“…For example, for the relatively large hydrophilic protein immunoglobulin G (IgG) (M W 10 5 ), the frequency is enhanced by a factor of ca. 1.8 (13,62), whereas for small (M W õ 5000) hydrophobic proteins no frequency enhancement is found (62,63). Since the QCM responds not only to protein mass uptake, but also to other interfacial mass change when in contact with solution, Eq.…”