina; Ponte, Carmen

doi:10.1093/jac/dkn491

Cited by 32 publications

(32 citation statements)

References 23 publications

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“…To the best of our knowledge, this is the first report of variable biofilm formation by different C. striatum strains isolated from blood specimens. Strains might escape from killing by producing robust biofilms, which have been reported to allow microorganisms to exchange genetic material and to become persistent colonizers and/or to gain greater resistance to antibiotics (39). These findings might explain why pattern A strains can survive in hospital patients for months or, even years.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of Multidrug-Resistant <i>Corynebacterium</i> spp. Isolated from Blood Cultures of Hospitalized Patients in Japan

et al. 2017

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Section: Discussionmentioning

confidence: 99%

Characteristics of Multidrug-Resistant <i>Corynebacterium</i> spp. Isolated from Blood Cultures of Hospitalized Patients in Japan

et al. 2017

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“…The following human pathogens were used in this work: Pseudomonas aeruginosa PA01 (Alonso et al 1999), Staphylococcus aureus 6538P (Lima et al 2014), Klebsiella pneumoniae DF12SA (Shahi et al 2013), Acinetobacter baumannii Ab13 (Poirel et al 2008), Burkholderia cenocepacia LMG 16656 and Burkholderia metallica LMG 24068 (Soriano et al 2009). The strains were routinely grown at 37°C in LB medium.…”

Section: Pathogenic Strainsmentioning

confidence: 99%

Identification of a Sorbicillinoid-Producing Aspergillus Strain with Antimicrobial Activity Against Staphylococcus aureus: a New Polyextremophilic Marine Fungus from Barents Sea

et al. 2018

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The exploration of poorly studied areas of Earth can highly increase the possibility to discover novel bioactive compounds. In this study, the cultivable fraction of fungi and bacteria from Barents Sea sediments has been studied to mine new bioactive molecules with antibacterial activity against a panel of human pathogens. We isolated diverse strains of psychrophilic and halophilic bacteria and fungi from a collection of nine samples from sea sediment. Following a full bioassay-guided approach, we isolated a new promising polyextremophilic marine fungus strain 8Na, identified as Aspergillus protuberus MUT 3638, possessing the potential to produce antimicrobial agents. This fungus, isolated from cold seawater, was able to grow in a wide range of salinity, pH and temperatures. The growth conditions were optimised and scaled to fermentation, and its produced extract was subjected to chemical analysis. The active component was identified as bisvertinolone, a member of sorbicillonoid family that was found to display significant activity against Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 30 μg/mL.

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“…The respective data regarding minimal bactericidal concentration (MBC) of vancomycin, moxifloxacin, or ciprofloxacin for C. urealyticum biofilm is about two or three orders of magnitude greater than the MBC of respective planctonic forms (30). Therefore, we aimed to find out whether coryneform bacteria have a proclivity to produce biofilm in vitro .…”

Section: Discussionmentioning

confidence: 99%

Coryneform bacteria in human semen: inter-assay variability in species composition detection and biofilm production ability

Türk¹,

Mazzoli²,

Štšepetova³

et al. 2014

Microbial Ecology in Health & Disease

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BackgroundCoryneform bacteria constitute an important segment of male urogenital microbiota. They have been generally considered as saprophytes, although some species have been associated with prostatitis as well. At the same time, biofilm infections have been suspected as a cause of prostatitis.ObjectiveTo identify a set of coryneform bacteria isolated from semen of either healthy men or prostatitis patients applying different methods to reveal inter-assay variability and to determine their ability of adhesion and biofilm production.DesignCoryneform bacteria were identified by API Coryne 2.0 biochemical identification system and 16S rDNA sequencing using different primer sets. Quantitative assessment of biofilm production was performed using crystal violet binding assay method.ResultsThe most common species were Corynebacterium seminale, C. minutissimum, and Dermabacter hominis. Altogether 14 species and related genera were found. We observed the best inter-assay agreement when identifying C. seminale. Biofilm was observed in 7 out of 24 strains. The biofilm-producing strains belonged to Arthrobacter cumminsii, Dermabacter hominis, C. minutissimum, and Actinomyces neuii. No differences were found between the strains originating from prostatitis patients and healthy men. Dermabacter hominis strains were more potent biofilm producers than C. seminale strains (p=0.048).ConclusionsWe can conclude that a wide variety of coryneform bacteria can be found from the male genital tract, although their exact identification is problematic due to insufficient representation in databases. Nearly one third of the strains are able to form biofilm that may give them an advantage for surviving several host- and treatment-related conditions.

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In vitro activity of ciprofloxacin, moxifloxacin, vancomycin and erythromycin against planktonic and biofilm forms of Corynebacterium urealyticum

Cited by 32 publications

References 23 publications

Characteristics of Multidrug-Resistant <i>Corynebacterium</i> spp. Isolated from Blood Cultures of Hospitalized Patients in Japan

Characteristics of Multidrug-Resistant <i>Corynebacterium</i> spp. Isolated from Blood Cultures of Hospitalized Patients in Japan

Identification of a Sorbicillinoid-Producing Aspergillus Strain with Antimicrobial Activity Against Staphylococcus aureus: a New Polyextremophilic Marine Fungus from Barents Sea

Coryneform bacteria in human semen: inter-assay variability in species composition detection and biofilm production ability

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