In‐use efficacy of a chlorhexidine in alcohol surgical rub: a comparative study

Abstract

The chlorhexidine regimen demonstrated excellent bactericidal efficacy throughout an operating list, and was superior to povidine-iodine scrubbing in all aspects. The alcoholic chlorhexidine regimen is simpler and should have wide surgical application.

Analgesia pós-operatória plexular contínua: estudo dos efeitos colaterais e do risco de infecção dos cateteres

“…Um dos fatores que pode ter contribuído para o melhor resultado seria o uso da solução alcoólica de clorexedina a 0,5% para degermação da pele antes da realização do bloqueio e posicionamento do cateter. A solução de clorexedina parece ser superior à solução de iodo e álcool usada nos outros estudos [29][30][31] . Surpreende ainda o fato que os outros autores tomaram precauções que não foram usadas no método do presente estudo, tais como uso de avental estéril no momento da colocação do cateter e assepsia da pele no momento da retirada do cateter 16,28 .…”

Current Approaches for the Prevention of Surgical Site Infections

“…In a study comparing scrubbing regimens of CHG/alcohol with povidone-iodine, the CHG regimen resulted in a >50-fold reduction in hand bacterial counts. In contrast, the povidone-iodine scrub reduced counts by more than 3-fold [34] . In a similar study of 39 volunteers, scrubbing with CHG/alcohol solutions resulted in a significantly greater reduction in bacterial count compared with povidone-iodine and chloroxylenol scrubs at all sampling times, up to 6 hrs after application (P < 0.01) (Fig.…”

“…CHG products demonstrate a significant immediate and persistent antimicrobial effect, giving them a theoretical advantage during long surgical response to chlorhexidine gluconate (CHG), povidone=iodine (P-I) and chloroxylenol (CX) immediately after application and 3 and 6 hours later on days 1, 2 and 5. Reprinted with permission from Aly and Maibach [35] procedures [31,34] . In a study comparing scrubbing regimens of CHG/alcohol with povidone-iodine, the CHG regimen resulted in a >50-fold reduction in hand bacterial counts.…”

New method for assessing hand disinfection shows that pre-operative alcohol/chlorhexidine rub is as effective as a traditional surgical scrub

“…2,3,4 However, these studies, as well as current US 5 and European 6 hand disinfection guidelines, have potential methodological flaws that may limit their applicability to a working operating theatre environment. These include the need for test subjects to adhere to stringent conditions for days before the studies, 3,5,6 performing baseline studies on a different occasion from the test studies, [2][3][4][5] and testing the products for comparison on a different occasion in each subject. [2][3][4][5][6] As such, a novel method -the McKenzie method -was developed to compare the products in an everyday operating theatre environment using working operating theatre personnel.…”

“…These include the need for test subjects to adhere to stringent conditions for days before the studies, 3,5,6 performing baseline studies on a different occasion from the test studies, [2][3][4][5] and testing the products for comparison on a different occasion in each subject. [2][3][4][5][6] As such, a novel method -the McKenzie method -was developed to compare the products in an everyday operating theatre environment using working operating theatre personnel. With this method, subjects have no special preparation, the test solutions are compared at the same time using sequential glove changes, and the subjects act as their own control.…”