In situ synthesis and characterization of hydroxyapatite/natural rubber composites for biomedical applications

Dick, Teo Atz; Santos, Luís Alberto dos

doi:10.1016/j.msec.2017.03.301

Cited by 40 publications

(19 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hydroxyapatite (HAP), with the ideal formula Ca 10 (PO 4 ) 6 (OH) 2 , is chosen as the target adsorbent in this method. HAP belongs to the apatite family and commonly exists in natural bones and teeth (11)(12)(13)(14). It has salient features in terms of high stability, good biocompatibility, high bioactivity, and high sorption capacity (12,(15)(16)(17).…”

Section: Introductionmentioning

confidence: 99%

“…In the past thirty years, there has been a great interest worldwide in the synthetic methods of HAP powders. As summarized by Fihri (12) those methods are classified into four categories: dry methods (23), wet methods (13,15), microwave-assisted methods (24,25) and miscellaneous methods. Among them, the wet methods, including double decomposition or coprecipitation, emulsion, hydrolysis method, sol-gel method, and hydrothermal approach, are widely adopted since the procedures for these methods are simple and allow perfect control on the structure, texture, and morphology of HAP powders (12).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Preliminary study on the upcycle of non-structural construction and demolition waste for waste cleaning

Chen

Wang

et al. 2020

Mater. construcc.

View full text Add to dashboard Cite

This study proposes a method to convert non-structural calcium-rich construction and demolition waste fines into adsorbents of heavy metal ions by mixing waste fines with diammonium hydrogen phosphate solution to produce hydroxyapatite, which has high surface areas and excellent ion-exchange capacity with heavy metal ions. As a result, environmental polluting waste is converted into environmentally cleaning material. Waste putty powders was chosen as the representative waste to investigate the detailed formation process of hydroxyapatite and the key reaction parameters of the reaction. Results showed that hydroxyapatite can be produced on waste putty particles. Higher ageing temperatures or longer ageing duration are beneficial to the yield and crystallinity of the produced hydroxyapatite. Adsorption testing confirmed that Ni 2+ can replace Ca 2+ in the hydroxyapatite lattice, leading to the formation of a new crystal, arupite (Ni 3 (PO 4 ) 2 •8H 2 O), and contributing to a modest adsorption capacity for Ni 2+ (15 mg/g) for the hydroxyapatite-containing waste putty. Citation/Citar como: Chen, P.; Chen, X.; Wang, Y.; Wang, P. (2020) Preliminary Study on the Upcycle of Non-structural Construction and Demolition Waste for Waste Cleaning. Mater. Construcc. 70 [338], e220 https://doi.org/10.3989/ mc.2020.13819 RESUMEN:Estudio preliminar sobre el empleo de residuos de construcción y demolición no estructurales para la eliminación de residuos. Este estudio propone un método para convertir residuos de construcción y demolición no estructurales, ricos en calcio y pulverulentos, en adsorbentes de iones de metales pesados mezclándolos con una solución de hidrógenofosfato de diamonio para generar hidroxiapatita, la cual presenta una elevada área superficial y una excelente capacidad de intercambio iónico de iones de metales pesados. De este modo, un residuo contaminante se convierte en un material que limpia el medio ambiente. Se seleccionó residuo en forma de masilla en polvo como residuo representativo para investigar en detalle los procesos de formación de hidroxiapatita y los parámetros clave implicados en la reacción. Los resultados mostraron que la hidroxiapatita se puede producir en las partículas de los residuos empleados. La producción y la cristalinidad de la hidroxiapatita se ve favorecida por temperaturas de envejecimiento elevadas y prolongadas. Los ensayos de adsorción confirmaron que el Ni 2+ puede sustituir al Ca 2+ en la estructura de la hidroxiapatita, formándose un nuevo mineral, arupita (Ni 3 (PO 4 ) 2 •8H 2 O), y contribuyendo a una adsorción modesta de Ni 2+ (15 mg/g) por parte de la masilla de residuos con hidroxiapatita.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Preliminary study on the upcycle of non-structural construction and demolition waste for waste cleaning

Chen

Wang

et al. 2020

Mater. construcc.

View full text Add to dashboard Cite

show abstract

“…These characteristics make it useful for both tissue engineering (TE) and drug delivery applications [2, 7]. However due to the inherent brittle nature of hydroxyapatite nanoparticles, they are usually incorporated into polymeric nanocomposites to ensure easy processing [8, 9]. Thus, the elastic polymeric matrix overcomes the intrinsic brittleness of the bioceramic by improving upon its design flexibility.…”

Section: Introductionmentioning

confidence: 99%

Eggshell Based Nano-Engineered Hydroxyapatite and Poly(lactic) Acid Electrospun Fibers as Potential Tissue Scaffold

Apalangya

Rangari

Tiimob

et al. 2019

International Journal of Biomaterials

View full text Add to dashboard Cite

Nanocomposite electrospun fibers were fabricated from poly(lactic) acid (PLA) and needle-like hydroxyapatite nanoparticles made from eggshells. The X-ray diffraction spectrum and the scanning electron micrograph showed that the hydroxyapatite particles are highly crystalline and are needle-liked in shape with diameters between 10 and 20 nm and lengths ranging from 100 to 200 nm. The microstructural, thermal, and mechanical properties of the electrospun fibers were characterized using scanning electron microscope (SEM), thermogravimetric analysis (TGA), dynamic scanning calorimetry (DSC), and tensile testing techniques. The SEM study showed that both pristine and PLA/EnHA fibers surfaces exhibited numerous pores and rough edges suitable for cell attachment. The presence of the rod-liked EnHA particles was found to increase thermal and mechanical properties of PLA fibers relative to pristine PLA fibers. The confocal optical images showed that osteoblast cells were found to attach on dense pristine PLA and PLA/HA-10 wt% fibers after 48 hours of incubation. The stained confocal optical images indicated the secretion of cytoplasmic extension linking adjoining nuclei after 96 hours of incubation. These findings showed that eggshell based nanohydroxyapatite and poly(lactic acid) fibers could be potential scaffold for tissue regeneration.

show abstract

“…All of the BNS samples show porous and rough surface morphology. The irregular, non-smooth, and rough surface morphology help cell adhesion, while the porosity with appropriate pore size encourages cell proliferation and adhesion [49,50]. Additionally, the SEM profile has presented a different pore size to promote cell adhesion, proliferation, diffraction, and extracellular matrix secretion.…”

Section: Sem-edxmentioning

confidence: 99%

Synthesis of Silver-Coated Bioactive Nanocomposite Scaffolds Based on Grafted Beta-Glucan/Hydroxyapatite via Freeze-Drying Method: Anti-Microbial and Biocompatibility Evaluation for Bone Tissue Engineering

et al. 2020

View full text Add to dashboard Cite

Advancement and development in bone tissue engineering, particularly that of composite scaffolds, are of great importance for bone tissue engineering. We have synthesized polymeric matrix using biopolymer (β-glucan), acrylic acid, and nano-hydroxyapatite through free radical polymerization method. Bioactive nanocomposite scaffolds (BNSs) were fabricated using the freeze-drying method and Ag was coated by the dip-coating method. The scaffolds have been characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and X-ray diffraction analysis (XRD) to investigate their functional groups, surface morphology, and phase analysis, respectively. The pore size and porosity of all BNS samples were found to be dependent on silver concentration. Mechanical testing of all BNS samples have substantial compressive strength in dry form that is closer to cancellous bone. The samples of BNS showed substantial antibacterial effect against DH5 alpha E. coli. The biological studies conducted using the MC3T3-E1 cell line via neutral red dye assay on the scaffolds have found to be biocompatible and non-cytotoxic. These bioactive scaffolds can bring numerous applications for bone tissue repairs and regenerations.

show abstract

In situ synthesis and characterization of hydroxyapatite/natural rubber composites for biomedical applications

Cited by 40 publications

References 47 publications

Preliminary study on the upcycle of non-structural construction and demolition waste for waste cleaning

Preliminary study on the upcycle of non-structural construction and demolition waste for waste cleaning

Eggshell Based Nano-Engineered Hydroxyapatite and Poly(lactic) Acid Electrospun Fibers as Potential Tissue Scaffold

Synthesis of Silver-Coated Bioactive Nanocomposite Scaffolds Based on Grafted Beta-Glucan/Hydroxyapatite via Freeze-Drying Method: Anti-Microbial and Biocompatibility Evaluation for Bone Tissue Engineering

Contact Info

Product

Resources

About